Related papers: Random traction yielding transition in epithelial …
Concentrated colloidal suspensions and emulsions are amorphous soft solids, widespread in technological and industrial applications and studied as model systems in physics and material sciences. They are easily fluidized by applying a…
Animal morphogenesis involves complex tissue deformation processes, which require tight control over tissue rheology. Yet, it remains insufficiently understood how tissue rheology results from the interplay between cellular packing and…
We study the yielding transition of a two dimensional amorphous system under shear by using a mesoscopic elasto-plastic model. The model combines a full (tensorial) description of the elastic interactions in the system, and the possibility…
Mechanical characteristics of single biological cells are used to identify and possibly leverage interesting differences among cells or cell populations. Fluidity---hysteresivity normalized to the extremes of an elastic solid or a viscous…
Amorphous materials exhibit complex material proprteties with strongly nonlinear behaviors. Below a yield stress they behave as plastic solids, while they start to yield above a critical stress $\Sigma_c$. A key quantity controlling…
Yielding transitions in athermal amorphous materials resemble critical phenomena. Historically, they have been described by the Herschel-Bulkley rheological formula, which implies singular behaviors at yield points. In this paper, I examine…
Epithelization, the process whereby an epithelium covers a cell-free surface, is not only central to wound healing but also pivotal in embryonic morphogenesis, regeneration, and cancer. In the context of wound healing, the epithelization…
Cell movement, for example during embryogenesis or tumor metastasis, is a complex dynamical process resulting from an intricate interplay of multiple components of the cellular migration machinery. At first sight, the paths of migrating…
Lipid bilayer membranes are the fundamental biological barriers that permit life. The bilayer dynamics largely participates in orchestrating cellular workings and is characterized by substantial stability together with extreme plasticity…
We observe a new type of behavior in a shear thinning yield stress fluid: freestanding convection rolls driven by vertical oscillation. The convection occurs without the constraint of container boundaries yet the diameter of the rolls is…
Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…
The development of traction-force microscopy, in the past two decades, has created the unprecedented opportunity of performing direct mechanical measurements on living cells as they adhere or crawl on uniform or micro-patterned substrates.…
We analyze numerically the critical properties of a two-dimensional discretized random surface with extrinsic curvature embedded in a three-dimensional space. The use of the toroidal topology enables us to enforce the non-zero external…
Cell monolayers are a central model system to tissue biophysics. In vivo, epithelial tissues are curved on the scale of microns, and curvature's role in the onset of spontaneous tissue flows is still not well-understood. Here, we present a…
We analyse a multi-phase field model for an epithelial monolayer with pairwise adhesions between neighbouring cells following an Ornstein-Uhlenbeck process, representing the stochastic turnover of junctional molecular motors. These…
Yielding is central to the relaxation, flow and fracture of a wide range of soft and molecular glasses, but its microscopic origin remains unclear. Here, we elucidate the yielding of a colloidal glass by using x-ray scattering to monitor…
We use atomistic computer simulations to provide a microscopic description of the brittle failure of amorphous materials, and we assess the role of rare events and quenched disorder. We argue that brittle yielding originates at rare soft…
An important aspect of the physics of amorphous solids is the onset of irreversible behavior usually associated with yield. Here we study amorphous solids under periodic shear using quasi-static molecular dynamics simulations and observe a…
Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…
Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…