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Cardiovascular disease (CVD) accounts for about half of non-communicable diseases. Vessel stenosis in the coronary artery is considered to be the major risk of CVD. Computed tomography angiography (CTA) is one of the widely used noninvasive…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 An Zeng , Chunbiao Wu , Meiping Huang , Jian Zhuang , Shanshan Bi , Dan Pan , Najeeb Ullah , Kaleem Nawaz Khan , Tianchen Wang , Yiyu Shi , Xiaomeng Li , Guisen Lin , Xiaowei Xu

Segmentation of the coronary artery is an important task for the quantitative analysis of coronary computed tomography angiography (CCTA) images and is being stimulated by the field of deep learning. However, the complex structures with…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Xiaoyu Yang , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

Coronary computed tomography angiography (CCTA) provides 3D information on obstructive coronary artery disease, but cannot fully visualize high-resolution features within the vessel wall. Intravascular imaging, in contrast, can spatially…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Karim Kadry , Abhishek Karmakar , Andreas Schuh , Kersten Peterson , Michiel Schaap , David Marlevi , Charles Taylor , Elazer Edelman , Farhad Nezami

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Background: Computed Tomography Angiography (CTA) is crucial for cerebrovascular disease diagnosis. Dynamic CTA is a type of imaging that captures temporal information about the We aim to develop and evaluate two segmentation techniques to…

Medical Physics · Physics 2025-02-17 Shrikanth Yadav , Jisoo Kim , Geoffrey Young , Lei Qin

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Coronary CT angiography (CCTA) scans are widely used for diagnosis of coronary artery diseases. An accurate and automatic vessel labeling algorithm for CCTA analysis can significantly improve the diagnostic efficiency and reduce the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-05 Xu Wang , Jun Ma , Jing Li

The purpose of this study is to present a new semi-automated methodology for three-dimensional (3D) reconstruction of coronary arteries and their plaque morphology using Computed Tomography Angiography (CTA) images. The methodology is…

Targeted diagnosis and treatment plans for patients with coronary artery disease vary according to atherosclerotic plaque component. Coronary CT angiography (CCTA) is widely used for artery imaging and determining the stenosis degree.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Jun Li , Kexin Li , Yafeng Zhou , S. Kevin Zhou

Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Yo-Chuan Chen , Yi-Chen Lin , Ching-Ping Wang , Chia-Yen Lee , Wen-Jeng Lee , Tzung-Dau Wang , Chung-Ming Chen

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

Coronary artery centerline extraction in cardiac CT angiography (CCTA) images is a prerequisite for evaluation of stenoses and atherosclerotic plaque. We propose an algorithm that extracts coronary artery centerlines in CCTA using a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Jelmer M. Wolterink , Robbert W. van Hamersvelt , Max A. Viergever , Tim Leiner , Ivana Išgum

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

At present, coronary angiography is the well known standard for the diagnosis of coronary artery disease. Conventional coronary angiography is an invasive procedure with a small, yet inherent risk of myocardial infarction, stroke, potential…

Computer Vision and Pattern Recognition · Computer Science 2011-04-19 B. G. Kodge , P. S. Hiremath

Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Huan Huang , Michele Esposito , Chen Zhao

In patients with obstructive coronary artery disease, the functional significance of a coronary artery stenosis needs to be determined to guide treatment. This is typically established through fractional flow reserve (FFR) measurement,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Majd Zreik , Robbert W. van Hamersvelt , Nadieh Khalili , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Mariusz Bujny , Katarzyna Jesionek , Jakub Nalepa , Karol Miszalski-Jamka , Katarzyna Widawka-Żak , Sabina Wolny , Marcin Kostur
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