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Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

Biological function emerges from coupled constraints across sequence, structure, regulation, evolution, and cellular context, yet most foundation models in biology are trained within one modality or for a fixed forward task. We present…

The modelling of memristive devices is an essential part of the development of novel in-memory computing systems. Models are needed to enable the accurate and efficient simulation of memristor device characteristics, for purposes of testing…

Emerging Technologies · Computer Science 2024-08-06 Waleed El-Geresy , Christos Papavassiliou , Deniz Gündüz

Surface electromyography (sEMG) is a non-invasive method of measuring neuromuscular potentials generated when the brain instructs the body to perform both fine and coarse locomotion. This technique has seen extensive investigation over the…

Human-Computer Interaction · Computer Science 2021-04-06 Mingde Zheng , Michael S. Crouch , Michael S. Eggleston

In recent years, increasingly complex computational models are being built to describe physical systems which has led to increased use of surrogate models to reduce computational cost. In problems related to Structural Health Monitoring…

Machine Learning · Computer Science 2024-07-08 Nicholas E. Silionis , Theodora Liangou , Konstantinos N. Anyfantis

Despite significant recent progress in the area of Brain-Computer Interface (BCI), there are numerous shortcomings associated with collecting Electroencephalography (EEG) signals in real-world environments. These include, but are not…

Quantitative Methods · Quantitative Biology 2019-10-14 Nik Khadijah Nik Aznan , Amir Atapour-Abarghouei , Stephen Bonner , Jason Connolly , Noura Al Moubayed , Toby Breckon

Energy-Based Models (EBMs) present a flexible and appealing way to represent uncertainty. Despite recent advances, training EBMs on high-dimensional data remains a challenging problem as the state-of-the-art approaches are costly, unstable,…

Machine Learning · Computer Science 2021-06-08 Will Grathwohl , Jacob Kelly , Milad Hashemi , Mohammad Norouzi , Kevin Swersky , David Duvenaud

Deep learning models have shown high accuracy in classifying electrocardiograms (ECGs), but their black box nature hinders clinical adoption due to a lack of trust and interpretability. To address this, we propose a novel three-stage…

Machine Learning · Computer Science 2025-12-09 Jose Geraldo Fernandes , Luiz Facury de Souza , Pedro Robles Dutenhefner , Gisele L. Pappa , Wagner Meira

Generative Adversarial Nets [8] were recently introduced as a novel way to train generative models. In this work we introduce the conditional version of generative adversarial nets, which can be constructed by simply feeding the data, y, we…

Machine Learning · Computer Science 2014-11-10 Mehdi Mirza , Simon Osindero

The development of machine learning for cardiac care is severely hampered by privacy restrictions on sharing real patient electrocardiogram (ECG) data. Although generative AI offers a promising solution, the real-world use of existing…

Here we demonstrate that the activity of neural ensembles can be quantitatively modeled. We first show that an ensemble dynamical model (EDM) accurately approximates the distribution of voltages and average firing rate per neuron of a…

Neurons and Cognition · Quantitative Biology 2015-09-07 Joaquin Rapela , Mark Kostuk , Peter F. Rowat , Tim Mullen , Edward F. Chang , Kristofer Bouchard

Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

Neuromorphic circuits mimic partial functionalities of brain in a bio-inspired information processing sense in order to achieve similar efficiencies as biological systems. While there are common mathematical models for neurons, which can be…

Emerging Technologies · Computer Science 2017-09-26 Enver Solan , Karlheinz Ochs

Exponential random graph models (ERGMs) are very flexible for modeling network formation but pose difficult estimation challenges due to their intractable normalizing constant. Existing methods, such as MCMC-MLE, rely on sequential…

Social and Information Networks · Computer Science 2025-02-05 Angelo Mele

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

Recent literature suggests that the surface electromyography (sEMG) signals have non-stationary statistical characteristics specifically due to random nature of the covariance. Thus suitability of a statistical model for sEMG signals is…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Durgesh Kusuru , Anish C. Turlapaty , Mainak Thakur

We present Model-Predictive Interaction Primitives -- a robot learning framework for assistive motion in human-machine collaboration tasks which explicitly accounts for biomechanical impact on the human musculoskeletal system. First, we…

Robotics · Computer Science 2020-11-16 Geoffrey Clark , Joseph Campbell , Heni Ben Amor

Multimodal physiological signals, such as EEG, ECG, EOG, and EMG, are crucial for healthcare and brain-computer interfaces. While existing methods rely on specialized architectures and dataset-specific fusion strategies, they struggle to…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Wei-Bang Jiang , Xi Fu , Yi Ding , Cuntai Guan

Electromagnetic (EM) body models predict the impact of human presence and motions on the Radio-Frequency (RF) stray radiation received by wireless devices nearby. These wireless devices may be co-located members of a Wireless Local Area…

Signal Processing · Electrical Eng. & Systems 2023-10-09 Stefano Savazzi , Federica Fieramosca , Sanaz Kianoush , Vittorio Rampa , Michele D'amico

Quantum generative learning is a promising application of quantum computers, but faces several trainability challenges, including the difficulty in experimental gradient estimations. For certain structured quantum generative models,…

Quantum Physics · Physics 2025-11-19 Bence Bakó , Zoltán Kolarovszki , Zoltán Zimborás