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Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

Computation and Language · Computer Science 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah

Electronic Medical Records (EHR) are extremely sparse. Only a small proportion of events (symptoms, diagnoses, and treatments) are observed in the lifetime of an individual. The high degree of missingness of EHR can be attributed to a large…

Artificial Intelligence · Computer Science 2021-11-18 Ramon Vinas , Xu Zheng , Jer Hayes

Timely sharing of electronic health records (EHR) across providers is essential and significance in facilitating medical researches and prompt patients' care. With sharing, it is crucial that patients can control who can access their data…

Cryptography and Security · Computer Science 2022-03-25 Kheng-Leong Tan , Chi-Hung Chi , Kwok-Yan Lam

Electronic Health Records are electronic data generated during or as a byproduct of routine patient care. Structured, semi-structured and unstructured EHR offer researchers unprecedented phenotypic breadth and depth and have the potential…

Artificial Intelligence · Computer Science 2017-07-26 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

Software Engineering · Computer Science 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung

Missing data arise in most applied settings and are ubiquitous in electronic health records (EHR). When data are missing not at random (MNAR) with respect to measured covariates, sensitivity analyses are often considered. These post-hoc…

Methodology · Statistics 2023-07-11 Alexander W. Levis , Rajarshi Mukherjee , Rui Wang , Heidi Fischer , Sebastien Haneuse

World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved…

Artificial Intelligence · Computer Science 2026-02-04 Linjie Mu , Zhongzhen Huang , Yannian Gu , Shengqian Qin , Shaoting Zhang , Xiaofan Zhang

Objectives: In the United States, 25% of people with type 2 diabetes are undiagnosed. Conventional screening models use limited demographic information to assess risk. We evaluated whether electronic health record (EHR) phenotyping could…

Quantitative Methods · Quantitative Biology 2015-01-13 Ariana E. Anderson , Wesley T. Kerr , April Thames , Tong Li , Jiayang Xiao , Mark S. Cohen

We develop and evaluate a data-driven approach for detecting unusual (anomalous) patient-management actions using past patient cases stored in an electronic health record (EHR) system. Our hypothesis is that patient-management actions that…

Machine Learning · Computer Science 2026-05-07 Milos Hauskrecht , Michal Valko , Shyam Visweswaran , Iyad Batal , Gilles Clermont , Gregory Cooper

Electronic Health Records (EHRs) are relational databases that store the entire medical histories of patients within hospitals. They record numerous aspects of patients' medical care, from hospital admission and diagnosis to treatment and…

Computation and Language · Computer Science 2024-05-24 Gyubok Lee , Sunjun Kweon , Seongsu Bae , Edward Choi

Electronic Health Records (EHR) contain rich longitudinal patient information and are widely used in predictive modeling applications. However, effectively leveraging historical data remains challenging due to long trajectories,…

Information Retrieval · Computer Science 2026-05-13 Saeed Shurrab , Mariam Al-Omari , Dana El Samad , Farah E. Shamout

The translation of clinical decision support system (CDSS) tools from research settings into the clinic is often non-existent, partly because the focus tends to be on training machine learning models rather than tool development using the…

The fairness issue of clinical data modeling, especially on Electronic Health Records (EHRs), is of utmost importance due to EHR's complex latent structure and potential selection bias. It is frequently necessary to mitigate health…

Machine Learning · Computer Science 2023-10-03 Zheng Liu , Xiaohan Li , Philip Yu

In this work we addressed the problem of capturing sequential information contained in longitudinal electronic health records (EHRs). Clinical notes, which is a particular type of EHR data, are a rich source of information and practitioners…

Computation and Language · Computer Science 2020-10-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Hao Ni , Goran Nenadic , Alejo Nevado-Holgado

Effective summarization of unstructured patient data in electronic health records (EHRs) is crucial for accurate diagnosis and efficient patient care, yet clinicians often struggle with information overload and time constraints. This review…

Computers and Society · Computer Science 2024-07-25 Chanseo Lee , Kimon-Aristotelis Vogt , Sonu Kumar

Electronic Health Records (EHRs), comprising diverse clinical data such as diagnoses, medications, and laboratory results, hold great promise for translational research. EHR-derived data have advanced disease prevention, improved clinical…

Machine Learning · Statistics 2025-09-09 Yinjie Wang , Doudou Zhou , Yue Liu , Junwei Lu , Tianxi Cai

Social determinants of health (SDoH) have an important impact on patient outcomes but are incompletely collected from the electronic health records (EHR). This study researched the ability of large language models to extract SDoH from free…

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

Electronic health record (EHR) data are increasingly used to support real-world evidence (RWE) studies. Yet its ability to generate reliable RWE is limited by the lack of readily available precise information on the timing of clinical…

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