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Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

A Digital Twin (DT) is a virtual replica of a physical object or system, created to monitor, analyze, and optimize its behavior and characteristics. A Spatial Digital Twin (SDT) is a specific type of digital twin that emphasizes the…

Computers and Society · Computer Science 2023-06-13 Mohammed Eunus Ali , Muhammad Aamir Cheema , Tanzima Hashem , Anwaar Ulhaq , Muhammad Ali Babar

The dramatic increase in the connectivity demand results in an excessive amount of Internet of Things (IoT) sensors. To meet the management needs of these large-scale networks, such as accurate monitoring and learning capabilities, Digital…

Networking and Internet Architecture · Computer Science 2023-11-27 Kubra Duran , Matthew Broadbent , Gokhan Yurdakul , Berk Canberk

Digital Twin (DT) technologies are transforming manufacturing by enabling real-time prediction, monitoring, and control of complex processes. Yet, applying DT to deformation-based metal forming remains challenging because of the strongly…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Yi-Ping Chen , Derick Suarez , Ying-Kuan Tsai , Vispi Karkaria , Guanzhong Hu , Zihan Chen , Ping Guo , Jian Cao , Wei Chen

Human Digital Twins (HDTs) are a fast-emerging technology with significant potential in fields ranging from healthcare to sports. HDTs extend the traditional understanding of Digital Twins by representing humans as the underlying physical…

Human-Computer Interaction · Computer Science 2024-02-14 Martin Wolfgang Lauer-Schmaltz , Philip Cash , John Paulin Hansen , Anja Maier

Digital twin (DT) technology enables real-time simulation, prediction, and optimization of physical systems, but practical deployment faces challenges from high data requirements, proprietary data constraints, and limited adaptability to…

Conjoint analysis is a cornerstone of market research for estimating consumer preferences; however, traditional methods face persistent challenges regarding time, cost, and respondent fatigue. To address these limitations, this study…

Information Retrieval · Computer Science 2026-04-28 Bin Xuan , Jungmin Hwang , Hakyeon Lee

In this paper, we propose a novel efficient digital twin (DT) data processing scheme to reduce service latency for multicast short video streaming. Particularly, DT is constructed to emulate and analyze user status for multicast group…

Networking and Internet Architecture · Computer Science 2024-04-23 Xinyu Huang , Shisheng Hu , Mushu Li , Cheng Huang , Xuemin Shen

This paper investigates the integration of large language models (LLMs) as reasoning agents in repeated spectrum auctions within heterogeneous networks (HetNets). While auction-based mechanisms have been widely employed for efficient…

Networking and Internet Architecture · Computer Science 2026-03-06 Ismail Lotfi , Ali Ghrayeb , Samson Lasaulce , Merouane Debbah

This paper proposes a diffusion-based auto-bidding framework that leverages graph representations to model large-scale auction environments. In such settings, agents must dynamically optimize bidding strategies under constraints defined by…

Machine Learning · Computer Science 2025-04-22 Dom Huh , Prasant Mohapatra

Complex IoT ecosystems often require the usage of Digital Twins (DTs) of their physical assets in order to perform predictive analytics and simulate what-if scenarios. DTs are able to replicate IoT devices and adapt over time to their…

Networking and Internet Architecture · Computer Science 2024-01-02 Luca Sciullo , Alberto De Marchi , Angelo Trotta , Federico Montori , Luciano Bononi , Marco Di Felice

Multi-robot system for manufacturing is an Industry Internet of Things (IIoT) paradigm with significant operational cost savings and productivity improvement, where Unmanned Aerial Vehicles (UAVs) are employed to control and implement…

Information Theory · Computer Science 2023-05-04 Kai Xiong , Zhihong Wang , Supeng Leng , Jianhua He

We propose and demonstrate a holographic imaging scheme exploiting random illuminations for recording hologram and then applying numerical reconstruction and twin removal. We use an in-line holographic geometry to record the hologram in…

Crowdsourced mobile video streaming enables nearby mobile video users to aggregate network resources to improve their video streaming performances. However, users are often selfish and may not be willing to cooperate without proper…

Networking and Internet Architecture · Computer Science 2018-07-10 Ming Tang , Haitian Pang , Shou Wang , Lin Gao , Jianwei Huang , Lifeng Sun

Federated Learning (FL) is a distributed learning framework that can deal with the distributed issue in machine learning and still guarantee high learning performance. However, it is impractical that all users will sacrifice their resources…

Machine Learning · Computer Science 2020-09-23 Tra Huong Thi Le , Nguyen H. Tran , Yan Kyaw Tun , Minh N. H. Nguyen , Shashi Raj Pandey , Zhu Han , Choong Seon Hong

Federated learning makes it possible for all parties with data isolation to train the model collaboratively and efficiently while satisfying privacy protection. To obtain a high-quality model, an incentive mechanism is necessary to motivate…

Computer Science and Game Theory · Computer Science 2022-05-18 Jingwen Zhang , Yuezhou Wu , Rong Pan

Optimizing modern wireless networks is exceptionally challenging due to their high dynamism and complexity. While the agentic artificial intelligence (AI) powered by reinforcement learning (RL) offers a promising solution, its practical…

Systems and Control · Electrical Eng. & Systems 2025-11-26 Zhenyu Tao , Wei Xu , Xiaohu You

Digital twins are models of real-world systems that can simulate their dynamics in response to potential actions. In complex settings, the state and action variables, and available data and knowledge relevant to a system can constantly…

Computation and Language · Computer Science 2025-07-23 Harry Amad , Nicolás Astorga , Mihaela van der Schaar

Digital twins have been introduced as supporters to city operations, yet existing scene-descriptor formats and digital twin platforms often lack the integration, federation, and adaptable connectivity that urban environments demand. Modern…

Networking and Internet Architecture · Computer Science 2025-09-16 Ioannis Tsampras , Georgios Stergiopoulos , Tanya Politi , Spyros Denazis

In [1], we proposed a two-tier model for creating and maintaining a distributed hash table (DHT) overlay of smartphones. The purpose was to reduce Internet usage and increase D2D content sharing over LTE-A/5G network. However, the real…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-11 Sumit Kumar Tetarave , Somanath Tripathy , R. K. Ghosh