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Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

The aim of this paper is to give an overview of brain organoid computing, its characteristics, challenges, as well as possible advantages for future applications in the field of artificial intelligence. An important part is the extensive…

Emerging Technologies · Computer Science 2025-11-04 Yannic Talavera , Bernd Ulmann

Organoids are self-organized 3D cell clusters that closely mimic the architecture and function of in vivo tissues and organs. Quantification of organoid morphology helps in studying organ development, drug discovery, and toxicity…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Xiaodan Xing , Chunling Tang , Yunzhe Guo , Nicholas Kurniawan , Guang Yang

Stem cell-derived organoids are a promising tool to model native human tissues as they resemble human organs functionally and structurally compared to traditional monolayer cell-based assays. For instance, colon organoids can spontaneously…

Quantitative Methods · Quantitative Biology 2022-10-14 Lyan Abdul , Jocelyn Xu , Alexander Sotra , Abbas Chaudary , Jerry Gao , Shravanthi Rajasekar , Nicky Anvari , Hamidreza Mahyar , Boyang Zhang

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega

Introduction: The present study on the development and evaluation of an automated brain tumor segmentation technique based on deep learning using the 3D U-Net model. Objectives: The objective is to leverage state-of-the-art convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Suman Sourabh , Murugappan Valliappan , Narayana Darapaneni , Anwesh R P

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Brain tumor segmentation is highly contributive in diagnosing and treatment planning. The manual brain tumor delineation is a time-consuming and tedious task and varies depending on the radiologists skill. Automated brain tumor segmentation…

Medical Physics · Physics 2022-03-08 Farzaneh Dehghani , Alireza Karimian , Hossein Arabi

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

It is still not fully understood exactly how neural networks are able to solve the complex tasks that have recently pushed AI research forward. We present a novel method for determining how information is structured inside a neural network.…

Neural and Evolutionary Computing · Computer Science 2019-02-04 Peter E. Lillian , Richard Meyes , Tobias Meisen

Medical image segmentation has become an essential technique in clinical and research-oriented applications. Because manual segmentation methods are tedious, and fully automatic segmentation lacks the flexibility of human intervention or…

Image and Video Processing · Electrical Eng. & Systems 2019-04-24 Kevin Karsch , Qing He , Ye Duan

The analysis of animal cross section images, such as cross sections of laboratory mice, is critical in assessing the effect of experimental drugs such as the biodistribution of candidate compounds in preclinical drug development stage.…

Computer Vision and Pattern Recognition · Computer Science 2018-07-18 Naveen Ashish , Mi-Youn Brusniak

Brain signals constitute the information that are processed by millions of brain neurons (nerve cells and brain cells). These brain signals can be recorded and analyzed using various of non-invasive techniques such as the…

Neurons and Cognition · Quantitative Biology 2022-01-13 Almabrok Essa , Hari Kotte

Radiation therapy has emerged as one of the preferred techniques to treat brain cancer patients. During treatment, a very high dose of radiation is delivered to a very narrow area. Prescribed radiation therapy for brain cancer requires…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Jose Dolz , Nicolas Reyns , Nacim Betrouni , Dris Kharroubi , Mathilde Quidet , Laurent Massoptier , Maximilien Vermandel

Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level…

Machine Learning · Computer Science 2024-05-02 Kaiqiao Han , Yi Yang , Zijie Huang , Xuan Kan , Yang Yang , Ying Guo , Lifang He , Liang Zhan , Yizhou Sun , Wei Wang , Carl Yang
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