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The evolution of microbial and viral organisms often generates clonal interference, a mode of competition between genetic clades within a population. In this paper, we show that interference strongly constrains the genetic and phenotypic…

Populations and Evolution · Quantitative Biology 2019-06-12 Torsten Held , Daniel Klemmer , Michael Lässig

The learning dynamics of biological brains and artificial neural networks are of interest to both neuroscience and machine learning. A key difference between them is that neural networks are often trained from a randomly initialized state…

Neural and Evolutionary Computing · Computer Science 2025-05-19 Benjamin Midler , Alejandro Pan Vazquez

Plasmids are major players in Horizontal Gene Transfer mechanisms, hence they are highly variable in their gene content and length. We propose a model for the fitness of a plasmid as a function of its length, which predicts diminishing…

Populations and Evolution · Quantitative Biology 2014-11-04 Alice Ledda , Luca Ferretti

Boolean networks have been widely used to explore aspects of gene regulation, traditionally with a single network. A modified form of the model to explore the effects of increasing the number of gene states has also recently been…

Molecular Networks · Quantitative Biology 2024-01-22 Larry Bull

Much recent work has explored molecular and population-genetic constraints on the rate of protein sequence evolution. The best predictor of evolutionary rate is expression level, for reasons which have remained unexplained. Here, we…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Allan Drummond , Jesse D. Bloom , Christoph Adami , Claus O. Wilke , Frances H. Arnold

We have used the Monte Carlo based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to critical crossover rate, where genomes may switch between the…

Genomics · Quantitative Biology 2015-05-13 Jakub Kowalski , Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

Mutations are typically classified by their effects on the nucleotide sequence and by their size. Here, we argue that if our main aim is to understand the effect of mutations on evolutionary outcomes (such as adaptation or speciation), we…

Other Quantitative Biology · Quantitative Biology 2020-09-30 Emma L. Berdan , Alexandre Blanckaert , Tanja Slotte , Alexander Suh , Anja M. Westram , Inês Fragata

Technological knowledge evolves not only through the generation of new ideas, but also through the reinterpretation of existing ones. Reinterpretations lead to changes in the classification of knowledge, that is, reclassification. This…

General Economics · Economics 2025-06-11 Peter Persoon

We investigate a selection-mutation model for the dynamics of technological innovation,a special case of reaction-diffusion equations. Although mutations are assumed to increase the variety of technologies, not their average success…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Martin Treiber , Nicole J. Saam

Multilevel selection occurs when short-term individual-level reproductive interests conflict with longer-term group-level fitness effects. Detecting and quantifying this phenomenon is key to understanding evolution of traits ranging from…

Populations and Evolution · Quantitative Biology 2026-01-12 Matthew Andres Moreno , Sanaz Hasanzadeh Fard , Luis Zaman , Emily Dolson

This paper develops a quasispecies model where cells can adopt a two-cell survival strategy. Within this strategy, pairs of cells join together, at which point one of the cells sacrifices its own replicative ability for the sake of the…

Populations and Evolution · Quantitative Biology 2009-11-11 Emmanuel Tannenbaum

How individuals adapt their behavior in cultural evolution remains elusive. Theoretical studies have shown that the update rules chosen to model individual decision making can dramatically modify the evolutionary outcome of the population…

Physics and Society · Physics 2018-12-26 Lei Zhou , Bin Wu , Vítor V. Vasconcelos , Long Wang

Using a bit string model, we show that asexual reproduction for diploids is more efficient than for haploids: it improves genetic material producing new individuals with less deleterious mutations. We also see that in a system where…

Statistical Mechanics · Physics 2009-11-07 Armando Ticona , Paulo Murilo C. de Oliveira

Environmental changes greatly influence the evolution of populations. Here, we study the dynamics of a population of two strains, one growing slightly faster than the other, competing for resources in a time-varying binary environment…

Populations and Evolution · Quantitative Biology 2020-07-28 Ami Taitelbaum , Robert West , Michael Assaf , Mauro Mobilia

Range expansion is a universal process in biological systems, and therefore plays a part in biological evolution. Using a quantitative individual-based method based on the stochastic process, we identify that enhancing the inherent…

Populations and Evolution · Quantitative Biology 2022-01-17 Xiaoliang Wang , Andrew Harrison

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

We present a new method for proving lower bounds on the expected running time of evolutionary algorithms. It is based on fitness-level partitions and an additional condition on transition probabilities between fitness levels. The method is…

Neural and Evolutionary Computing · Computer Science 2015-03-19 Dirk Sudholt

In this paper, we consider a new kind of evolution multivalued quasi-variational inequalities with feedback effect and a nonlinear bifunction which contain several (evolution) quasi-variational/hemivariational inequalities as special cases.…

Functional Analysis · Mathematics 2024-05-29 Shengda Zeng , Vicenţiu D. Rădulescu

The theory of evolution by natural selection cannot be used to evaluate the truth value of the following proposition: Through evolution, there exists at least one species that can adapt to any one given environment. To address this issue,…

Biological Physics · Physics 2022-08-17 Kai Xu
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