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Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable image…

Image-based precision medicine aims to personalize treatment decisions based on an individual's unique imaging features so as to improve their clinical outcome. Machine learning frameworks that integrate uncertainty estimation as part of…

Machine Learning · Computer Science 2023-08-11 Joshua Durso-Finley , Jean-Pierre Falet , Raghav Mehta , Douglas L. Arnold , Nick Pawlowski , Tal Arbel

For responsible decision making in safety-critical settings, machine learning models must effectively detect and process edge-case data. Although existing works show that predictive uncertainty is useful for these tasks, it is not evident…

Machine Learning · Computer Science 2022-08-09 Mark Penrod , Harrison Termotto , Varshini Reddy , Jiayu Yao , Finale Doshi-Velez , Weiwei Pan

Background: Pancreatic cancer is one of the most aggressive cancers, with poor survival rates. Endoscopic ultrasound (EUS) is a key diagnostic modality, but its effectiveness is constrained by operator subjectivity. This study evaluates a…

Uncertainty estimation bears the potential to make deep learning (DL) systems more reliable. Standard techniques for uncertainty estimation, however, come along with specific combinations of strengths and weaknesses, e.g., with respect to…

Machine Learning · Computer Science 2022-05-02 Joachim Sicking , Maram Akila , Jan David Schneider , Fabian Hüger , Peter Schlicht , Tim Wirtz , Stefan Wrobel

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Tight-frame, a generalization of orthogonal wavelets, has been used successfully in various problems in image processing, including inpainting, impulse noise removal, super-resolution image restoration, etc. Segmentation is the process of…

Numerical Analysis · Mathematics 2015-03-19 Xiaohao Cai , Raymond Chan , Serena Morigi , Fiorella Sgallari

We describe a method for verifying the output of a deep neural network for medical image segmentation that is robust to several classes of random as well as worst-case perturbations i.e. adversarial attacks. This method is based on a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Fahim Ahmed Zaman , Xiaodong Wu , Weiyu Xu , Milan Sonka , Raghuraman Mudumbai

Automatic segmentation of multiple organs and tumors from 3D medical images such as magnetic resonance imaging (MRI) and computed tomography (CT) scans using deep learning methods can aid in diagnosing and treating cancer. However, organs…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Hao Li , Yang Nan , Javier Del Ser , Guang Yang

On-line segmentation of the uterus can aid effective image-based guidance for precise delivery of dose to the target tissue (the uterocervix) during cervix cancer radiotherapy. 3D ultrasound (US) can be used to image the uterus, however,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Bahareh Behboodi , Hassan Rivaz , Susan Lalondrelle , Emma Harris

Medical image foundation models have shown the ability to segment organs and tumors with minimal fine-tuning. These models are typically evaluated on task-specific in-distribution (ID) datasets. However, reliable performance on ID datasets…

Image and Video Processing · Electrical Eng. & Systems 2025-01-31 Aneesh Rangnekar , Nishant Nadkarni , Jue Jiang , Harini Veeraraghavan

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Recent studies have confirmed cardiovascular diseases remain responsible for highest death toll amongst non-communicable diseases. Accurate left ventricular (LV) volume estimation is critical for valid diagnosis and management of various…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 F. Terhag , P. Knechtges , A. Basermann , R. Tempone

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus

One of the most common tasks in medical imaging is semantic segmentation. Achieving this segmentation automatically has been an active area of research, but the task has been proven very challenging due to the large variation of anatomy…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Holger R. Roth , Chen Shen , Hirohisa Oda , Masahiro Oda , Yuichiro Hayashi , Kazunari Misawa , Kensaku Mori

The ability of three-dimensional (3D) spheroid modeling to study the invasive behavior of breast cancer cells has drawn increased attention. The deep learning-based image processing framework is very effective at speeding up the cell…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Thanh-Huy Nguyen , Thi Kim Ngan Ngo , Mai Anh Vu , Ting-Yuan Tu

In safety-critical applications like medical diagnosis, certainty associated with a model's prediction is just as important as its accuracy. Consequently, uncertainty estimation and reduction play a crucial role. Uncertainty in predictions…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Abhishek Singh Sambyal , Narayanan C. Krishnan , Deepti R. Bathula

Accurate detection and segmentation of anatomical structures from ultrasound images are crucial for clinical diagnosis and biometric measurements. Although ultrasound imaging has been widely used with superiorities such as low cost and…

Computer Vision and Pattern Recognition · Computer Science 2016-07-08 Hao Chen , Yefeng Zheng , Jin-Hyeong Park , Pheng-Ann Heng , S. Kevin Zhou

For navigation of robots, image segmentation is an important component to determining a terrain's traversability. For safe and efficient navigation, it is key to assess the uncertainty of the predicted segments. Current uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Judith Dijk , Gertjan Burghouts , Kapil D. Katyal , Bryanna Y. Yeh , Craig T. Knuth , Ella Fokkinga , Tejaswi Kasarla , Pascal Mettes

Medical Imagings are considered one of the crucial diagnostic tools for different bones-related diseases, especially bones fractures. This paper investigates the robustness of pre-trained deep learning models for classifying bone fractures…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Robby Hoover , Nelly Elsayed , Zag ElSayed , Chengcheng Li