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We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta

The minimization of loss functions is the heart and soul of Machine Learning. In this paper, we propose an off-the-shelf optimization approach that can minimize virtually any non-differentiable and non-decomposable loss function (e.g.…

Machine Learning · Computer Science 2019-05-27 Josif Grabocka , Randolf Scholz , Lars Schmidt-Thieme

State-of-the-art neural networks are vulnerable to adversarial examples; they can easily misclassify inputs that are imperceptibly different than their training and test data. In this work, we establish that the use of cross-entropy loss…

Machine Learning · Computer Science 2019-01-25 Kamil Nar , Orhan Ocal , S. Shankar Sastry , Kannan Ramchandran

The accuracy of deep learning methods for two foundational tasks in medical image analysis -- detection and segmentation -- can suffer from class imbalance. We propose a `switching loss' function that adaptively shifts the emphasis between…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Deepak Anand , Gaurav Patel , Yaman Dang , Amit Sethi

In neural networks, the loss function represents the core of the learning process that leads the optimizer to an approximation of the optimal convergence error. Convolutional neural networks (CNN) use the loss function as a supervisory…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Riccardo La Grassa , Ignazio Gallo , Nicola Landro

Algorithms in machine learning and AI do critically depend on at least three key components: (i) the risk function, which is the expectation of the loss function, (ii) the function space, which is often called the hypothesis space, and…

Machine Learning · Statistics 2026-05-08 Lena Helgerth , Andreas Christmann

Binaural reproduction aims to deliver immersive spatial audio with high perceptual realism over headphones. Loss functions play a central role in optimizing and evaluating algorithms that generate binaural signals. However, traditional…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-03 Boaz Rafaely , Stefan Weinzierl , Or Berebi , Fabian Brinkmann

Deep-learning has proved in recent years to be a powerful tool for image analysis and is now widely used to segment both 2D and 3D medical images. Deep-learning segmentation frameworks rely not only on the choice of network architecture but…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Carole H Sudre , Wenqi Li , Tom Vercauteren , Sébastien Ourselin , M. Jorge Cardoso

Large Language Models (LLMs) have demonstrated impressive performance across various tasks. However, current training approaches combine standard cross-entropy loss with extensive data, human feedback, or ad hoc methods to enhance…

Computation and Language · Computer Science 2024-12-16 Daniele Rege Cambrin , Giuseppe Gallipoli , Irene Benedetto , Luca Cagliero , Paolo Garza

We derive a family of loss functions to train models in the presence of sampling bias. Examples are when the prevalence of a pathology differs from its sampling rate in the training dataset, or when a machine learning practioner rebalances…

Binary classification is a common statistical learning problem in which a model is estimated on a set of covariates for some outcome indicating the membership of one of two classes. In the literature, there exists a distinction between hard…

Machine Learning · Statistics 2014-11-20 Patrick K. Kimes , D. Neil Hayes , J. S. Marron , Yufeng Liu

Loss functions are error metrics that quantify the difference between a prediction and its corresponding ground truth. Fundamentally, they define a functional landscape for traversal by gradient descent. Although numerous loss functions…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Chaitanya Kaul , Nick Pears , Hang Dai , Roderick Murray-Smith , Suresh Manandhar

Objective functions that optimize deep neural networks play a vital role in creating an enhanced feature representation of the input data. Although cross-entropy-based loss formulations have been extensively used in a variety of supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Deen Dayal Mohan , Bhavin Jawade , Srirangaraj Setlur , Venu Govindaraj

An anomalous sound detection system to detect unknown anomalous sounds usually needs to be built using only normal sound data. Moreover, it is desirable to improve the system by effectively using a small amount of anomalous sound data,…

Sound · Computer Science 2021-06-14 Ibuki Kuroyanagi , Tomoki Hayashi , Kazuya Takeda , Tomoki Toda

Loss function learning is a new meta-learning paradigm that aims to automate the essential task of designing a loss function for a machine learning model. Existing techniques for loss function learning have shown promising results, often…

Machine Learning · Computer Science 2025-10-14 Christian Raymond , Qi Chen , Bing Xue , Mengjie Zhang

In this paper we refine the process of computing calibration functions for a number of multiclass classification surrogate losses. Calibration functions are a powerful tool for easily converting bounds for the surrogate risk (which can be…

Machine Learning · Statistics 2016-09-22 Bernardo Ávila Pires , Csaba Szepesvári

Cross-entropy loss and focal loss are the most common choices when training deep neural networks for classification problems. Generally speaking, however, a good loss function can take on much more flexible forms, and should be tailored for…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Zhaoqi Leng , Mingxing Tan , Chenxi Liu , Ekin Dogus Cubuk , Xiaojie Shi , Shuyang Cheng , Dragomir Anguelov

We consider optimization of generalized performance metrics for binary classification by means of surrogate losses. We focus on a class of metrics, which are linear-fractional functions of the false positive and false negative rates…

Machine Learning · Computer Science 2016-10-10 Wojciech Kotłowski , Krzysztof Dembczyński

Medical images commonly exhibit multiple abnormalities. Predicting them requires multi-class classifiers whose training and desired reliable performance can be affected by a combination of factors, such as, dataset size, data source,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Sameer Antani

Deep learning has become the method of choice in many application domains of machine learning in recent years, especially for multi-class classification tasks. The most common loss function used in this context is the cross-entropy loss,…

Machine Learning · Computer Science 2017-04-21 Yehezkel S. Resheff , Amit Mandelbaum , Daphna Weinshall