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In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…
This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…
Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…
Current weakly-supervised incremental learning for semantic segmentation (WILSS) approaches only consider replacing pixel-level annotations with image-level labels, while the training images are still from well-designed datasets. In this…
Generative Adversarial Networks (GANs) typically suffer from overfitting when limited training data is available. To facilitate GAN training, current methods propose to use data-specific augmentation techniques. Despite the effectiveness,…
Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…
Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…
Whole-slide images (WSI) in computational pathology have high resolution with gigapixel size, but are generally with sparse regions of interest, which leads to weak diagnostic relevance and data inefficiency for each area in the slide. Most…
Weak spectral responses in hyperspectral images are often obscured by dominant endmembers and sensor noise, resulting in inaccurate abundance estimation. This paper introduces WS-Net, a deep unmixing framework specifically designed to…
In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…
Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…
Weakly supervised object detection (WSOD) is a challenging task when provided with image category supervision but required to simultaneously learn object locations and object detectors. Many WSOD approaches adopt multiple instance learning…
The state of the art in semantic segmentation is steadily increasing in performance, resulting in more precise and reliable segmentations in many different applications. However, progress is limited by the cost of generating labels for…
Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…
Conventional image classifiers are trained by randomly sampling mini-batches of images. To achieve state-of-the-art performance, practitioners use sophisticated data augmentation schemes to expand the amount of training data available for…
Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…
Whole Slide Images (WSIs) are typically analyzed using multiple instance learning (MIL) methods. However, the scale and heterogeneity of WSIs generate highly redundant and dispersed information, making it difficult to identify and integrate…
Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…
Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…
Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…