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Related papers: Translocation through conical pores: A direction-d…

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The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration…

Soft Condensed Matter · Physics 2015-06-12 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

Polymers in a melt may be subject to topological constraints, as in the example of unlinked polymer rings. How to do statistical mechanics in the presence of such constraints remains a fundamental open problem. We study the effect of…

Statistical Mechanics · Physics 2015-12-04 Pablo Serna , Guy Bunin , Adam Nahum

The paper deals with a theoretical investigation of the peristaltic transport of a physiological fluid in a porous asymmetric channel under the action of a magnetic field. The stream function, pressure gradient and axial velocity are…

Fluid Dynamics · Physics 2010-06-04 J. C. Misra , S. Maiti , G. C. Shit

The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…

Fluid Dynamics · Physics 2013-06-21 Hongzhi Lan , Soojung Claire Hur , Dino Di Carlo , Damir B. Khismatullin

The threading of a polymer chain through a small pore is a classic problem in polymer dynamics and underlies nanopore sensing technology. However important experimental aspects of the polymer motion in a solid-state nanopore, such as an…

Biological Physics · Physics 2016-07-18 Nicholas A. W. Bell , Ulrich F. Keyser

Simulating percolation and critical phenomena of labelled species inside films composed of single-component linear homogeneous macromolecules using molecular Monte Carlo method in 3 dimensions, we study dependence of these conducting…

Soft Condensed Matter · Physics 2019-09-05 Yuki Norizoe , Hiroshi Morita

We study the crossing time statistic of diffusing point particles between the two ends of expanding and narrowing two-dimensional conical channels under a transverse external gravitational field. The theoretical expression for the mean…

Statistical Mechanics · Physics 2023-01-11 Ivan Pompa-Garcia , Rodrigo Castilla , Ralf Metzler , Leonardo Dagdug

We consider an anisotropically two-dimensional diffusion of a charged molecule (particle) through a large biological channel under an external voltage. The channel is modeled as a cylinder of three structure parameters: radius, length, and…

Soft Condensed Matter · Physics 2016-02-01 V. T. N. Huyen , Le Bin Ho , Vu Cong Lap , V. Lien Nguyen

Polymers confined in corrugated channels, i.e. channels of varying amplitude, display {multiple local maxima and minima of the diffusion coefficient upon increasing their degree of polymerization $N$}. We propose a theoretical effective…

Soft Condensed Matter · Physics 2023-08-28 Emanuele Locatelli , Valentino Bianco , Chantal Valeriani , Paolo Malgaretti

Dimerization and subsequent aggregation of polymers and biopolymers often occur under nonequilibrium conditions. When the initial state of the polymer is not collapsed or the final folded native state, the dynamics of dimerization can…

Soft Condensed Matter · Physics 2024-11-19 Sangita Mondal , Ved Mahajan , Biman Bagchi

Active polymer translocation through confined spaces is a key biological process underlying DNA transport through nuclear pores and actin filament dynamics in cell migration. Here, we use living polymer-like Tubifex tubifex worms as a model…

Soft Condensed Matter · Physics 2025-04-28 Marin Vatin , Rosa Sinaasappel , Renske Kamping , Chantal Valeriani , Emanuele Locatelli , Antoine Deblais

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

A multiscale approach is used to simulate the translocation of DNA through a nanopore. Within this scheme, the interactions of the molecule with the surrounding fluid (solvent) are explicitly taken into account. By generating polymers of…

Biological Physics · Physics 2009-11-13 Simone Melchionna , Maria Fyta , Efthimios Kaxiras , Sauro Succi

We analyze the diffusive transport of Brownian particles in narrow channels with periodically varying cross-section. The geometrical confinements lead to entropic barriers, the particle has to overcome in order to proceed in transport…

Statistical Mechanics · Physics 2012-01-06 P. S. Burada , G. Schmid , Y. Li , P. Hanggi

Polymer transport is investigated for two paradigmatic laminar flows having open and closed streamlines, respectively. For both types of flows we find transport depletion owing to the action of the polymers elastic degree of freedom. For…

Chaotic Dynamics · Physics 2007-05-23 M. De Lucia , A. Mazzino , A. Vulpiani

Living organisms employ diverse strategies to navigate confined environments. Inspired by translocation observations on California blackworms (\textit{Lumbriculus variegatus}), we combine biological experiments and active-polymer…

Soft Condensed Matter · Physics 2025-10-21 K. R. Prathyusha , Paulami Sarkar , Justin Xu , Saad Bhamla

The ability of eukaryotic cells to squeeze through constrictions is limited by the stiffness of their large and rigid nucleus. However, migrating cells are often able to overcome this limitation and pass through constrictions much smaller…

Biological Physics · Physics 2023-12-20 Sirine Amiri , Yirui Zhang , Andonis Gerardos , Cécile Sykes , Pierre Ronceray

We report a numerical study of the diffusiophoresis of short polymers using non-equilibrium molecular dynamics simulations. More precisely, we consider polymer chains in a fluid containing a solute which has a concentration gradient, and…

Soft Condensed Matter · Physics 2020-05-20 Simón Ramírez-Hinestrosa , Hiroaki Yoshida , Lydéric Bocquet , Daan Frenkel

We combine quantum-chemical calculations and molecular dynamics simulations to consider aqueous ion flow across non-axisymmetric nanopores in monolayer graphene and MoS$_2$. When the pore-containing membrane is subject to uniaxial tensile…

Applied Physics · Physics 2020-04-30 A. Smolyanitsky , A. Fang , A. F. Kazakov , E. Paulechka

This paper reports the force spectroscopy analysis of a polymer that translocates from one side of a membrane to the other side through an extended pore, pulled by a cantilever that moves with constant velocity against the damping and the…

Soft Condensed Matter · Physics 2018-12-12 Alessandro Fiasconaro , Fernando Falo