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In molecular research, the modelling and analysis of molecules through simulation is an important part that has a direct influence on medical development, material science and drug discovery. The processing power required to design protein…

Quantum Physics · Physics 2026-03-24 Prateek Jain , Param Pathak , Krishna Bhatia , Shalini Devendrababu , Srinjoy Ganguly

Existing drug discovery pipelines take 5-10 years and cost billions of dollars. Computational approaches aim to sample from regions of the whole molecular and solid-state compounds called chemical space which could be on the order of 1060 .…

Emerging Technologies · Computer Science 2021-01-12 Junde Li , Rasit Topaloglu , Swaroop Ghosh

The drug design process currently requires considerable time and resources to develop each new compound that enters the market. This work develops an application of hybrid quantum generative models based on the integration of parametrized…

Traditional drug discovery pipeline takes several years and cost billions of dollars. Deep generative and predictive models are widely adopted to assist in drug development. Classical machines cannot efficiently produce atypical patterns of…

Emerging Technologies · Computer Science 2021-04-05 Junde Li , Mahabubul Alam , Congzhou M Sha , Jian Wang , Nikolay V. Dokholyan , Swaroop Ghosh

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Quantum machine learning has recently attracted much attention from the community of quantum computing. In this paper, we explore the ability of generative adversarial networks (GANs) based on quantum computing. More specifically, we…

Quantum Physics · Physics 2020-06-23 Haozhen Situ , Zhimin He , Yuyi Wang , Lvzhou Li , Shenggen Zheng

Navigating the vast chemical space of molecular structures to design novel drug molecules with desired target properties remains a central challenge in drug discovery. Recent advances in generative models offer promising solutions. This…

Generative Adversarial Networks (GANs) have demonstrated immense potential in synthesizing diverse and high-fidelity images. However, critical questions remain unanswered regarding how quantum principles might best enhance their…

In this article, we present a hybrid quantum-classical generative adversarial network (GAN) for near-term quantum processors. The hybrid GAN comprises a generator and a discriminator quantum neural network (QNN). The generator network is…

Quantum Physics · Physics 2023-07-19 Albha O'Dwyer Boyle , Reza Nikandish

The development of new drugs is a tedious, time-consuming, and expensive process, for which the average costs are estimated to be up to around $2.5 billion. The first step in this long process is the design of the new drug, for which de…

Quantum Physics · Physics 2026-03-25 Julien Baglio , Yacine Haddad , Richard Polifka

Generative adversarial networks (GANs) have emerged as a powerful paradigm for producing high-fidelity data samples, yet their performance is constrained by the quality of latent representations, typically sampled from classical noise…

Quantum Physics · Physics 2025-08-19 Kun Ming Goh

In this pioneering research paper, we present a groundbreaking exploration into the synergistic fusion of classical and quantum computing paradigms within the realm of Generative Adversarial Networks (GANs). Our objective is to seamlessly…

Quantum Physics · Physics 2023-12-29 Sahil Nokhwal , Suman Nokhwal , Saurabh Pahune , Ankit Chaudhary

Quantum Generative Adversarial Networks (QGANs) have emerged as a promising direction in quantum machine learning, combining the strengths of quantum computing and adversarial training to enable efficient and expressive generative modeling.…

Quantum Physics · Physics 2025-06-24 Mujahidul Islam , Serkan Turkeli , Fatih Ozaydin

Deep generative chemistry models emerge as powerful tools to expedite drug discovery. However, the immense size and complexity of the structural space of all possible drug-like molecules pose significant obstacles, which could be overcome…

Quantum Physics · Physics 2023-08-15 A. I. Gircha , A. S. Boev , K. Avchaciov , P. O. Fedichev , A. K. Fedorov

Generative adversarial network (GAN) is one of the widely-adopted machine-learning frameworks for a wide range of applications such as generating high-quality images, video, and audio contents. However, training a GAN could become…

Quantum Physics · Physics 2024-02-06 Runqiu Shu , Xusheng Xu , Man-Hong Yung , Wei Cui

Generative adversarial networks (GANs) represent a powerful tool for classical machine learning: a generator tries to create statistics for data that mimics those of a true data set, while a discriminator tries to discriminate between the…

Quantum Physics · Physics 2018-07-31 Seth Lloyd , Christian Weedbrook

Generative adversarial networks are an emerging technique with wide applications in machine learning, which have achieved dramatic success in a number of challenging tasks including image and video generation. When equipped with quantum…

Quantum machine learning is expected to be one of the first practical applications of near-term quantum devices. Pioneer theoretical works suggest that quantum generative adversarial networks (GANs) may exhibit a potential exponential…

Classical generative adversarial networks (GANs) have been applied to generate adversarial network traffic capable of attacking intrusion detection systems, but they suffer from shortcomings such as the need for large amounts of…

Machine Learning · Computer Science 2026-05-08 Prateek Paudel , Nitin Jha , Abhishek Parakh , Mahadevan Subramaniam

Generative adversarial networks (GANs) have achieved remarkable success with realistic tasks such as creating realistic images, texts, and audio. Combining GANs and quantum computing, quantum GANs are thought to have an exponential…

Quantum Physics · Physics 2024-12-04 Haoran Ma , Liao Ye , Fanjie Ruan , Zichao Zhao , Maohui Li , Yuehai Wang , Jianyi Yang
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