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Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms that discover network structure. In particular, a common goal…

Genomics · Quantitative Biology 2024-08-20 Niloofar Aghaieabiane , Ioannis Koutis

We present a new approach for the analysis of genome-wide expression data. Our method is designed to overcome the limitations of traditional techniques, when applied to large-scale data. Rather than alloting each gene to a single cluster,…

Biological Physics · Physics 2009-11-07 Sven Bergmann , Jan Ihmels , Naama Barkai

Facial expression recognition, as a vital computer vision task, is garnering significant attention and undergoing extensive research. Although facial expression recognition algorithms demonstrate impressive performance on high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Jingyi Shi

Accurately predicting gene expression from histopathology images offers a scalable and non-invasive approach to molecular profiling, with significant implications for precision medicine and computational pathology. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Yaxuan Song , Jianan Fan , Hang Chang , Weidong Cai

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

3D scene segmentation based on neural implicit representation has emerged recently with the advantage of training only on 2D supervision. However, existing approaches still requires expensive per-scene optimization that prohibits…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Hanlin Chen , Chen Li , Mengqi Guo , Zhiwen Yan , Gim Hee Lee

Scene graph generation (SGG) aims to detect objects and predict their pairwise relationships within an image. Current SGG methods typically utilize graph neural networks (GNNs) to acquire context information between objects/relationships.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Xin Lin , Changxing Ding , Yibing Zhan , Zijian Li , Dacheng Tao

Synthesizing consistent and photorealistic 3D scenes is an open problem in computer vision. Video diffusion models generate impressive videos but cannot directly synthesize 3D representations, i.e., lack 3D consistency in the generated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Katja Schwarz , Norman Mueller , Peter Kontschieder

Digital pathological analysis is run as the main examination used for cancer diagnosis. Recently, deep learning-driven feature extraction from pathology images is able to detect genetic variations and tumor environment, but few studies…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Haojie Huang , Gongming Zhou , Xuejun Liu , Lei Deng , Chen Wu , Dachuan Zhang , Hui Liu

Recently, there has been an increasing interest in image editing methods that employ pre-trained unconditional image generators (e.g., StyleGAN). However, applying these methods to translate images to multiple visual domains remains…

Computer Vision and Pattern Recognition · Computer Science 2022-03-07 Yahui Liu , Yajing Chen , Linchao Bao , Nicu Sebe , Bruno Lepri , Marco De Nadai

Selecting relevant features is an important and necessary step for intelligent machines to maximize their chances of success. However, intelligent machines generally have no enough computing resources when faced with huge volume of data.…

Machine Learning · Computer Science 2025-07-04 Hexiang Bai , Deyu Li , Jiye Liang , Yanhui Zhai

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

In this paper, we focus on image inpainting task, aiming at recovering the missing area of an incomplete image given the context information. Recent development in deep generative models enables an efficient end-to-end framework for image…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Yuhang Song , Chao Yang , Yeji Shen , Peng Wang , Qin Huang , C. -C. Jay Kuo

Spatial transcriptomics (ST) is a novel technology that enables the observation of gene expression at the resolution of individual spots within pathological tissues. ST quantifies the expression of tens of thousands of genes in a tissue…

Machine Learning · Computer Science 2025-11-25 Kaito Shiku , Kazuya Nishimura , Shinnosuke Matsuo , Yasuhiro Kojima , Ryoma Bise

Edge detection is typically viewed as a pixel-level classification problem mainly addressed by discriminative methods. Recently, generative edge detection methods, especially diffusion model based solutions, are initialized in the edge…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Caixia Zhou , Yaping Huang , Mochu Xiang , Jiahui Ren , Haibin Ling , Jing Zhang

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Self-supervised learning (SSL) has been successful in building patch embeddings of small histology images (e.g., 224x224 pixels), but scaling these models to learn slide embeddings from the entirety of giga-pixel whole-slide images (WSIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Guillaume Jaume , Lukas Oldenburg , Anurag Vaidya , Richard J. Chen , Drew F. K. Williamson , Thomas Peeters , Andrew H. Song , Faisal Mahmood

In this dissertation, we present a generative model to capture the relation between facial image quality features (like pose, illumination direction, etc) and face recognition performance. Such a model can be used to predict the performance…

Computer Vision and Pattern Recognition · Computer Science 2015-10-27 Abhishek Dutta

Human matting refers to extracting human parts from natural images with high quality, including human detail information such as hair, glasses, hat, etc. This technology plays an essential role in image synthesis and visual effects in the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-17 Qing Song , Wenfeng Sun , Donghan Yang , Mengjie Hu , Chun Liu