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Spatial transcriptomics (ST) bridges gene expression and tissue morphology but faces clinical adoption barriers due to technical complexity and prohibitive costs. While computational methods predict gene expression from H&E-stained…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ziqiao Weng , Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee AD Cooper , Weidong Cai , Bo Zhou

Pseudoprogression (PsP) is an imitation of true tumor progression (TTP) in patients with glioblastoma multiform (GBM). Differentiating them is a challenging and time-consuming task for radiologists. Although deep neural networks can…

Tissues and Organs · Quantitative Biology 2019-02-27 Xiaoming Liu , Michael D. Chan , Xiaobo Zhou , Xiaohua Qian

Machine learning-driven methods for property prediction have been of deep interest. However, much work remains to be done to improve the generalization ability, accuracy, and inference time for critical applications. The traditional machine…

Quantitative Methods · Quantitative Biology 2024-10-08 Kanad Sen , Saksham Gupta , Abhishek Raj , Alankar Alankar

Facial expression spotting is a significant but challenging task in facial expression analysis. The accuracy of expression spotting is affected not only by irrelevant facial movements but also by the difficulty of perceiving subtle motions…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Yicheng Deng , Hideaki Hayashi , Hajime Nagahara

Electrocardiograms (ECG) are widely employed as a diagnostic tool for monitoring electrical signals originating from a heart. Recent machine learning research efforts have focused on the application of screening various diseases using ECG…

Signal Processing · Electrical Eng. & Systems 2024-03-20 Yeongyeon Na , Minje Park , Yunwon Tae , Sunghoon Joo

Graph Neural Networks (GNNs) have received considerable attention since its introduction. It has been widely applied in various fields due to its ability to represent graph structured data. However, the application of GNNs is constrained by…

Neurons and Cognition · Quantitative Biology 2023-09-20 Yihan Wu , Tao Chang , Peng Xu , Yangsong Zhang

In recent years, there has been a rapid development of spatio-temporal prediction techniques in response to the increasing demands of traffic management and travel planning. While advanced end-to-end models have achieved notable success in…

Machine Learning · Computer Science 2023-11-09 Zhonghang Li , Lianghao Xia , Yong Xu , Chao Huang

Spatio-temporal area-level datasets play a critical role in official statistics, providing valuable insights for policy-making and regional planning. Accurate modeling and forecasting of these datasets can be extremely useful for…

Machine Learning · Computer Science 2026-01-06 Zhenhua Wang , Scott H. Holan , Christopher K. Wikle

Deep generative neural networks (DGNNs) have achieved realistic and high-quality data generation. In particular, the adversarial training scheme has been applied to many DGNNs and has exhibited powerful performance. Despite of recent…

Machine Learning · Computer Science 2019-12-13 Giyoung Jeon , Haedong Jeong , Jaesik Choi

Gene expression profiling provides profound insights into molecular mechanisms, but its time-consuming and costly nature often presents significant challenges. In contrast, whole-slide hematoxylin and eosin (H&E) stained histological images…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Ying Xiong , Linjing Liu , Yufei Cui , Shangyu Wu , Xue Liu , Antoni B. Chan , Chun Jason Xue

Electroencephalogram (EEG) technology, particularly high-density EEG (HD EEG) devices, is widely used in fields such as neuroscience. HD EEG devices improve the spatial resolution of EEG by placing more electrodes on the scalp, which meet…

Signal Processing · Electrical Eng. & Systems 2025-02-25 Shuqiang Wang , Tong Zhou , Yanyan Shen , Ye Li , Guoheng Huang , Yong Hu

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2018-01-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

In the majority of GAN architectures, the latent space is defined as a set of vectors of given dimensionality. Such representations are not easily interpretable and do not capture spatial information of image content directly. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Maciej Sypetkowski

In the domain of cardiovascular healthcare, the Electrocardiogram (ECG) serves as a critical, non-invasive diagnostic tool. Although recent strides in self-supervised learning (SSL) have been promising for ECG representation learning, these…

Signal Processing · Electrical Eng. & Systems 2023-09-15 Che Liu , Zhongwei Wan , Sibo Cheng , Mi Zhang , Rossella Arcucci

Generative modeling of anatomical structures plays a crucial role in virtual imaging trials, which allow researchers to perform studies without the costs and constraints inherent to in vivo and phantom studies. For clinical relevance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Bram de Wilde , Max T. Rietberg , Guillaume Lajoinie , Jelmer M. Wolterink

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Applications based on image retrieval require editing and associating in intermediate spaces that are representative of the high-level concepts like objects and their relationships rather than dense, pixel-level representations like RGB…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Rishi Agarwal , Tirupati Saketh Chandra , Vaidehi Patil , Aniruddha Mahapatra , Kuldeep Kulkarni , Vishwa Vinay

Epidemic forecasting is the key to effective control of epidemic transmission and helps the world mitigate the crisis that threatens public health. To better understand the transmission and evolution of epidemics, we propose EpiGNN, a graph…

Quantitative Methods · Quantitative Biology 2022-08-25 Feng Xie , Zhong Zhang , Liang Li , Bin Zhou , Yusong Tan

Accurately predicting the elastic properties of crystalline solids is vital for computational materials science. However, traditional atomistic scale ab initio approaches are computationally intensive, especially for studying complex…

Disordered Systems and Neural Networks · Physics 2023-11-13 Teerachote Pakornchote , Annop Ektarawong , Thiparat Chotibut

Symbolic Regression (SR) is a type of regression analysis to automatically find the mathematical expression that best fits the data. Currently, SR still basically relies on various searching strategies so that a sample-specific model is…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Jiachen Li , Ye Yuan , Hong-Bin Shen
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