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High-throughput chromatin conformation capture (Hi-C) data provide insights into the 3D structure of chromosomes, with normalization being a crucial pre-processing step. A common technique for normalization is matrix balancing, which…

Applications · Statistics 2025-06-17 John Park , Ning Hao , Yue Selena Niu , Ming Hu

Unfitted (also known as embedded or immersed) finite element approximations of partial differential equations are very attractive because they have much lower geometrical requirements than standard body-fitted formulations. These schemes do…

Numerical Analysis · Mathematics 2022-04-13 Santiago Badia , Pere A. Martorell , Francesc Verdugo

Black box variational inference allows researchers to easily prototype and evaluate an array of models. Recent advances allow such algorithms to scale to high dimensions. However, a central question remains: How to specify an expressive…

Machine Learning · Statistics 2016-06-01 Rajesh Ranganath , Dustin Tran , David M. Blei

In this note we extend the Differential Transfer Matrix Method (DTMM) for a second-order linear ordinary differential equation to the complex plane. This is achieved by separation of real and imaginary parts, and then forming a system of…

Mathematical Physics · Physics 2015-09-30 Sina Khorasani , Farhad Karimi

This paper introduces the hierarchical interpolative factorization for elliptic partial differential equations (HIF-DE) in two (2D) and three dimensions (3D). This factorization takes the form of an approximate generalized LU/LDL…

Numerical Analysis · Mathematics 2015-04-21 Kenneth L. Ho , Lexing Ying

This paper presents a general high-order kernel regularization technique applicable to all four integral operators of Calder\'on calculus associated with linear elliptic PDEs in two and three spatial dimensions. Like previous density…

Numerical Analysis · Mathematics 2021-03-02 Luiz M. Faria , Carlos Pérez-Arancibia , Marc Bonnet

Accurate simulations of atomistic systems from first principles are limited by computational cost. In high-throughput settings, machine learning can reduce these costs significantly by accurately interpolating between reference…

Chemical Physics · Physics 2022-11-28 Haoyan Huo , Matthias Rupp

Theoretical studies have proven that the Hilbert space has remarkable performance in many fields of applications. Frames in tensor product of Hilbert spaces were introduced to generalize the inner product to high-order tensors. However,…

Machine Learning · Statistics 2017-11-15 Yunfei Ye

In order to fully utilize "big data", it is often required to use "big models". Such models tend to grow with the complexity and size of the training data, and do not make strong parametric assumptions upfront on the nature of the…

Machine Learning · Statistics 2015-04-17 Vikas Sindhwani , Haim Avron

Hierarchical matrix approximations have gained significant traction in the machine learning and scientific community as they exploit available low-rank structures in kernel methods to compress the kernel matrix. The resulting compressed…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-03 Bangtian Liu , Kazem Cheshmi , Saeed Soori , Michelle Mills Strout , Maryam Mehri Dehnavi

We propose a novel framework for fast integral operations by uncovering hidden geometries in the row and column structures of the underlying operators. This is accomplished through the \texttt{Questionnaire} algorithm, an iterative…

Numerical Analysis · Mathematics 2026-02-27 Pei-Chun Su , Ronald R. Coifman

For a system of partial differential equations that has an extended Kovalevskaya form, a reduction procedure is presented that allows one to use a local (point, contact, or higher) symmetry of a system and a symmetry-invariant conservation…

Exactly Solvable and Integrable Systems · Physics 2026-03-16 Kostya Druzhkov , Alexei Cheviakov

This paper presents a new fast iterative solver for large systems involving kernel matrices. Advantageous aspects of H2 matrix approximations and the multigrid method are hybridized to create the H2-MG algorithm. This combination provides…

Numerical Analysis · Mathematics 2025-09-12 Daria Sushnikova , George Turkiyyah , Edmond Chow , David Keyes

Matrices with hierarchical low-rank structure, including HODLR and HSS matrices, constitute a versatile tool to develop fast algorithms for addressing large-scale problems. While existing software packages for such matrices often focus on…

Numerical Analysis · Mathematics 2020-01-30 Stefano Massei , Leonardo Robol , Daniel Kressner

Boundary element methods for the Helmholtz equation lead to large dense matrices that can only be handled if efficient compression techniques are used. Directional compression techniques can reach good compression rates even for…

Numerical Analysis · Mathematics 2020-11-03 Steffen Börm , Christina Börst

Hierarchical Matrix (H-matrix) is an approximation technique which splits a target dense matrix into multiple submatrices, and where a selected portion of submatrices are low-rank approximated. The technique substantially reduces both time…

Mathematical Software · Computer Science 2019-11-04 Rise Ooi , Takeshi Iwashita , Takeshi Fukaya , Akihiro Ida , Rio Yokota

We describe a new method to map the requested error tolerance on an H-matrix approximation to the block error tolerances. Numerical experiments show that the method produces more efficient approximations than the standard method for kernels…

Numerical Analysis · Mathematics 2011-10-14 Andrew M. Bradley

When modeling scientific and industrial problems, geometries are typically modeled by explicit boundary representations obtained from computer-aided design software. Unfitted (also known as embedded or immersed) finite element methods offer…

Computational Engineering, Finance, and Science · Computer Science 2024-05-24 Pere A. Martorell , Santiago Badia

The computation of homology groups for evolving simplicial complexes often requires repeated reconstruction of boundary operators, resulting in prohibitive costs for large-scale or frequently updated data. This work introduces MMHM, a…

Computational Geometry · Computer Science 2025-08-21 Anqiao Ouyang

Robust stability problem of integral delay systems with uncertain kernel matrix functions is addressed in this paper. On the basis of characteristic equation and the argument principle, an algorithm is generated which is shown to outperform…

Systems and Control · Electrical Eng. & Systems 2020-08-25 Hamed Taghavian