Related papers: Fiber Organization has Little Effect on Electrical…
One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be…
Knowledge of appropriate local fiber architecture is necessary to simulate patient-specific electromechanics in the human heart. However, it is not yet possible to reliably measure in-vivo fiber directions, especially in human atria. Thus,…
A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation are not feasible. Consequently, rule-based methods are…
The anisotropic structure of the myocardium is a key determinant of the cardiac function. To date, there is no imaging modality to assess in-vivo the cardiac fiber structure. We recently proposed Fibernet, a method for the automatic…
Electroanatomical maps are a key tool in the diagnosis and treatment of atrial fibrillation. Current approaches focus on the activation times recorded. However, more information can be extracted from the available data. The fibers in…
We propose FiberNet, a method to estimate \emph{in-vivo} the cardiac fiber architecture of the human atria from multiple catheter recordings of the electrical activation. Cardiac fibers play a central role in the electro-mechanical function…
Atrial arrhythmia can be categorized into tachycardia, flutter, and fibrillation. Atrial fibrillation is a prevalent heart disease that results in weak and irregular contractions of the atria. It affects millions people worldwide and…
Atrial fibrillation is a clinical arrhythmia with multifactorial mechanisms still unresolved. Time-frequency analysis of epicardial electrograms has been investigated to study atrial fibrillation. However, deeper understanding of atrial…
Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and…
Atrial Fibrillation (AF) is characterized by disorganised electrical activity in the atria and is known to be sustained by the presence of regions of fibrosis (scars) or functional cellular remodeling, both of which may lead to areas of…
Left ventricular torsion from helically oriented myofibers is a key parameter of cardiac performance. Physicians observing heart motion on echocardiograms, during cardiac catheterization, or in the operating room, are impressed by the…
Quantifying fiber disarray, which is a prominent maladaptation associated with hypertrophic cardiomyopathy, remains critical to understanding the disease's complex pathophysiology. This study investigates the role of heterogeneous…
Atrial fibrillation (AF) increases the risk of stroke by a factor of four to five and is the most common abnormal heart rhythm. The progression of AF with age, from short self-terminating episodes to persistence, varies between individuals…
We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…
The mechanism of atrial fibrillation (AF) is poorly understood, resulting in disappointing success rates of ablative treatment. Different mechanisms defined largely by different atrial activation patterns have been proposed and, arguably,…
Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from…
We study the interplay between traveling action potentials and spatial inhomogeneities in the FitzHugh-Nagumo model to investigate possible mechanisms for the occurrence of fibrillatory states in the atria of the heart. Different dynamical…
Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomical…
The deformation of the left atrium (LA), or its biomechanical function, is closely linked to the health of this cardiac chamber. In atrial fibrillation (AF), atrial biomechanics are significantly altered but the underlying cause of this…
In this work we propose a mathematical model that describes the orientation of ventricular cardiac fibers. These fibers are commonly computed as the normalized gradient of certain harmonic potentials, so our work consisted in finding the…