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This paper is a part of a student project in Machine Learning at the Norwegian University of Science and Technology. In this paper, a deep convolutional neural network with five convolutional layers and three fully-connected layers is…
This work proposes a way to detect the wandering activity of Alzheimer's patients from path data collected from non-intrusive indoor sensors around the house. Due to the lack of adequate data, we've manually generated a dataset of 220 paths…
Deep convolutional neural networks (CNNs) trained on objects and scenes have shown intriguing ability to predict some response properties of visual cortical neurons. However, the factors and computations that give rise to such ability, and…
Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…
The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…
Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…
Prediction the conversion to early-stage dementia is critical for mitigating its progression but remains challenging due to subtle cognitive impairments and structural brain changes. Traditional T1-weighted magnetic resonance imaging…
Using multimodal neuroimaging data to characterize brain network is currently an advanced technique for Alzheimer's disease(AD) Analysis. Over recent years the neuroimaging community has made tremendous progress in the study of…
INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…
Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…
Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…
Efforts are underway to study ways via which the power of deep neural networks can be extended to non-standard data types such as structured data (e.g., graphs) or manifold-valued data (e.g., unit vectors or special matrices). Often,…
Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…
To understand multifactorial conditions such as Alzheimers disease (AD) we need brain signatures that predict the impact of multiple pathologies and their interactions. To help uncover the relationships between brain circuits and cognitive…
Dendrites are crucial structures for computation of an individual neuron. It has been shown that the dynamics of a biological neuron with dendrites can be approximated by artificial neural networks (ANN) with deep structure. However, it…
Bayesian neural network models (BNN) have re-surged in recent years due to the advancement of scalable computations and its utility in solving complex prediction problems in a wide variety of applications. Despite the popularity and…
Alzheimer's disease (AD) is the most common age-related dementia. It remains a challenge to identify the individuals at risk of dementia for precise management. Brain MRI offers a noninvasive biomarker to detect brain aging. Previous…
Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through…
Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…
Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…