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Neuroscientists fit morphologically and biophysically detailed neuron simulations to physiological data, often using evolutionary algorithms. However, such gradient-free approaches are computationally expensive, making convergence slow when…

Neurons and Cognition · Quantitative Biology 2024-07-23 Ilenna Simone Jones , Konrad Paul Kording

Robust machine learning is currently one of the most prominent topics which could potentially help shaping a future of advanced AI platforms that not only perform well in average cases but also in worst cases or adverse situations. Despite…

Computer Vision and Pattern Recognition · Computer Science 2019-12-06 Pu Zhao , Sijia Liu , Pin-Yu Chen , Nghia Hoang , Kaidi Xu , Bhavya Kailkhura , Xue Lin

The dual challenges of prohibitive communication overhead and the impracticality of gradient computation due to data privacy or black-box constraints in distributed systems motivate this work on communication-constrained gradient-free…

Optimization and Control · Mathematics 2025-09-19 Youqing Hua , Shuai Liu , Yiguang Hong , Wei Ren

Electron cryomicroscopy (cryo-EM) is an imaging technique widely used in structural biology to determine the three-dimensional structure of biological molecules from noisy two-dimensional projections with unknown orientations. As the…

Numerical Analysis · Mathematics 2025-06-26 Bogdan Toader , Marcus A. Brubaker , Roy R. Lederman

This paper considers a consensus optimization problem, where all the nodes in a network, with access to the zeroth-order information of its local objective function only, attempt to cooperatively achieve a common minimizer of the sum of…

Optimization and Control · Mathematics 2024-06-17 Chengan Wang , Zichong Ou , Jie Lu

Stochastic gradient descent (SGD) method is popular for solving non-convex optimization problems in machine learning. This work investigates SGD from a viewpoint of graduated optimization, which is a widely applied approach for non-convex…

Optimization and Control · Mathematics 2023-08-15 Da Li , Jingjing Wu , Qingrun Zhang

Automation is one of the cornerstones of contemporary material discovery. Bayesian optimization (BO) is an essential part of such workflows, enabling scientists to leverage prior domain knowledge into efficient exploration of a large…

Machine Learning · Computer Science 2024-05-30 Agustinus Kristiadi , Felix Strieth-Kalthoff , Marta Skreta , Pascal Poupart , Alán Aspuru-Guzik , Geoff Pleiss

Zeroth-order optimization (ZO) is widely used for solving black-box optimization and control problems. In particular, single-point ZO (SZO) is well-suited to online or dynamic problem settings due to its requirement of only a single…

Optimization and Control · Mathematics 2026-02-06 Xin Chen , Zhaolin Ren

Large language models (LLMs) have brought about significant transformations in human society. Among the crucial computations in LLMs, the softmax unit holds great importance. Its helps the model generating a probability distribution on…

Machine Learning · Computer Science 2023-07-18 Yichuan Deng , Zhihang Li , Sridhar Mahadevan , Zhao Song

In this paper, we prove new complexity bounds for zeroth-order methods in non-convex optimization with inexact observations of the objective function values. We use the Gaussian smoothing approach of Nesterov and Spokoiny [2015] and extend…

Optimization and Control · Mathematics 2021-01-14 Innokentiy Shibaev , Pavel Dvurechensky , Alexander Gasnikov

We consider a distributed convex optimization problem in a network which is time-varying and not always strongly connected. The local cost function of each node is affected by some stochastic process. All nodes of the network collaborate to…

Optimization and Control · Mathematics 2021-05-27 Wenjie Li , Mohamad Assaad

Stochastic First-Order (SFO) methods have been a cornerstone in addressing a broad spectrum of modern machine learning (ML) challenges. However, their efficacy is increasingly questioned, especially in large-scale applications where…

Machine Learning · Computer Science 2024-08-01 Di Zhang , Suvrajeet Sen

Zeroth-order optimization (ZO) typically relies on two-point feedback to estimate the unknown gradient of the objective function. Nevertheless, two-point feedback can not be used for online optimization of time-varying objective functions,…

Machine Learning · Computer Science 2020-12-04 Yan Zhang , Yi Zhou , Kaiyi Ji , Michael M. Zavlanos

Gradient-free optimizers allow for tackling problems regardless of the smoothness or differentiability of their objective function, but they require many more iterations to converge when compared to gradient-based algorithms. This has made…

Machine Learning · Computer Science 2024-09-24 Gawel Kus , Miguel A. Bessa

Neural network optimization remains one of the most consequential yet poorly understood challenges in modern AI research, where improvements in training algorithms can lead to enhanced feature learning in foundation models,…

Machine Learning · Computer Science 2025-12-23 Ansh Nagwekar

Zeroth-order (ZO) optimization provides a powerful framework for problems where explicit gradients are unavailable and have to be approximated using only queries to function value. The prevalent single-query approach is simple, but suffers…

Machine Learning · Computer Science 2026-02-03 Wei Lin , Qingyu Song , Hong Xu

Geometry optimization is an important task in quantum chemical calculations to analyze the characteristics of molecules. A top concern on it is a long execution time because time-consuming energy and gradient calculations are repeated…

Chemical Physics · Physics 2024-04-22 Satoshi Imamura , Akihiko Kasagi , Eiji Yoshida

Comparison-Based Optimization (CBO) is an optimization paradigm that assumes only very limited access to the objective function f(x). Despite the growing relevance of CBO to real-world applications, this field has received little attention…

Optimization and Control · Mathematics 2023-03-27 Isha Slavin , Daniel McKenzie

This paper considers zeroth-order optimization for stochastic convex minimization problem. We propose a parameter-free stochastic zeroth-order method (POEM) by introducing a step-size scheme based on the distance over finite difference and…

Optimization and Control · Mathematics 2025-05-06 Kunjie Ren , Luo Luo

Incentive-based load curtailment unlocks critical demand-side flexibility but is hindered by the limited knowledge of private user parameters and the inherent nonsmoothness of responses due to physical device constraints. We address this…

Systems and Control · Electrical Eng. & Systems 2026-05-27 Zhisen Jiang , Florian Dörfler , Saverio Bolognani