English
Related papers

Related papers: Understanding Adverse Biological Effect Prediction…

200 papers

With the continuous growth of large Knowledge Graphs (KGs), extractive KG summarization becomes a trending task. Aiming at distilling a compact subgraph with condensed information, it facilitates various downstream KG-based tasks. In this…

Artificial Intelligence · Computer Science 2024-02-20 Xiaxia Wang , Gong Cheng

Leveraging domain knowledge including fingerprints and functional groups in molecular representation learning is crucial for chemical property prediction and drug discovery. When modeling the relation between graph structure and molecular…

Machine Learning · Computer Science 2021-03-25 Yin Fang , Haihong Yang , Xiang Zhuang , Xin Shao , Xiaohui Fan , Huajun Chen

In recent years, we have witnessed the proliferation of knowledge graphs (KG) in various domains, aiming to support applications like question answering, recommendations, etc. A frequent task when integrating knowledge from different KGs is…

Databases · Computer Science 2023-06-08 Nikolaos Fanourakis , Vasilis Efthymiou , Dimitris Kotzinos , Vassilis Christophides

We report a deep generative model for regression tasks in materials informatics. The model is introduced as a component of a data imputer, and predicts more than 20 diverse experimental properties of organic molecules. The imputer is…

Computational Physics · Physics 2021-03-02 Kan Hatakeyama-Sato , Kenichi Oyaizu

NLP systems have shown impressive performance at answering questions by retrieving relevant context. However, with the increasingly large models, it is impossible and often undesirable to constrain models' knowledge or reasoning to only the…

Computation and Language · Computer Science 2023-10-27 Navita Goyal , Eleftheria Briakou , Amanda Liu , Connor Baumler , Claire Bonial , Jeffrey Micher , Clare R. Voss , Marine Carpuat , Hal Daumé

Large-scale knowledge graphs (KGs) are shown to become more important in current information systems. To expand the coverage of KGs, previous studies on knowledge graph completion need to collect adequate training instances for newly-added…

Computation and Language · Computer Science 2020-01-09 Pengda Qin , Xin Wang , Wenhu Chen , Chunyun Zhang , Weiran Xu , William Yang Wang

Knowledge Graphs (KGs), composed of triples in the form of (head, relation, tail) and consisting of entities and relations, play a key role in information retrieval systems such as question answering, entity search, and recommendation. In…

Artificial Intelligence · Computer Science 2025-05-13 Jeongho Kim , Chanyeong Heo , Jaehee Jung

Drug Side-Effects (DSEs) have a high impact on public health, care system costs, and drug discovery processes. Predicting the probability of side-effects, before their occurrence, is fundamental to reduce this impact, in particular on drug…

Quantitative Methods · Quantitative Biology 2022-02-17 Pietro Bongini , Franco Scarselli , Monica Bianchini , Giovanna Maria Dimitri , Niccolò Pancino , Pietro Liò

Optimizing chemical properties is a challenging task due to the vastness and complexity of chemical space. Here, we present a generative energy-based architecture for implicit chemical property optimization, designed to efficiently generate…

Biomolecules · Quantitative Biology 2025-06-19 Luca Miglior , Lorenzo Simone , Marco Podda , Davide Bacciu

Drug-drug interactions (DDIs) remain a major source of preventable harm, and many clinically important mechanisms are still unknown. Existing models either rely on pharmacologic knowledge graphs (KGs), which fail on unseen drugs, or on…

Machine Learning · Computer Science 2025-11-11 Franklin Lee , Tengfei Ma

Knowledge Graphs (KGs) have been utilized as useful side information to improve recommendation quality. In those recommender systems, knowledge graph information often contains fruitful facts and inherent semantic relatedness among items.…

Information Retrieval · Computer Science 2022-08-19 Yuhao Yang , Chao Huang , Lianghao Xia , Chenliang Li

Scientific inquiry requires systems-level reasoning that integrates heterogeneous experimental data, cross-domain knowledge, and mechanistic evidence into coherent explanations. While Large Language Models (LLMs) offer inferential…

Artificial Intelligence · Computer Science 2026-01-09 Isabella A. Stewart , Markus J. Buehler

Clinical predictive models often rely on patients' electronic health records (EHR), but integrating medical knowledge to enhance predictions and decision-making is challenging. This is because personalized predictions require personalized…

Artificial Intelligence · Computer Science 2024-01-19 Pengcheng Jiang , Cao Xiao , Adam Cross , Jimeng Sun

The knowledge graph(KG) composed of entities with their descriptions and attributes, and relationship between entities, is finding more and more application scenarios in various natural language processing tasks. In a typical knowledge…

Computation and Language · Computer Science 2018-10-15 Shengjie Sun , Dong Yang , Hongchun Zhang , Yanxu Chen , Chao Wei , Xiaonan Meng , Yi Hu

Knowledge Graphs (KGs) are a major asset for companies thanks to their great flexibility in data representation and their numerous applications, e.g., vocabulary sharing, Q/A or recommendation systems. To build a KG it is a common practice…

Artificial Intelligence · Computer Science 2024-07-22 Lucas Jarnac , Yoan Chabot , Miguel Couceiro

In the evolving field of psychopathology, the accurate assessment and forecasting of data derived from Ecological Momentary Assessment (EMA) is crucial. EMA offers contextually-rich psychopathological measurements over time, that…

Machine Learning · Computer Science 2024-03-29 Mandani Ntekouli , Gerasimos Spanakis , Lourens Waldorp , Anne Roefs

Recent years have witnessed the significant damage caused by various types of fake news. Although considerable effort has been applied to address this issue and much progress has been made on detecting fake news, most existing approaches…

Social and Information Networks · Computer Science 2021-08-11 Yi Han , Amila Silva , Ling Luo , Shanika Karunasekera , Christopher Leckie

To provide more accurate, diverse, and explainable recommendation, it is compulsory to go beyond modeling user-item interactions and take side information into account. Traditional methods like factorization machine (FM) cast it as a…

Machine Learning · Computer Science 2019-06-11 Xiang Wang , Xiangnan He , Yixin Cao , Meng Liu , Tat-Seng Chua

Despite the recent popularity of knowledge graph (KG) related tasks and benchmarks such as KG embeddings, link prediction, entity alignment and evaluation of the reasoning abilities of pretrained language models as KGs, the structure and…

Machine Learning · Computer Science 2023-11-14 Nedelina Teneva , Estevam Hruschka

Temporal Knowledge Graph (TKG) completion models traditionally assume access to the entire graph during training. This overlooks challenges stemming from the evolving nature of TKGs, such as: (i) the model's requirement to generalize and…

Artificial Intelligence · Computer Science 2025-07-28 Mehrnoosh Mirtaheri , Ryan A. Rossi , Sungchul Kim , Kanak Mahadik , Tong Yu , Xiang Chen , Mohammad Rostami