Related papers: Brain Modeling for Control: A Review
Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…
Brain stimulation is a powerful tool for understanding cortical function and holds promise for therapeutic interventions in neuropsychiatric disorders. Initial visual prosthetics apply electric microstimulation to early visual cortex which…
A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…
This paper investigates the controllability of a broad class of recurrent neural networks widely used in theoretical neuroscience, including models of large-scale human brain dynamics. Motivated by emerging applications in non-invasive…
Over the past decade, techniques enabling bidirectional modulation of neuronal activity with single cell precision have rapidly advanced in the form of two-photon optogenetic stimulation. Unlike conventional electrophysiological approaches…
Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…
Conventional deep brain stimulation (DBS) of basal ganglia uses high-frequency regular electrical pulses to treat Parkinsonian motor symptoms and has a series of limitations. Relatively new and not yet clinically tested optogenetic…
The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…
Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…
The study involved 56 patients with advanced and late stages of Parkinsons disease, which could be considered as potentially requiring neurosurgical treatment-electrical stimulation of deep brain structures. An algorithm has been developed…
Parkinson's Disease afflicts millions of individuals globally. Emerging as a promising brain rehabilitation therapy for Parkinson's Disease, Closed-loop Deep Brain Stimulation (CL-DBS) aims to alleviate motor symptoms. The CL-DBS system…
Stylized models of the neurodynamics that underpin sensory motor control in animals are proposed and studied. The voluntary motions of animals are typically initiated by high level intentions created in the primary cortex through a…
At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…
Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…
The brain stimulation and its widespread use is one of the most important subjects in studies of neurophysiology. In brain electrical stimulation methods, following the surgery and electrode implantation, electrodes send electrical impulses…
The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…
Closed-loop neural stimulation provides novel therapies for neurological diseases such as Parkinson's disease (PD), but it is not yet clear whether artificial intelligence (AI) techniques can tailor closed-loop stimulation to individual…
The way the brain selects and controls actions is still widely debated. Mainstream approaches based on Optimal Control focus on stimulus-response mappings that optimize cost functions. Ideomotor theory and cybernetics propose a different…
Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…
Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…