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The use of artificial intelligence (AI) in automated disease classification significantly reduces healthcare costs and improves the accessibility of services. However, this transformation has given rise to concerns about the fairness of AI,…

Machine Learning · Computer Science 2024-12-04 Leila Gheisi , Henry Chu , Raju Gottumukkala , Yan Luo , Xingquan Zhu , Mengyu Wang , Min Shi

The increased adoption of Electronic Health Records(EHRs) has brought changes to the way the patient care is carried out. The rich heterogeneous and temporal data space stored in EHRs can be leveraged by machine learning models to capture…

Machine Learning · Computer Science 2019-04-11 Maria Bampa

Recent advancements in large language models have demonstrated their potential in numerous medical applications, particularly in automating clinical trial matching for translational research and enhancing medical question answering for…

Computation and Language · Computer Science 2024-10-15 Yuelyu Ji , Wenhe Ma , Sonish Sivarajkumar , Hang Zhang , Eugene Mathew Sadhu , Zhuochun Li , Xizhi Wu , Shyam Visweswaran , Yanshan Wang

Unobserved confounding is a fundamental challenge for estimating causal effects. To address unobserved confounding, recent literature has turned to two different approaches -- proxy variables and the use of multiple treatments. The first…

Methodology · Statistics 2026-05-20 Aytijhya Saha , Stephen Bates , Devavrat Shah

We introduce HTAD, a novel model for diagnosis prediction using Electronic Health Records (EHR) represented as Heterogeneous Information Networks. Recent studies on modeling EHR have shown success in automatically learning representations…

Machine Learning · Computer Science 2019-12-24 Anahita Hosseini , Tyler Davis , Majid Sarrafzadeh

The wide implementation of electronic health record (EHR) systems facilitates the collection of large-scale health data from real clinical settings. Despite the significant increase in adoption of EHR systems, this data remains largely…

Quantitative Methods · Quantitative Biology 2018-10-26 Jinghe Zhang , Kamran Kowsari , James H. Harrison , Jennifer M. Lobo , Laura E. Barnes

Electronic health record (EHR) management systems require the adoption of effective technologies when health information is being exchanged. Current management approaches often face risks that may expose medical record storage solutions to…

Cryptography and Security · Computer Science 2021-01-28 Charalampos Stamatellis , Pavlos Papadopoulos , Nikolaos Pitropakis , Sokratis Katsikas , William J Buchanan

Objective: Temporal electronic health records (EHRs) can be a wealth of information for secondary uses, such as clinical events prediction or chronic disease management. However, challenges exist for temporal data representation. We…

Machine Learning · Computer Science 2024-06-11 Feng Xie , Han Yuan , Yilin Ning , Marcus Eng Hock Ong , Mengling Feng , Wynne Hsu , Bibhas Chakraborty , Nan Liu

Protecting patient privacy remains a fundamental barrier to scaling machine learning across healthcare institutions, where centralizing sensitive data is often infeasible due to ethical, legal, and regulatory constraints. Federated learning…

Machine Learning · Computer Science 2026-03-24 Vagish Kumar , Syed Bahauddin Alam , Souvik Chakraborty

Models notoriously suffer from dataset biases which are detrimental to robustness and generalization. The identify-emphasize paradigm shows a promising effect in dealing with unknown biases. However, we find that it is still plagued by two…

Machine Learning · Computer Science 2022-11-29 Bowen Zhao , Chen Chen , Qian-Wei Wang , Anfeng He , Shu-Tao Xia

No unmeasured confounding is often assumed in estimating treatment effects in observational data when using approaches such as propensity scores and inverse probability weighting. However, in many such studies due to the limitation of the…

Applications · Statistics 2019-08-06 Rong Huang , Ronghui Xu , Parambir S. Dulai

Linear Discriminant Analysis (LDA) is a well-known technique for feature extraction and dimension reduction. The performance of classical LDA, however, significantly degrades on the High Dimension Low Sample Size (HDLSS) data for the…

Machine Learning · Computer Science 2023-03-09 Sijia Yang , Haoyi Xiong , Kaibo Xu , Licheng Wang , Jiang Bian , Zeyi Sun

Healthcare disparities persist across socioeconomic boundaries, often attributed to unequal access to screening, diagnostics, and therapeutics. However, this perspective highlights that critical biases can emerge much earlier, during data…

Artificial Intelligence · Computer Science 2026-04-17 Michal Rosen-Zvi , Yoav Kan-Tor , Michael Danziger , Agata Ferretti , Javier Aula-Blasco , Julia Falcao , Ron Shamir , Mordechai Muszkat

Recent work in machine learning for healthcare has raised concerns about patient privacy and algorithmic fairness. For example, previous work has shown that patient self-reported race can be predicted from medical data that does not…

Machine Learning · Computer Science 2023-11-14 Wei Liao , Joel Voldman

Identification of treatment effects in the presence of unmeasured confounding is a persistent problem in the social, biological, and medical sciences. The problem of unmeasured confounding in settings with multiple treatments is most common…

Methodology · Statistics 2022-07-12 Wang Miao , Wenjie Hu , Elizabeth L. Ogburn , Xiaohua Zhou

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

Computers and Society · Computer Science 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

Recently, there has been a lot of interest in ensuring algorithmic fairness in machine learning where the central question is how to prevent sensitive information (e.g. knowledge about the ethnic group of an individual) from adding "unfair"…

Machine Learning · Computer Science 2020-05-19 Aarsh Patel , Rahul Gupta , Mukund Harakere , Satyapriya Krishna , Aman Alok , Peng Liu

Missing data is a common concern in health datasets, and its impact on good decision-making processes is well documented. Our study's contribution is a methodology for tackling missing data problems using a combination of synthetic dataset…

Machine Learning · Computer Science 2022-11-08 Gift Khangamwa , Terence L. van Zyl , Clint J. van Alten

In many social, behavioral, and biomedical sciences, treatment effect estimation is a crucial step in understanding the impact of an intervention, policy, or treatment. In recent years, an increasing emphasis has been placed on…

Methodology · Statistics 2024-10-10 Xinhai Zhang , Xingye Qiao

Electronic health records (EHRs) are increasingly used for clinical and comparative effectiveness research, but suffer from missing data. Motivated by health services research on diabetes care, we seek to increase the quality of EHRs by…

Methodology · Statistics 2020-07-14 Yajuan Si , Mari Palta , Maureen Smith