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Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Minkyu Jeon , Rishwanth Raghu , Miro Astore , Geoffrey Woollard , Ryan Feathers , Alkin Kaz , Sonya M. Hanson , Pilar Cossio , Ellen D. Zhong

This work investigates the problem of signal recovery from undersampled noisy sub-Gaussian measurements under the assumption of a synthesis-based sparsity model. Solving the $\ell^1$-synthesis basis pursuit allows for a simultaneous…

Information Theory · Computer Science 2020-04-16 Maximilian März , Claire Boyer , Jonas Kahn , Pierre Weiss

This paper develops a novel algorithm, termed \emph{SPARse Truncated Amplitude flow} (SPARTA), to reconstruct a sparse signal from a small number of magnitude-only measurements. It deals with what is also known as sparse phase retrieval…

Information Theory · Computer Science 2017-10-31 Gang Wang , Liang Zhang , Georgios B. Giannakis , Mehmet Akcakaya , Jie Chen

In this work, we introduce a novel approach for determining a joint sparse spectrum from several non-uniformly sampled data sets, where each data set is assumed to have its own, possibly disjoint, and only partially known, sampling times.…

Signal Processing · Electrical Eng. & Systems 2021-10-07 David Svedberg , Filip Elvander , Andreas Jakobsson

Cryo-electron microscopy (cryo-EM), the subject of the 2017 Nobel Prize in Chemistry, is a technology for determining the 3-D structure of macromolecules from many noisy 2-D projections of instances of these macromolecules, whose…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Roy R. Lederman , Joakim Andén , Amit Singer

We revisit the topic of common lines between projection images in single particle cryo-electron microscopy (cryo-EM). We derive a novel low-rank constraint on a certain $2n \times n$ matrix storing properly-scaled basis vectors for the…

Optimization and Control · Mathematics 2024-06-10 Tommi Muller , Adriana L. Duncan , Eric J. Verbeke , Joe Kileel

Different tasks in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM) require enhancing the quality of the highly noisy raw images. To this end, we develop an efficient algorithm for signal enhancement of…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Guy Sharon , Yoel Shkolnisky , Tamir Bendory

A major challenge in single-particle cryo-electron microscopy (cryo-EM) is that the orientations adopted by the 3D particles prior to imaging are unknown; yet, this knowledge is essential for high-resolution reconstruction. We present a…

Machine Learning · Computer Science 2021-04-14 Jelena Banjac , Laurène Donati , Michaël Defferrard

While ordinary differential equations (ODEs) form the conceptual framework for modelling many cellular processes, specific situations demand stochastic models to capture the influence of noise. The most common formulation of stochastic…

Subcellular Processes · Quantitative Biology 2009-04-02 Mukhtar Ullah , Olaf Wolkenhauer

Rotation averaging (RA) is a fundamental problem in robotics and computer vision. In RA, the goal is to estimate a set of $N$ unknown orientations $R_{1}, ..., R_{N} \in SO(3)$, given noisy measurements $R_{ij} \sim R^{-1}_{i} R_{j}$ of a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Owen Howell , Haoen Huang , David Rosen

Parameter estimation from multiple measurement vectors (MMVs) is a fundamental problem in many signal processing applications, e.g., spectral analysis and direction-of- arrival estimation. Recently, this problem has been address using prior…

Information Theory · Computer Science 2016-06-24 Christian Steffens , Marius Pesavento , Marc E. Pfetsch

Motivated by applications to single-particle cryo-electron microscopy (cryo-EM), we study several problems of function estimation in a high noise regime, where samples are observed after random rotation and possible linear projection of the…

Statistics Theory · Mathematics 2022-10-06 Zhou Fan , Roy R. Lederman , Yi Sun , Tianhao Wang , Sheng Xu

In the Multiple Measurements Vector (MMV) model, measurement vectors are connected to unknown, jointly sparse signal vectors through a linear regression model employing a single known measurement matrix (or dictionary). Typically, the…

Methodology · Statistics 2024-08-05 Esa Ollila

We consider the two-dimensional multi-target detection problem of recovering a target image from a noisy measurement that contains multiple copies of the image, each randomly rotated and translated. Motivated by the structure reconstruction…

Signal Processing · Electrical Eng. & Systems 2022-05-17 Shay Kreymer , Tamir Bendory

We consider the problem of exact support recovery of sparse signals via noisy measurements. The main focus is the sufficient and necessary conditions on the number of measurements for support recovery to be reliable. By drawing an analogy…

Information Theory · Computer Science 2010-03-04 Yuzhe Jin , Young-Han Kim , Bhaskar D. Rao

In this paper we revisit the sparse multiple measurement vector (MMV) problem where the aim is to recover a set of jointly sparse multichannel vectors from incomplete measurements. This problem has received increasing interest as an…

Information Theory · Computer Science 2015-03-14 Mike E. Davies , Yonina C. Eldar

Spherical microphone arrays (SMAs) are widely used for sound field analysis, and sparse recovery (SR) techniques can significantly enhance their spatial resolution by modeling the sound field as a sparse superposition of dominant plane…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-05 Shunxi Xu , Craig T. Jin

The problem of estimating a sparse signal from low dimensional noisy observations arises in many applications, including super resolution, signal deconvolution, and radar imaging. In this paper, we consider a sparse signal model with…

Information Theory · Computer Science 2020-06-24 Youye Xie , Michael B. Wakin , Gongguo Tang

In this paper, we discuss application of iterative Stochastic Optimization routines to the problem of sparse signal recovery from noisy observation. Using Stochastic Mirror Descent algorithm as a building block, we develop a multistage…

Machine Learning · Statistics 2022-03-31 Anatoli Juditsky , Andrei Kulunchakov , Hlib Tsyntseus

Because optical systems have huge bandwidth and are capable of generating low noise short pulses they are ideal for undersampling multi-band signals that are located within a very broad frequency range. In this paper we propose a new scheme…

Optics · Physics 2009-11-13 Amir Rosenthal , Alex Linden , Moshe Horowitz
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