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Understanding the causal effects of text on downstream outcomes is a central task in many applications. Estimating such effects requires researchers to run controlled experiments that systematically vary textual features. While large…

Computation and Language · Computer Science 2026-02-18 Omri Feldman , Amar Venugopal , Jann Spiess , Amir Feder

Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route to understanding how perturbations reshape cellular…

Machine Learning · Computer Science 2026-05-26 Wenkang Jiang , Yuhang Liu , Erdun Gao , Ehsan Abbasnejad , Lina Yao , Javen Qinfeng Shi

Causal graph recovery is traditionally done using statistical estimation-based methods or based on individual's knowledge about variables of interests. They often suffer from data collection biases and limitations of individuals' knowledge.…

Computation and Language · Computer Science 2024-06-19 Yuzhe Zhang , Yipeng Zhang , Yidong Gan , Lina Yao , Chen Wang

Claiming causal inferences in network settings necessitates careful consideration of the often complex dependency between outcomes for actors. Of particular importance are treatment spillover or outcome interference effects. We consider…

Methodology · Statistics 2022-07-18 Duncan A. Clark , Mark S. Handcock

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Causal discovery can be computationally demanding for large numbers of variables. If we only wish to estimate the causal effects on a small subset of target variables, we might not need to learn the causal graph for all variables, but only…

Machine Learning · Statistics 2025-02-13 Mátyás Schubert , Tom Claassen , Sara Magliacane

Selective inference (post-selection inference) is a methodology that has attracted much attention in recent years in the fields of statistics and machine learning. Naive inference based on data that are also used for model selection tends…

Methodology · Statistics 2021-11-25 Yoshiyuki Ninomiya , Yuta Umezu , Ichiro Takeuchi

We address the problem of causal effect estimation where hidden confounders are present, with a focus on two settings: instrumental variable regression with additional observed confounders, and proxy causal learning. Our approach uses a…

Machine Learning · Computer Science 2025-03-12 Haotian Sun , Antoine Moulin , Tongzheng Ren , Arthur Gretton , Bo Dai

Predicting the impact of genomic and drug perturbations in cellular function is crucial for understanding gene functions and drug effects, ultimately leading to improved therapies. To this end, Causal Representation Learning (CRL)…

To draw scientifically meaningful conclusions and build reliable models of quantitative phenomena, cause and effect must be taken into consideration (either implicitly or explicitly). This is particularly challenging when the measurements…

Machine Learning · Computer Science 2020-12-11 Max A. Little , Reham Badawy

Causal representation learning seeks to uncover causal relationships among high-level latent variables from low-level, entangled, and noisy observations. Existing approaches often either rely on deep neural networks, which lack…

Methodology · Statistics 2026-03-27 Wenjin Zhang , Yixin Wang , Yuqi Gu

This paper develops a framework for identification, estimation, and inference on the causal mechanisms driving endogenous social network formation. Identification is challenging because of unobserved confounders and reverse causality;…

Econometrics · Economics 2026-04-21 Maximilian Kasy , Elizabeth Linos , Sanaz Mobasseri

Current supervised learning can learn spurious correlation during the data-fitting process, imposing issues regarding interpretability, out-of-distribution (OOD) generalization, and robustness. To avoid spurious correlation, we propose a…

Machine Learning · Computer Science 2021-04-29 Xinwei Sun , Botong Wu , Xiangyu Zheng , Chang Liu , Wei Chen , Tao Qin , Tie-yan Liu

Using deep latent variable models in causal inference has attracted considerable interest recently, but an essential open question is their ability to yield consistent causal estimates. While they have demonstrated promising results and…

Machine Learning · Computer Science 2022-01-25 Severi Rissanen , Pekka Marttinen

This paper studies causal discovery in irregularly sampled time series-a key challenge in risk-sensitive domains like finance, healthcare, and climate science, where missing data and inconsistent sampling frequencies distort causal…

Machine Learning · Computer Science 2026-05-12 Weihong Li , Baohong Li , Anpeng Wu , Zhihan Li , Ming Ma , Keting Yin , Kun Kuang

Local causal structure learning aims to discover and distinguish direct causes (parents) and direct effects (children) of a variable of interest from data. While emerging successes have been made, existing methods need to search a large…

Artificial Intelligence · Computer Science 2021-01-12 Shuai Yang , Hao Wang , Kui Yu , Fuyuan Cao , Xindong Wu

Due to a wide spectrum of applications in the real world, such as security, financial surveillance, and health risk, various deep anomaly detection models have been proposed and achieved state-of-the-art performance. However, besides being…

Machine Learning · Computer Science 2023-09-08 Xiao Han , Lu Zhang , Yongkai Wu , Shuhan Yuan

When causal quantities cannot be point identified, researchers often pursue partial identification to quantify the range of possible values. However, the peculiarities of applied research conditions can make this analytically intractable.…

Methodology · Statistics 2021-09-29 Guilherme Duarte , Noam Finkelstein , Dean Knox , Jonathan Mummolo , Ilya Shpitser

We develop a criterion to certify whether causal effects are identifiable in linear structural equation models with latent variables. Linear structural equation models correspond to directed graphs whose nodes represent the random variables…

Statistics Theory · Mathematics 2025-07-25 Nils Sturma , Mathias Drton

Causal effect estimation (CEE) provides a crucial tool for predicting the unobserved counterfactual outcome for an entity. As CEE relaxes the requirement for ``perfect'' counterfactual samples (e.g., patients with identical attributes and…

Machine Learning · Computer Science 2024-11-19 Hechuan Wen , Tong Chen , Guanhua Ye , Li Kheng Chai , Shazia Sadiq , Hongzhi Yin