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Group-based brain connectivity networks have great appeal for researchers interested in gaining further insight into complex brain function and how it changes across different mental states and disease conditions. Accurately constructing…

Applications · Statistics 2013-03-05 Sean L. Simpson , Malaak N. Moussa , Paul J. Laurienti

Learning to sample from complex unnormalized distributions is a fundamental challenge in computational physics and machine learning. While score-based and variational methods have achieved success in continuous domains, extending them to…

Machine Learning · Statistics 2026-03-11 Lei Li , Zhen Wang , Lishuo Zhang

The inception of spatial transcriptomics has allowed improved comprehension of tissue architectures and the disentanglement of complex underlying biological, physiological, and pathological processes through their positional contexts.…

Machine Learning · Computer Science 2023-02-02 Junaid Ahmed , Alhassan S. Yasin

Image-based characterization and disease understanding involve integrative analysis of morphological, spatial, and topological information across biological scales. The development of graph convolutional networks (GCNs) has created the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Kexin Ding , Mu Zhou , Zichen Wang , Qiao Liu , Corey W. Arnold , Shaoting Zhang , Dimitri N. Metaxas

Omics data, such as transcriptomics, proteomics, and metabolomics, provide critical insights into disease mechanisms and clinical outcomes. However, their high dimensionality, small sample sizes, and intricate biological networks pose major…

Machine Learning · Computer Science 2026-01-22 Tiantian Yang , Yuxuan Wang , Zhenwei Zhou , Ching-Ti Liu

Many complex systems involve interactions between more than two agents. Hypergraphs capture these higher-order interactions through hyperedges that may link more than two nodes. We consider the problem of embedding a hypergraph into…

Social and Information Networks · Computer Science 2023-01-06 Xue Gong , Desmond J. Higham , Konstantinos Zygalakis

This paper introduces a generalization of Convolutional Neural Networks (CNNs) to graphs with irregular linkage structures, especially heterogeneous graphs with typed nodes and schemas. We propose a novel spatial convolution operation to…

Machine Learning · Computer Science 2019-07-23 Aravind Sankar , Xinyang Zhang , Kevin Chen-Chuan Chang

Machine learning methods play increasingly important roles in pre-procedural planning for complex surgeries and interventions. Very often, however, researchers find the historical records of emerging surgical techniques, such as the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-06 Jialei Chen , Yujia Xie , Kan Wang , Zih Huei Wang , Geet Lahoti , Chuck Zhang , Mani A Vannan , Ben Wang , Zhen Qian

The interpretation and analysis of the wireless capsule endoscopy recording is a complex task which requires sophisticated computer aided decision (CAD) systems in order to help physicians with the video screening and, finally, with the…

Computer Vision and Pattern Recognition · Computer Science 2016-07-27 Santi Seguí , Michal Drozdzal , Guillem Pascual , Petia Radeva , Carolina Malagelada , Fernando Azpiroz , Jordi Vitrià

This paper presents a novel approach for learned synergistic reconstruction of medical images using multibranch generative models. Leveraging variational autoencoders (VAEs), our model learns from pairs of images simultaneously, enabling…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Noel Jeffrey Pinton , Alexandre Bousse , Catherine Cheze-Le-Rest , Dimitris Visvikis

Many recent generative models make use of neural networks to transform the probability distribution of a simple low-dimensional noise process into the complex distribution of the data. This raises the question of whether biological networks…

Neural and Evolutionary Computing · Computer Science 2018-02-07 Hesham Mostafa , Gert Cauwenberghs

Graph neural networks (GNN) are increasingly used to classify EEG for tasks such as emotion recognition, motor imagery and neurological diseases and disorders. A wide range of methods have been proposed to design GNN-based classifiers.…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Min Wu , Fei He

Presently with technology node scaling, an accurate prediction model at early design stages can significantly reduce the design cycle. Especially during logic synthesis, predicting cell congestion due to improper logic combination can…

Machine Learning · Computer Science 2021-11-12 Amur Ghose , Vincent Zhang , Yingxue Zhang , Dong Li , Wulong Liu , Mark Coates

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

We present a probabilistic framework for modeling structured spatiotemporal dynamics from sparse observations, focusing on cardiac motion. Our approach integrates neural ordinary differential equations (NODEs), graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-09-17 Jaume Banus , Augustin C. Ogier , Roger Hullin , Philippe Meyer , Ruud B. van Heeswijk , Jonas Richiardi

Generative image modeling techniques such as GAN demonstrate highly convincing image generation result. However, user interaction is often necessary to obtain the desired results. Existing attempts add interactivity but require either…

Graphics · Computer Science 2020-09-01 Toby Chong Long Hin , I-Chao Shen , Issei Sato , Takeo Igarashi

We present the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B. subtilis from experimentally obtained, yet mathematically underdetermined microchip array data. By…

Molecular Networks · Quantitative Biology 2009-11-13 C. Christensen , A. Gupta , C. D. Maranas , R. Albert

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

Gastrointestinal endoscopy is a medical procedure that utilizes a flexible tube equipped with a camera and other instruments to examine the digestive tract. This minimally invasive technique allows for diagnosing and managing various…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Pham Vu Hung , Nguyen Duy Manh , Nguyen Thi Oanh , Nguyen Thi Thuy , Dinh Viet Sang

Understanding the dynamics of large-scale brain models remains a central challenge due to the inherent complexity of these systems. In this work, we explore the emergence of complex spatiotemporal patterns in a large scale-brain model…

Neurons and Cognition · Quantitative Biology 2025-12-04 Rosa Maria Delicado , Gemma Huguet , Pau Clusella