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Embedded systems interaction with environment inherently complicates understanding of requirements and their correct implementation. However, product uncertainty is highest during early stages of development. Design verification is an…

Software Engineering · Computer Science 2011-12-20 Hara Gopal Mani Pakala , Dr. Plh Varaprasad , Dr. Raju Kvsvn , Dr. Ibrahim Khan

Space-filling designs are commonly used in computer experiments to fill the space of inputs so that the input-output relationship can be accurately estimated. However, in certain applications such as inverse design or feature-based…

Methodology · Statistics 2023-09-08 Shangkun Wang , Adam P. Generale , Surya R. Kalidindi , V. Roshan Joseph

This PhD thesis covers breakthroughs in several areas of adaptive experiment design: (i) (Chapter 2) Novel clinical trial designs and statistical methods in the era of precision medicine. (ii) (Chapter 3) Multi-armed bandit theory, with…

Methodology · Statistics 2022-05-20 Michael Sklar

Many decision making systems deployed in the real world are not static - a phenomenon known as model adaptation takes place over time. The need for transparency and interpretability of AI-based decision models is widely accepted and thus…

Machine Learning · Computer Science 2021-04-08 André Artelt , Fabian Hinder , Valerie Vaquet , Robert Feldhans , Barbara Hammer

The majority of historical designs are a priori in nature, where a priori indicates a design can be specified in advance of the experiment. The conventional wisdom is that the set of a priori designs is sufficient to produce efficient…

Methodology · Statistics 2022-06-22 Adam Lane

Adaptive experiments are becoming increasingly popular in real-world applications for effectively maximizing in-sample welfare and efficiency by data-driven sampling. Despite their growing prevalence, however, the statistical foundations…

Statistics Theory · Mathematics 2026-04-15 Ziang Niu , Zhimei Ren

Experimental designs are fundamental for estimating causal effects. In some fields, within-subjects designs, which expose participants to both control and treatment at different time periods, are used to address practical and logistical…

Methodology · Statistics 2025-05-08 Justin Ho , Jonathan Min

The increasing availability of passively observed data has yielded a growing methodological interest in "data fusion." These methods involve merging data from observational and experimental sources to draw causal conclusions -- and they…

Methodology · Statistics 2021-12-15 Evan Rosenman , Art B. Owen

We introduce new inference procedures for counterfactual and synthetic control methods for policy evaluation. We recast the causal inference problem as a counterfactual prediction and a structural breaks testing problem. This allows us to…

Econometrics · Economics 2022-01-26 Victor Chernozhukov , Kaspar Wüthrich , Yinchu Zhu

Recommender systems have become an integral part of online platforms, providing personalized recommendations for purchases, content consumption, and interpersonal connections. These systems consist of two sides: the producer side comprises…

Methodology · Statistics 2023-11-08 Yan Wang , Shan Ba

Two-sided platforms are central to modern commerce and content sharing and often utilize A/B testing for developing new features. While user-side experiments are common, seller-side experiments become crucial for specific interventions and…

Methodology · Statistics 2024-02-12 Zhihua Zhu , Zheng Cai , Liang Zheng , Nian Si

Modal testing plays a critical role in structural analysis by providing essential insights into dynamic behaviour across a wide range of engineering industries. In practice, designing an effective modal test campaign involves complex…

Machine Learning · Computer Science 2025-08-21 Collins O. Ogbodo , Timothy J. Rogers , Mattia Dal Borgo , David J. Wagg

We consider after-study statistical inference for sequentially designed experiments wherein multiple units are assigned treatments for multiple time points using treatment policies that adapt over time. Our goal is to provide inference…

Machine Learning · Statistics 2025-06-10 Raaz Dwivedi , Katherine Tian , Sabina Tomkins , Predrag Klasnja , Susan Murphy , Devavrat Shah

A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai

This paper traces the strong relations between experimental design and control, such as the use of optimal inputs to obtain precise parameter estimation in dynamical systems and the introduction of suitably designed perturbations in…

Optimization and Control · Mathematics 2008-03-03 Luc Pronzato

In model checking for regressions, nonparametric estimation-based tests usually have tractable limiting null distributions and are sensitive to oscillating alternative models, but suffer from the curse of dimensionality. In contrast,…

Methodology · Statistics 2019-03-12 Lingzhu Li , Xuehu Zhu , Lixing Zhu

We study counterfactual regression, which aims to map input features to outcomes under hypothetical scenarios that differ from those observed in the data. This is particularly useful for decision-making when adapting to sudden shifts in…

Methodology · Statistics 2025-04-08 Kwangho Kim

With the current trend in Model-Based Systems Engineering towards Digital Engineering and early Validation & Verification, experiments are increasingly used to estimate system parameters and explore design decisions. Managing such…

Software Engineering · Computer Science 2025-09-16 Johan Cederbladh , Loek Cleophas , Eduard Kamburjan , Lucas Lima , Rakshit Mittal , Hans Vangheluwe

Counterfactual explanations are widely used to interpret machine learning predictions by identifying minimal changes to input features that would alter a model's decision. However, most existing counterfactual methods have not been tested…

Machine Learning · Computer Science 2026-02-03 Leonidas Christodoulou , Chang Sun

Randomized experiments, or A/B testing, are the gold standard for evaluating interventions, yet they remain underutilized in inventory management. This study addresses this gap by analyzing A/B testing strategies in multi-item, multi-period…

Methodology · Statistics 2026-02-03 Xinqi Chen , Xingyu Bai , Zeyu Zheng , Nian Si