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Testing for the equality of two high-dimensional distributions is a challenging problem, and this becomes even more challenging when the sample size is small. Over the last few decades, several graph-based two-sample tests have been…

Methodology · Statistics 2019-11-22 Soham Sarkar , Rahul Biswas , Anil K. Ghosh

Machine-learning classifiers can be leveraged as a two-sample statistical test. Suppose each sample is assigned a different label and that a classifier can obtain a better-than-chance result discriminating them. In this case, we can infer…

Machine Learning · Computer Science 2022-12-20 Alejandro Álvarez-Ayllón , Manuel Palomo-Duarte , Juan-Manuel Dodero

A popular approach for testing if two univariate random variables are statistically independent consists of partitioning the sample space into bins, and evaluating a test statistic on the binned data. The partition size matters, and the…

Methodology · Statistics 2016-04-28 Ruth Heller , Yair Heller , Shachar Kaufman , Barak Brill , Malka Gorfine

Two-sample testing is a fundamental problem in statistics. Despite its long history, there has been renewed interest in this problem with the advent of high-dimensional and complex data. Specifically, in the machine learning literature,…

Methodology · Statistics 2019-11-19 Ilmun Kim , Ann B. Lee , Jing Lei

Learning effective data representations has been crucial in non-parametric two-sample testing. Common approaches will first split data into training and test sets and then learn data representations purely on the training set. However,…

Machine Learning · Computer Science 2025-05-09 Xunye Tian , Liuhua Peng , Zhijian Zhou , Mingming Gong , Arthur Gretton , Feng Liu

We develop a new rank-based approach for univariate two-sample testing in the presence of missing data which makes no assumptions about the missingness mechanism. This approach is a theoretical extension of the Wilcoxon-Mann-Whitney test…

Methodology · Statistics 2024-03-25 Yijin Zeng , Niall M. Adams , Dean A. Bodenham

The energy test method is a multi-dimensional test of whether two samples are consistent with arising from the same underlying population, through the calculation of a single test statistic (called the $T$-value). The method has recently…

Data Analysis, Statistics and Probability · Physics 2018-04-19 W. Barter , C. Burr , C. Parkes

The stochastic block model is a popular tool for detecting community structures in network data. Detecting the difference between two community structures is an important issue for stochastic block models. However, the two-sample test has…

Methodology · Statistics 2022-12-21 Kang Fu , Jianwei Hu , Seydou Keita , Hao Liu

So-called linear rank statistics provide a means for distribution-free (even in finite samples), yet highly flexible, two-sample testing in the setting of univariate random variables. Their flexibility derives from a choice of weights that…

Methodology · Statistics 2023-10-03 Dan D. Erdmann-Pham

In this paper, we provide a statistical testing framework to check whether a random sample splitting in a multi-dimensional space is carried out in a valid way, which could be directly applied to A/B testing and multivariate testing to…

Methodology · Statistics 2018-10-11 Jing Miao , Hongyuan Yuan , Zhenyu Yan

Two-sample testing is a fundamental problem in statistics, and many famous two-sample tests are designed to be fully non-parametric. These existing methods perform well with location and scale shifts but are less robust when faced with more…

Methodology · Statistics 2021-10-12 Benjamin Brown , Kai Zhang

We consider the problem of conditional independence testing: given a response Y and covariates (X,Z), we test the null hypothesis that Y is independent of X given Z. The conditional randomization test (CRT) was recently proposed as a way to…

Methodology · Statistics 2021-06-07 Molei Liu , Eugene Katsevich , Lucas Janson , Aaditya Ramdas

We propose a two-sample test for large-dimensional covariance matrices in generalized elliptical models. The test statistic is based on a U-statistic estimator of the squared Frobenius norm of the difference between the two population…

Statistics Theory · Mathematics 2025-07-04 Nina Dörnemann

As predictive algorithms grow in popularity, using the same dataset to both train and test a new model has become routine across research, policy, and industry. Sample-splitting attains valid inference on model properties by using separate…

Econometrics · Economics 2025-11-27 Bruno Fava

Deep neural two-sample tests have recently shown strong power for detecting distributional differences between groups, yet their black-box nature limits interpretability and practical adoption in biomedical analysis. Moreover, most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Masoumeh Javanbakhat , Piotr Komorowski , Dilyara Bareeva , Wei-Chang Lai , Wojciech Samek , Christoph Lippert

In the context of supervised parametric models, we introduce the concept of e-values. An e-value is a scalar quantity that represents the proximity of the sampling distribution of parameter estimates in a model trained on a subset of…

Machine Learning · Statistics 2022-07-19 Subhabrata Majumdar , Snigdhansu Chatterjee

We develop E-variables for testing whether two or more data streams come from the same source or not, and more generally, whether the difference between the sources is larger than some minimal effect size. These E-variables lead to exact,…

Methodology · Statistics 2022-06-23 Rosanne Turner , Alexander Ly , Peter Grünwald

The so-called 'energy test' is a frequentist technique used in experimental particle physics to decide whether two samples are drawn from the same distribution. Its usage requires a good understanding of the distribution of the test…

Data Analysis, Statistics and Probability · Physics 2019-03-12 Thomas P. S. Gillam , Christopher G. Lester

Intelligent test requires efficient and effective analysis of high-dimensional data in a large scale. Traditionally, the analysis is often conducted by human experts, but it is not scalable in the era of big data. To tackle this challenge,…

Machine Learning · Computer Science 2022-07-04 Yiwen Liao , Tianjie Ge , Raphaël Latty , Bin Yang

The two-sample problem, which consists in testing whether independent samples on $\mathbb{R}^d$ are drawn from the same (unknown) distribution, finds applications in many areas. Its study in high-dimension is the subject of much attention,…

Statistics Theory · Mathematics 2023-02-09 Stephan Clémençon , Myrto Limnios , Nicolas Vayatis