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Convolutional Neural Networks have shown promising effectiveness in identifying different types of cancer from radiographs. However, the opaque nature of CNNs makes it difficult to fully understand the way they operate, limiting their…

TCAV (Testing with Concept Activation Vectors) is an interpretability method that assesses the alignment between the internal representations of a trained neural network and human-understandable, high-level concepts. Though effective, TCAV…

This article presents the design, experiments and results of our solution submitted to the 2018 ISIC challenge: Skin Lesion Analysis Towards Melanoma Detection. We design a pipeline using state-of-the-art Convolutional Neural Network (CNN)…

Many biological processes are governed by protein-ligand interactions. One such example is the recognition of self and nonself cells by the immune system. This immune response process is regulated by the major histocompatibility complex…

The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH in cancer is represented by clonal evolution where different sub-clones compete with each other for resources under conditions of Darwinian natural…

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

Convolutional Neural Networks have demonstrated human-level performance in the classification of melanoma and other skin lesions, but evident performance disparities between differing skin tones should be addressed before widespread…

Melanoma skin cancer is one of the most dangerous and life-threatening cancer. Exposure to ultraviolet rays may damage the skin cell's DNA, which causes melanoma skin cancer. However, it is difficult to detect and classify melanoma and…

Our goal is to bridge human and machine intelligence in melanoma detection. We develop a classification system exploiting a combination of visual pre-processing, deep learning, and ensembling for providing explanations to experts and to…

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a…

Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…

Anticancer peptides (ACPs) are a class of molecules that have gained significant attention in the field of cancer research and therapy. ACPs are short chains of amino acids, the building blocks of proteins, and they possess the ability to…

Cancer is a primary cause of human death, but discovering drugs and tailoring cancer therapies are expensive and time-consuming. We seek to facilitate the discovery of new drugs and treatment strategies for cancer using variational…

Human leukocyte antigen (HLA) is an important molecule family in the field of human immunity, which recognizes foreign threats and triggers immune responses by presenting peptides to T cells. In recent years, the synthesis of tumor vaccines…

Many existing models for clinical trial outcome prediction are optimized using task-specific loss functions on trial phase-specific data. While this scheme may boost prediction for common diseases and drugs, it can hinder learning of…

In this paper, we studied extensively on different deep learning based methods to detect melanoma and skin lesion cancers. Melanoma, a form of malignant skin cancer is very threatening to health. Proper diagnosis of melanoma at an earlier…

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in…