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The transport and manipulation of particles and cells in microfluidic devices has become a core methodology in domains ranging from molecular biology to manufacturing and drug design. The rational design and operation of such devices can…

Computational Engineering, Finance, and Science · Computer Science 2020-07-15 Dmitry Alexeev , Lucas Amoudruz , Sergey Litvinov , Petros Koumoutsakos

Human action-reaction synthesis, a fundamental challenge in modeling causal human interactions, plays a critical role in applications ranging from virtual reality to social robotics. While diffusion-based models have demonstrated promising…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Wentao Jiang , Jingya Wang , Kaiyang Ji , Baoxiong Jia , Siyuan Huang , Ye Shi

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

The multiscale gap-tooth scheme uses a given microscale simulator of complicated physical processes to enable macroscale simulations by computing only only small sparse patches. This article develops the gap-tooth scheme to the case of…

Dynamical Systems · Mathematics 2014-05-29 Meng Cao , A. J. Roberts

Numerous mixing strategies in microfluidic devices rely on chaotic advection by time-dependent body forces. The question of determining the required forcing function to achieve optimal mixing at a given kinetic energy or power input remains…

Fluid Dynamics · Physics 2011-10-18 Qizheng Yan , David Saintillan

In conventional fluid mechanics, the chemical composition and thermodynamic state of a fluid-solid interface are not considered when establishing velocity-field boundary conditions. As a consequence, fluid simulations are usually not able…

We have developed and characterized two novel micro flow sensors based on measuring the electrical impedance of the interface between the flowing liquid and metallic electrodes embedded on the channel walls. These flow sensors are very…

Fluid Dynamics · Physics 2012-07-17 Nima Arjmandi , Chengxun Liu , Willem Van Roy , Liesbet Lagae , Gustaaf Borghs

Numerical simulations of surface acoustic wave (SAW)-induced acoustic streaming are highly sensitive to the choice of second-order boundary conditions. This study systematically compares the no-slip (NS) and Stokes slip (SD) boundary…

Fluid Dynamics · Physics 2025-11-18 Qinran Wei , Suyu Ding , Yang Zhao , Yuanpeng Ma , Dachuan Sang , Dong Zhang , Xiasheng Guo

The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding assays, a fully biocompatible in vitro model was…

Acoustic traps are used to capture and handle suspended microparticles and cells in microfluidic applications. A particular simple and much-used acoustic trap consists of a commercially available, millimeter-sized, liquid-filled glass…

Fluid Dynamics · Physics 2017-08-30 Mikkel W. H. Ley , Henrik Bruus

Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…

Fluid Dynamics · Physics 2010-10-19 Cheng Wang , Shreyas Jalikop , Sascha Hilgenfeldt

Mixing of reagents in microfluidics is necessary for various applications however, due to the laminar nature of flows, efficient mixing in a small span of length and time becomes difficult. The analysis of mixing of non-Newtonian fluids is…

Fluid Dynamics · Physics 2022-09-01 Anirban Roy , Avinash Kumar , Chirodeep Bakli , Gargi Das

Mixing in fluids is a rapidly developing field of fluid mechanics \cite{Sreen,Shr,War}, being an important industrial and environmental problem. The mixing of liquids at low Reynolds numbers is usually quite weak in simple flows, and it…

Chaotic Dynamics · Physics 2009-11-07 Alexander Groisman , Victor Steinberg

A new class of multiscale scheme is presented for micro-hydrodynamic problems based on a dual representation of the fluid observables. The hybrid model is first tested against the classical flow between two parallel plates and then applied…

Computational Physics · Physics 2020-06-29 Andrea Montessori , Adriano Tiribocchi , Marco Lauricella , Fabio Bonaccorso , Sauro Succi

Performing geometry-resolved simulations of flows over rough and porous walls is highly expensive due to their multiscale characteristics. Effective models that circumvent this difficulty are often used to investigate the interaction…

Fluid Dynamics · Physics 2023-09-22 Vedanth N Kuchibhotla , Sujit Kumar Sahoo , Y. Sudhakar

We derive analytical expressions for the three-dimensional (3D) acoustophoretic motion of spherical microparticles in rectangular microchannels. The motion is generated by the acoustic radiation force and the acoustic streaming-induced drag…

The flow of amorphous solids results from a combination of elastic deformation and local structural rearrangements, which induce non-local elastic deformations. These elements are incorporated into a mechanically-consistent mesoscopic model…

Soft Condensed Matter · Physics 2015-06-12 Alexandre Nicolas , Jean-Louis Barrat

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

Fluid Dynamics · Physics 2025-08-04 Maxx Yung

Acoustic streaming can be generated around sharp structures, even when the acoustic wavelength is much larger than the vessel size. This sharp-edge streaming can be relatively intense, \textcolor{blue}{owing to the strongly focused inertial…

Fluid Dynamics · Physics 2020-06-22 Chuanyu Zhang , Xiaofeng Guo , Laurent Royon , Philippe Brunet

Active- and transfer-learning are applied to polymer flows for the multiscale discovery of effective constitutive approximations required in viscoelastic flow simulation. The result is macroscopic rheology directly connected to a…

Computational Physics · Physics 2021-02-03 Lifei Zhao , Zhen Li , Zhicheng Wang , Bruce Caswell , Jie Ouyang , George Em Karniadakis