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Early detection of disease outbreaks is crucial to ensure timely intervention by the health authorities. Due to the challenges associated with traditional indicator-based surveillance, monitoring informal sources such as online media has…

We develop Process Execution Graphs (PEG), a document-level representation of real-world wet lab biochemistry protocols, addressing challenges such as cross-sentence relations, long-range coreference, grounding, and implicit arguments. We…

Computation and Language · Computer Science 2021-04-15 Ronen Tamari , Fan Bai , Alan Ritter , Gabriel Stanovsky

ClinicalTrials .gov (CT .gov) is the largest publicly accessible registry of clinical studies, yet its registry-oriented architecture and heterogeneous adverse event (AE) terminology limit systematic pharmacovigilance (PV) analytics. AEs…

Computation and Language · Computer Science 2026-03-19 Jeffery L. Painter , François Haguinet , Andrew Bate

Phase I dose-escalation trials constitute the first step in investigating the safety of potentially promising drugs in humans. Conventional methods for phase I dose-escalation trials are based on a single treatment schedule only. More…

Applications · Statistics 2021-03-04 Burak Kürsad Günhan , Sebastian Weber , Abdelkader Seroutou , Tim Friede

Extracting meaningful drug-related information chunks, such as adverse drug events (ADE), is crucial for preventing morbidity and saving many lives. Most ADEs are reported via an unstructured conversation with the medical context, so…

Computation and Language · Computer Science 2023-08-16 Jie Yang , Soyeon Caren Han , Siqu Long , Josiah Poon , Goran Nenadic

Open data sets that contain personal information are susceptible to adversarial attacks even when anonymized. By performing low-cost joins on multiple datasets with shared attributes, malicious users of open data portals might get access to…

Cryptography and Security · Computer Science 2022-11-30 Kaustav Bhattacharjee , Akm Islam , Jaideep Vaidya , Aritra Dasgupta

Physics Engines (PEs) are fundamental software frameworks that simulate physical interactions in applications ranging from entertainment to safety-critical systems. Despite their importance, PEs suffer from physics failures, deviations from…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shuqing Li , Qiang Chen , Xiaoxue Ren , Michael R. Lyu

We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's…

Computation and Language · Computer Science 2022-11-17 Aakanksha Naik , Sravanthi Parasa , Sergey Feldman , Lucy Lu Wang , Tom Hope

In the virtual realm, individuals with photosensitive epilepsy (PSE) encounter challenges when using devices, resulting in exposure to unpredictable seizure-causing visual stimuli. The current norm for preventing epileptic flashes in media…

Computers and Society · Computer Science 2025-07-29 Ishan Pendyala

Drug Side-Effects (DSEs) have a high impact on public health, care system costs, and drug discovery processes. Predicting the probability of side-effects, before their occurrence, is fundamental to reduce this impact, in particular on drug…

Quantitative Methods · Quantitative Biology 2022-02-17 Pietro Bongini , Franco Scarselli , Monica Bianchini , Giovanna Maria Dimitri , Niccolò Pancino , Pietro Liò

Inter-personal relationship is the basis of human society. In order to automatically identify the relations between persons from texts, we need annotated data for training systems. However, there is a lack of a massive amount of such data…

Computation and Language · Computer Science 2019-08-13 Haitao Wang , Zhengqiu He , Jin Ma , Wenliang Chen , Min Zhang

Clinicians prescribe antibiotics by looking at the patient's health record with an experienced eye. However, the therapy might be rendered futile if the patient has drug resistance. Determining drug resistance requires time-consuming…

Artificial Intelligence · Computer Science 2023-03-09 Honglin Shu , Pei Gao , Lingwei Zhu , Zheng Chen

User-generated data sources have gained significance in uncovering Adverse Drug Reactions (ADRs), with an increasing number of discussions occurring in the digital world. However, the existing clinical corpora predominantly revolve around…

Pharmaco-epidemiology (PE) is the study of uses and effects of drugs in well defined populations. As medico-administrative databases cover a large part of the population, they have become very interesting to carry PE studies. Such databases…

Artificial Intelligence · Computer Science 2017-09-12 Yann Dauxais , Thomas Guyet , David Gross-Amblard , André Happe

The Emotion Cause Extraction (ECE)} task aims to identify clauses which contain emotion-evoking information for a particular emotion expressed in text. We observe that a widely-used ECE dataset exhibits a bias that the majority of annotated…

Computation and Language · Computer Science 2023-12-20 Hanqi Yan , Lin Gui , Gabriele Pergola , Yulan He

1. A hard stop for the implementation of rigorous conservation initiatives is our lack of key species data, especially occurrence data. Furthermore, researchers have to contend with an accelerated speed at which new information must be…

Machine Learning · Computer Science 2025-11-07 Vasco V. Branco , Jandó Benedek , Lidia Pivovarova , Luís Correia , Pedro Cardoso

Anomaly detection is a common analytical task that aims to identify rare cases that differ from the typical cases that make up the majority of a dataset. When applied to the analysis of event sequence data, the task of anomaly detection can…

Human-Computer Interaction · Computer Science 2020-04-16 Shunan Guo , Zhuochen Jin , Qing Chen , David Gotz , Hongyuan Zha , Nan Cao

Physicians learn primarily about illicit drugs from clinical overdose cases, limiting their understanding of real-world usage. Meanwhile, drug users share first-hand experiences online, offering insights into dosage and effects of drugs. To…

Computation and Language · Computer Science 2026-05-27 Zewei Wang , Zihan Xu , Yishu Wei , Michael Chary , Yifan Peng

There are a few challenges related to the task of biomedical named entity recognition, which are: the existing methods consider a fewer number of biomedical entities (e.g., disease, symptom, proteins, genes); and these methods do not…

Computation and Language · Computer Science 2022-07-05 Shaina Raza , Brian Schwartz

In the research and development (R&D) and verification and validation (V&V) phases of autonomous driving decision-making and planning systems, it is necessary to integrate human factors to achieve decision-making and evaluation that align…

Human-Computer Interaction · Computer Science 2026-03-18 Xinzheng Wu , Junyi Chen , Peiyi Wang , Shunxiang Chen , Haolan Meng , Yong Shen