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Cells of the human body have nearly identical genome but exhibit very different phenotypes that allow them to carry out specific functions and react to changes in their surrounding environment. This division of labour is achieved by…

Cell Behavior · Quantitative Biology 2021-11-24 Hanan Dreiwi , Flavia Feliciangeli , Mario Castro , Grant Lythe , Carmen Molina-París , Martín López-García

Confluent cell monolayers and epithelia tissues show remarkable patterns and correlations in structural arrangements and actively-driven collective flows. We simulate these properties using multiphase field models. The models are based on…

Soft Condensed Matter · Physics 2021-12-08 Dennis Wenzel , Axel Voigt

For proliferating cells subject to both division and death, how can one estimate the average generation number of the living population without continuous observation or a division-diluting dye? In this paper we provide a method for cell…

Quantitative Methods · Quantitative Biology 2017-04-28 Tom S. Weber , Leila Perie , Ken R. Duffy

Creating the best possible conditions is essential for proper cell growth. Incubators, a type of biotechnological instrument, are used to simulate this condition and maintain the cells within them. The processes involved in creating a…

Systems and Control · Electrical Eng. & Systems 2022-08-23 Fehmi Can Ay , Nesim Bilici , Rahmetullah Varol , Atasangu Yilmaz , Ufuk Gorkem Kirabali , Abdurrahim Yilmaz , Huseyin Uvet

In vitro velocities of several cell types have been measured using computer controlled video microscopy, which allowed to record the cells' trajectories over several days. On the basis of our large data sets we show that the locomotion…

Biological Physics · Physics 2009-10-31 A. Czirok , K. Schlett , E. Madarasz , T. Vicsek

Motility is an essential factor for an organism's survival and diversification. With the advent of novel single-cell technologies, analytical frameworks and theoretical methods, we can begin to probe the complex lives of microscopic motile…

Femtocells are recognized effective for improving network coverage and capacity, and reducing power consumption due to the reduced range of wireless transmissions. Although highly appealing, a plethora of challenging problems need to be…

Networking and Internet Architecture · Computer Science 2013-12-10 Hui Zhou , Donglin Hu , Saketh Anuma Reddy , Shiwen Mao , Prathima Agrawal

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

Multiobject tracking provides situational awareness that enables new applications for modern convenience, applied ocean sciences, public safety, and homeland security. In many multiobject tracking applications, including radar and sonar…

Signal Processing · Electrical Eng. & Systems 2025-04-24 Thomas Kropfreiter , Jason L. Williams , Florian Meyer

Cell microscopy data are abundant; however, corresponding segmentation annotations remain scarce. Moreover, variations in cell types, imaging devices, and staining techniques introduce significant domain gaps between datasets. As a result,…

Machine Learning · Computer Science 2026-01-27 Rüveyda Yilmaz , Zhu Chen , Yuli Wu , Johannes Stegmaier

Accurate cell counting in microscopic images is important for medical diagnoses and biological studies. However, manual cell counting is very time-consuming, tedious, and prone to subjective errors. We propose a new density regression-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Hua Li , Mark Anastasio

While analyzing mobile systems we often approximate the actual coverage surface and assume an ideal cell shape. In a multi-cellular network, because of its tessellating nature, a hexagon is more preferred than a circular geometry. Despite…

Information Theory · Computer Science 2013-06-04 Mouhamed Abdulla , Yousef R. Shayan

The development of traction-force microscopy, in the past two decades, has created the unprecedented opportunity of performing direct mechanical measurements on living cells as they adhere or crawl on uniform or micro-patterned substrates.…

Biological Physics · Physics 2019-10-25 Luca Giomi

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Activity detection is an important task in the next generation grant-free multiple access. While there are a number of existing algorithms designed for this purpose, they mostly require precise information about the network, such as…

Machine Learning · Computer Science 2024-02-05 Hao Zhang , Qingfeng Lin , Yang Li , Lei Cheng , Yik-Chung Wu

The ability of a cell to communicate with its environment is essential for key cellular functions like replication, metabolism, or cell fate decisions. The involved molecular mechanisms are highly dynamic and difficult to capture…

Human-Computer Interaction · Computer Science 2025-09-11 Lena Cibulski , Fiete Haack , Adelinde Uhrmacher , Stefan Bruckner

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Chong Zhang , Shaofei Wang , Miguel A. Gonzalez-Ballester , Julian Yarkony

Cell detection and segmentation are integral parts of automated systems in digital pathology. Encoder-decoder networks have emerged as a promising solution for these tasks. However, training of these networks has typically required full…

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest