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Related papers: Multibody molecular docking on a quantum annealer

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The Coupled Cluster (CC) method is used to compute the electronic correlation energy in atoms and molecules and often leads to highly accurate results. However, due to its single-reference nature, standard CC in its projected form fails to…

Quantum annealing (QA) is a method for solving combinatorial optimization problems. We can estimate the computational time for QA using the adiabatic condition. The adiabatic condition consists of two parts: an energy gap and a transition…

Quantum Physics · Physics 2024-08-28 Hiroshi Hayasaka , Takashi Imoto , Yuichiro Matsuzaki , Shiro Kawabata

We propose a new kernel that quantifies success for the task of computing a core-periphery partition for an undirected network. Finding the associated optimal partitioning may be expressed in the form of a quadratic unconstrained binary…

Social and Information Networks · Computer Science 2022-01-06 Catherine F. Higham , Desmond J. Higham , Francesco Tudisco

Quantum tunneling, a phenomenon in which a quantum state traverses energy barriers above the energy of the state itself, has been hypothesized as an advantageous physical resource for optimization. Here we show that multiqubit tunneling…

Quantum computing and quantum Monte Carlo (QMC) are respectively the state-of-the-art quantum and classical computing methods for understanding many-body quantum systems. Here, we propose a hybrid quantum-classical algorithm that integrates…

Quantum Physics · Physics 2025-11-17 Yukun Zhang , Yifei Huang , Jinzhao Sun , Dingshun Lv , Xiao Yuan

Quantum optimization is the most mature quantum computing technology to date, providing a promising approach towards efficiently solving complex combinatorial problems. Methods such as adiabatic quantum computing (AQC) have been employed in…

Lattice models have been used extensively over the past thirty years to examine the principles of protein folding and design. These models can be used to determine the conformation of the lowest energy fold out of a large number of possible…

Quantum Physics · Physics 2018-11-05 Tomáš Babej , Christopher Ing , Mark Fingerhuth

Collaborative filtering models generally perform better than content-based filtering models and do not require careful feature engineering. However, in the cold-start scenario collaborative information may be scarce or even unavailable,…

Information Retrieval · Computer Science 2022-05-13 Artyom Nikitin , Andrei Chertkov , Rafael Ballester-Ripoll , Ivan Oseledets , Evgeny Frolov

Entanglement is crucial to many quantum applications including quantum information processing, simulation of quantum many-body systems, and quantum-enhanced sensing. Molecules, because of their rich internal structure and interactions, have…

Quantum Gases · Physics 2024-06-18 Connor M. Holland , Yukai Lu , Lawrence W. Cheuk

Optimisation algorithms designed to work on quantum computers or other specialised hardware have been of research interest in recent years. Many of these solver can only optimise problems that are in binary and quadratic form. Quadratic…

Optimization and Control · Mathematics 2022-06-23 Mayowa Ayodele

We propose a practical, physics-inspired benchmarking suite to challenge both quantum and classical computers by mapping real-time quantum dynamics to a common optimization format. Using a parallel-in-time encoding, we convert the real-time…

Quantum Physics · Physics 2026-04-23 Philipp Hanussek , Jakub Pawłowski , Zakaria Mzaouali , Bartłomiej Gardas

Molecular docking, given a ligand molecule and a ligand binding site (called ``pocket'') on a protein, predicting the binding mode of the protein-ligand complex, is a widely used technique in drug design. Many deep learning models have been…

Biomolecules · Quantitative Biology 2023-02-24 Yuejiang Yu , Shuqi Lu , Zhifeng Gao , Hang Zheng , Guolin Ke

Quantum computing is poised to transform the financial industry, yet its advantages over traditional methods have not been evidenced. As this technology rapidly evolves, benchmarking is essential to fairly evaluate and compare different…

Optimization and Control · Mathematics 2025-02-11 Ying Chen , Thorsten Koch , Hanqiu Peng , Hongrui Zhang

Quantum technology is maturing to the point where quantum devices, such as quantum communication systems, quantum random number generators and quantum simulators, may be built with capabilities exceeding classical computers. A quantum…

Adiabatic quantum optimization has been proposed as a route to solve NP-complete problems, with a possible quantum speedup compared to classical algorithms. However, the precise role of quantum effects, such as entanglement, in these…

Quantum Gases · Physics 2015-06-23 Philipp Hauke , Lars Bonnes , Markus Heyl , Wolfgang Lechner

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

With the development of quantum computing, the use of quantum algorithms to solve combinatorial optimization problems on quantum computers has become a major research focus. The Quadratic Unconstrained Binary Optimization (QUBO) model…

Computational Engineering, Finance, and Science · Computer Science 2025-04-10 Haoqian Pan , Changhong Lu

We present a method to calculate many-body states of interacting carriers in million atom quantum nanostructures based on atomistic tight-binding calculations and a combination of iterative selection of configurations and perturbation…

Mesoscale and Nanoscale Physics · Physics 2020-05-27 Moritz Cygorek , Matthew Otten , Marek Korkusinski , Pawel Hawrylak

With the aim of establishing a framework to efficiently perform the practical application of quantum chemistry simulation on near-term quantum devices, we envision a hybrid quantum--classical framework for leveraging problem decomposition…

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan
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