Related papers: Local sensing of absolute refractive index during …
We demonstrate thin, flexible, metamaterial films with a strong, narrowband, polarization- and angle-insensitive absorption designed for wavelengths near one millimeter. These structures, fabricated by photolithography on a commercially…
The five-layer nanorod-mediated surface plasmon sensor with inhomogeneous liquid crystal layer was theoretically investigated. The reflectance as the function of the incident angle was calculated at different voltages applied to the liquid…
Many bacterial species readily develop biofilms that act as a protective matrix against external challenge, e.g. from antimicrobial treatment. Therefore, biofilms are often responsible for persistent and recurring infections. Established…
High-precision laser interferometric instruments require optical surfaces with a close to perfect contour, as well as low scattering and absorption. Especially point absorbers are problematic because they heat up at high optical intensities…
In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To…
Absorption spectroscopy is widely used in sensing and astronomy to understand molecular compositions on microscopic to cosmological scales. However, typical dispersive spectroscopic techniques require multichannel detection, fundamentally…
The short and intense pulses of the new X-ray free electron lasers, now operational or under construction, may make possible diffraction experiments on single molecule-sized objects with high resolution, before radiation damage destroys the…
Based on the basic theory of the microfiber loop resonator, we exploit the application of microfiber loop resonators in biochemical sensing. We set up a reliable theoretical model and optimize the structural parameters of microfiber loop…
Decentralized diagnostic testing that is accurate, portable, quantitative, and capable of making multiple simultaneous measurements of different biomarkers at the point-of-need remains an important unmet need in the post-pandemic world.…
Several techniques have been employed for the direct visualization of cytoskeletal filaments and their associated proteins. Total-internal-reflection-fluorescence (TIRF) microscopy has a high signal-to-background ratio, but it suffers from…
The success of therapeutic antibodies relies on their ability to selectively bind antigens. AI-based antibody design protocols have shown promise in generating epitope-specific designs. Many of these protocols use an inverse folding step to…
Sequence coverage in MS analysis of protein digestion-derived peptides is a key issue for detailed characterization of proteins or identification at low quantities. In gel-based proteomics studies, the sequence coverage greatly depends on…
Refraction of an optical probe beam by a plasma can be measured with angular filter refractometry (AFR), which produces an image containing intensity contours that correspond to curves of constant refraction angle. Further analysis is…
A method to engineer the refractive indices of functional materials (TiO2, ZnO, SnO2, SiO2), by nanostructuring in the deep sub-wavelength regime (<20nm), is presented. Block-copolymer templating combined with a wet processing route is used…
Methods to visualize the two-dimensional distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high…
Theoretical model of the enhanced optical resolution of the surface plasmon immersion microscope is developed, which is based on the optics of surface plasmon Bloch waves in the tightly bound approximation. It is shown that a similar…
We describe a high resolution imaging detector based on a single 80 mm micro-channel-plate (MCP) and a phosphor screen mounted on a UHV flange of only 100 mm inner diameter. It relies on standard components and we describe its performance…
Detecting specific target analytes and differentiating them from interfering background effects is a crucial but challenging task in complex multi-component solutions commonly encountered in environmental, chemical, biological, and medical…
We present a full-spectrum machine learning framework for refractive index sensing using simulated absorption spectra from meta-grating structures composed of titanium or silicon nanorods under TE and TM polarizations. Linear regression was…
Determination of refractive index of micro-disks of a calcinated ($1100^\circ$C in air) photo-resist SZ2080$^\mathrm{TM}$ was carried out using transmission and reflection spectroscopy. Interference fringes at specific…