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Three statistical studies, all published between 2004 and 2008 but without referring to one another, assert a useful equivalence involving the hazard ratio, a parameter estimated for time to event data by the frequently used proportional…

Methodology · Statistics 2021-09-28 David M. Thompson , Julia E. Reid

The standard odds ratio of logistic regression is foundational but limited to individual explanatory variables. This work derives a multivariable odds ratio that applies to all the explanatory variables in all their combinations.

Methodology · Statistics 2025-04-25 José Raúl Martínez

The risk ratio is a popular tool for summarizing the relationship between a binary covariate and outcome, even when outcomes may be dependent. Investigations of infectious disease outcomes in cohort studies of individuals embedded within…

Methodology · Statistics 2017-07-20 Olga Morozova , Ted Cohen , Forrest W. Crawford

Balancing a rare and serious possibility against a more common and less serious one is a familiar problem in many situations, such as the prediction of rare diseases. The relative costs of forecasting errors can be used for any prediction…

Methodology · Statistics 2009-05-04 Paul T Seed

The hazard ratio, typically estimated using Cox's famous proportional hazards model, is the most common effect measure used to describe the association or effect of a covariate on a time-to-event outcome. In recent years the hazard ratio…

Methodology · Statistics 2026-01-15 Jonathan W. Bartlett , Dominic Magirr , Tim P. Morris

In the last decades, it has been discussed the use of epidemiological prevalence ratio (PR) rather than odds ratio as a measure of association to be estimated in cross-sectional studies. The main difficulties in use of statistical models…

Sequential estimators are proposed for the relative risk, odds ratio, log relative risk or log odds ratio of a dichotomous attribute in two populations. The estimators take the same number of observations from each population, and guarantee…

Methodology · Statistics 2026-04-07 Luis Mendo

The attributable risk, often called the population attributable risk, is in many epidemiological contexts a more relevant measure of exposure-disease association than the excess risk, relative risk, or odds ratio. When estimating…

Statistics Theory · Mathematics 2008-12-31 Daniel B. Rubin

Hazard ratios are often used to evaluate time to event outcomes, but they may be hard to interpret. A particular issue arise because hazards are typically estimated conditional on survival, i.e.\ on left truncated samples. Then, hazard…

Methodology · Statistics 2018-03-23 Mats Julius Stensrud

In epidemiological research, it is common to investigate the interaction between risk factors for an outcome such as a disease and hence to estimate the risk associated with being exposed for either or both of two risk factors under…

Methodology · Statistics 2020-08-05 Jesse Huang , Ingrid Kockum , Pernilla Stridh

The robust Poisson method is becoming increasingly popular when estimating the association of exposures with a binary outcome. Unlike the logistic regression model, the robust Poisson method yields results that can be interpreted as risk or…

Methodology · Statistics 2022-09-14 Denis Talbot , Miceline Mésidor , Yohann Chiu , Marc Simard , Caroline Sirois

We compare the risk of ridge regression to a simple variant of ordinary least squares, in which one simply projects the data onto a finite dimensional subspace (as specified by a Principal Component Analysis) and then performs an ordinary…

Machine Learning · Statistics 2013-06-03 Paramveer S. Dhillon , Dean P. Foster , Sham M. Kakade , Lyle H. Ungar

The odds ratio measure is used in health and social surveys where the odds of a certain event is to be compared between two populations. It is defined using logistic regression, and requires that data from surveys are accompanied by their…

Methodology · Statistics 2014-07-01 C. Goga , A Ruiz-Gazen

In clinical prediction modeling, model updating refers to the practice of modifying a prediction model before it is used in a new setting. In the context of logistic regression for a binary outcome, one of the simplest updating methods is a…

Applications · Statistics 2022-04-12 Mohsen Sadatsafavi , Hamid Tavakoli , Abdollah Safari

The hazard ratio is one of the most commonly reported measures of treatment effect in randomised trials, yet the source of much misinterpretation. This point was made clear by (Hernan, 2010) in commentary, which emphasised that the hazard…

Statistics Theory · Mathematics 2018-10-23 Torben Martinussen , Stijn Vansteelandt , Per Kragh Andersen

Regression is one of the most fundamental statistical inference problems. A broad definition of regression problems is as estimation of the distribution of an outcome using a family of probability models indexed by covariates. Despite the…

Statistics Theory · Mathematics 2023-09-26 Peter Mueller , Fernando Andrés Quintana , Garritt L. Page

Logistic regression is an important statistical tool for assessing the probability of an outcome based upon some predictive variables. Standard methods can only deal with precisely known data, however many datasets have uncertainties which…

Methodology · Statistics 2022-06-09 Nicholas Gray , Scott Ferson

Given two populations from which independent binary observations are taken with parameters $p_1$ and $p_2$ respectively, estimators are proposed for the relative risk $p_1/p_2$, the odds ratio $p_1(1-p_2)/(p_2(1-p_1))$ and their logarithms.…

Methodology · Statistics 2026-04-06 Luis Mendo

Background: A wide range of diseases show some degree of clustering in families; family history is therefore an important aspect for clinicians when making risk predictions. Familial aggregation is often quantified in terms of a familial…

Applications · Statistics 2018-01-31 Morten Valberg , Mats Julius Stensrud , Odd O. Aalen

Risk scores are simple classification models that let users make quick risk predictions by adding and subtracting a few small numbers. These models are widely used in medicine and criminal justice, but are difficult to learn from data…

Machine Learning · Statistics 2020-10-21 Berk Ustun , Cynthia Rudin
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