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Weakly supervised whole slide image classification is usually formulated as a multiple instance learning (MIL) problem, where each slide is treated as a bag, and the patches cut out of it are treated as instances. Existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Linhao Qu , Yingfan Ma , Xiaoyuan Luo , Manning Wang , Zhijian Song

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

Multi-instance learning (MIL) deals with objects represented as bags of instances and can predict instance labels from bag-level supervision. However, significant performance gaps exist between instance-level MIL algorithms and supervised…

Machine Learning · Computer Science 2022-10-06 Weijia Zhang , Xuanhui Zhang , Han-Wen Deng , Min-Ling Zhang

Contrastive learning is a well-established paradigm in representation learning. The standard framework of contrastive learning minimizes the distance between "similar" instances and maximizes the distance between dissimilar ones in the…

Machine Learning · Computer Science 2025-02-06 Naghmeh Ghanooni , Barbod Pajoum , Harshit Rawal , Sophie Fellenz , Vo Nguyen Le Duy , Marius Kloft

Multiple instance learning (MIL) problem is currently solved from either bag-classification or instance-classification perspective, both of which ignore important information contained in some instances and result in limited performance.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Yingfan Ma , Xiaoyuan Luo , Mingzhi Yuan , Xinrong Chen , Manning Wang

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

Contrastive Learning (CL) has been proved to be a powerful self-supervised approach for a wide range of domains, including computer vision and graph representation learning. However, the incremental learning issue of CL has rarely been…

Machine Learning · Computer Science 2023-01-31 Cheng Ji , Jianxin Li , Hao Peng , Jia Wu , Xingcheng Fu , Qingyun Sun , Phillip S. Yu

Supervised contrastive learning (SCL) frameworks treat each class as independent and thus consider all classes to be equally important. This neglects the common scenario in which label hierarchy exists, where fine-grained classes under the…

Machine Learning · Computer Science 2024-02-02 Ruixue Lian , William A. Sethares , Junjie Hu

Multiple instance learning (MIL) is concerned with learning from sets (bags) of objects (instances), where the individual instance labels are ambiguous. In this setting, supervised learning cannot be applied directly. Often, specialized MIL…

Machine Learning · Statistics 2014-12-04 Veronika Cheplygina , David M. J. Tax , Marco Loog

Self-supervised learning (SSL) methods targeting scene images have seen a rapid growth recently, and they mostly rely on either a dedicated dense matching mechanism or a costly unsupervised object discovery module. This paper shows that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Ke Zhu , Minghao Fu , Jianxin Wu

Semi-supervised medical image segmentation has attracted much attention in recent years because of the high cost of medical image annotations. In this paper, we propose a novel Inherent Consistent Learning (ICL) method, aims to learn robust…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ye Zhu , Jie Yang , Si-Qi Liu , Ruimao Zhang

Recent pseudo-bag augmentation methods for Multiple Instance Learning (MIL)-based Whole Slide Image (WSI) classification sample instances from a limited number of bags, resulting in constrained diversity. To address this issue, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Bo Zhang , Xu Xinan , Shuo Yan , Yu Bai , Zheng Zhang , Wufan Wang , Wendong Wang

Weakly supervised multiple instance learning (MIL) is a challenging task given that only bag-level labels are provided, while each bag typically contains multiple instances. This topic has been extensively studied in histopathological image…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Bodong Zhang , Hamid Manoochehri , Xiwen Li , Beatrice S. Knudsen , Tolga Tasdizen

This work aims at improving instance retrieval with self-supervision. We find that fine-tuning using the recently developed self-supervised (SSL) learning methods, such as SimCLR and MoCo, fails to improve the performance of instance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Zelu Deng , Yujie Zhong , Sheng Guo , Weilin Huang

Recently, as an effective way of learning latent representations, contrastive learning has been increasingly popular and successful in various domains. The success of constrastive learning in single-label classifications motivates us to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Son D. Dao , Ethan Zhao , Dinh Phung , Jianfei Cai

Semi-Supervised Instance Segmentation (SSIS) involves classifying and grouping image pixels into distinct object instances using limited labeled data. This learning paradigm usually faces a significant challenge of unstable performance…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Jianghang Lin , Yilin Lu , Yunhang Shen , Chaoyang Zhu , Shengchuan Zhang , Liujuan Cao , Rongrong Ji

Existing Class Incremental Learning (CIL) methods are based on a supervised classification framework sensitive to data labels. When updating them based on the new class data, they suffer from catastrophic forgetting: the model cannot…

Machine Learning · Computer Science 2021-11-23 Zixuan Ni , Siliang Tang , Yueting Zhuang

Contrastive learning and self-supervised techniques have gained prevalence in computer vision for the past few years. It is essential for medical image analysis, which is often notorious for its lack of annotations. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Jun Li , Quan Quan , S. Kevin Zhou

Self-supervised learning (SSL) has demonstrated its effectiveness in learning representations through comparison methods that align with human intuition. However, mainstream SSL methods heavily rely on high body datasets with single label,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Jiale Chen
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