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Microfluidic devices offer numerous advantages in medical applications, including the capture of single cells in microwell-based platforms for genomic analysis. As the cost of sequencing decreases, the demand for high-throughput single-cell…

Computational Engineering, Finance, and Science · Computer Science 2024-09-13 Xueying Zhao , Yan Chen , Yuefu Jiang , Amie Radenbaugh , Jamie Moskwa , Devon Jensen

Biases in machine learning pose significant challenges, particularly when models amplify disparities that affect disadvantaged groups. Traditional bias mitigation techniques often lead to a {\itshape leveling-down effect}, whereby improving…

Machine Learning · Computer Science 2025-09-03 Lucas Mansilla , Rodrigo Echeveste , Camila Gonzalez , Diego H. Milone , Enzo Ferrante

Unlearning in large language models (LLMs) aims to remove specified data, but its efficacy is typically assessed with task-level metrics like accuracy and perplexity. We show that these metrics can be misleading, as models can appear to…

Computation and Language · Computer Science 2026-05-19 Xiaoyu Xu , Xiang Yue , Yang Liu , Qingqing Ye , Huadi Zheng , Peizhao Hu , Minxin Du , Haibo Hu

There has been a large number of studies in interpretable and explainable ML for cybersecurity, in particular, for intrusion detection. Many of these studies have significant amount of overlapping and repeated evaluations and analysis. At…

Cryptography and Security · Computer Science 2024-07-08 Omer Subasi , Johnathan Cree , Joseph Manzano , Elena Peterson

Causal modeling has been recognized as a potential solution to many challenging problems in machine learning (ML). Here, we describe how a recently proposed counterfactual approach developed to deconfound linear structural causal models can…

Machine Learning · Computer Science 2020-11-23 Elias Chaibub Neto

Imitation learning considerably simplifies policy synthesis compared to alternative approaches by exploiting access to expert demonstrations. For such imitation policies, errors away from the training samples are particularly critical. Even…

Machine Learning · Computer Science 2024-03-19 Kaustubh Sridhar , Souradeep Dutta , Dinesh Jayaraman , James Weimer , Insup Lee

Open-world machine learning (ML) combines closed-world models trained on in-distribution data with out-of-distribution (OOD) detectors, which aim to detect and reject OOD inputs. Previous works on open-world ML systems usually fail to test…

Machine Learning · Computer Science 2020-07-10 Liwei Song , Vikash Sehwag , Arjun Nitin Bhagoji , Prateek Mittal

Language Models (LMs) are prone to ''memorizing'' training data, including substantial sensitive user information. To mitigate privacy risks and safeguard the right to be forgotten, machine unlearning has emerged as a promising approach for…

Cryptography and Security · Computer Science 2025-06-11 Jiacheng Du , Zhibo Wang , Jie Zhang , Xiaoyi Pang , Jiahui Hu , Kui Ren

Concerns regarding fairness and bias have been raised in recent years due to the growing use of machine learning models in crucial decision-making processes, especially when it comes to delicate characteristics like gender. In order to…

Machine Learning · Computer Science 2024-08-30 Saish Shinde

Hidden confounding remains a central challenge in estimating treatment effects from observational data, as unobserved variables can lead to biased causal estimates. While recent work has explored the use of large language models (LLMs) for…

Computation and Language · Computer Science 2025-07-08 Hao Yang , Haoxuan Li , Luyu Chen , Haoxiang Wang , Xu Chen , Mingming Gong

Large Language Models (LLMs) offer extensive knowledge across various domains, but they may inadvertently memorize sensitive, unauthorized, or malicious data, such as personal information in the medical and financial sectors. Machine…

Computation and Language · Computer Science 2024-10-16 YuXuan Wu , Bonaventure F. P. Dossou , Dianbo Liu

Over the past decades, researchers and ML practitioners have come up with better and better ways to build, understand and improve the quality of ML models, but mostly under the key assumption that the training data is distributed…

Machine Learning · Computer Science 2019-10-14 Yeounoh Chung , Peter J. Haas , Eli Upfal , Tim Kraska

Performance monitoring of machine learning (ML)-based risk prediction models in healthcare is complicated by the issue of confounding medical interventions (CMI): when an algorithm predicts a patient to be at high risk for an adverse event,…

Machine Learning · Statistics 2023-04-17 Jean Feng , Alexej Gossmann , Gene Pennello , Nicholas Petrick , Berkman Sahiner , Romain Pirracchio

Deep learning models are effective, yet brittle. Even carefully trained, their behavior tends to be hard to predict when confronted with out-of-distribution samples. In this work, our goal is to propose a simple yet effective solution to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Gabriela Csurka , Tyler L. Hayes , Diane Larlus , Riccardo Volpi

Code quality is of paramount importance in all types of software development settings. Our work seeks to enable Machine Learning (ML) engineers to write better code by helping them find and fix instances of Data Leakage in their models.…

Software Engineering · Computer Science 2025-03-20 Eman Abdullah AlOmar , Catherine DeMario , Roger Shagawat , Brandon Kreiser

Machine learning (ML) has been pervasively researched nowadays and it has been applied in many aspects of real life. Nevertheless, issues of model and data still accompany the development of ML. For instance, training of traditional ML…

Machine Learning · Computer Science 2022-06-29 Shengwen Ding , Chenhui Hu

Machine learning (ML) is playing an increasingly important role in rendering decisions that affect a broad range of groups in society. ML models inform decisions in criminal justice, the extension of credit in banking, and the hiring…

Machine Learning · Computer Science 2022-07-14 Damien Dablain , Bartosz Krawczyk , Nitesh Chawla

Language models are deployed in settings that require compartmentalization: system prompts should not be disclosed, chain-of-thought reasoning is hidden from users, and sensitive data passes through shared contexts. We test whether models…

Cryptography and Security · Computer Science 2026-05-12 Ari Holtzman , Peter West

Forming a reliable judgement of a machine learning (ML) model's appropriateness for an application ecosystem is critical for its responsible use, and requires considering a broad range of factors including harms, benefits, and…

Machine Learning · Computer Science 2022-05-12 Ben Hutchinson , Negar Rostamzadeh , Christina Greer , Katherine Heller , Vinodkumar Prabhakaran

Learning under one-sided feedback (i.e., where we only observe the labels for examples we predicted positively on) is a fundamental problem in machine learning -- applications include lending and recommendation systems. Despite this, there…

Machine Learning · Computer Science 2020-10-14 Heinrich Jiang , Qijia Jiang , Aldo Pacchiano