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Two-level designs are widely used for screening experiments where the goal is to identify a few active factors which have major effects. Orthogonal two-level designs in which all factors are level-balance and each of the four level…

Methodology · Statistics 2025-04-08 Pi-Wen Tsai , Steven G. Gilmour

Optimal designs are required to make efficient statistical experiments. D-optimal designs for some models are calculated by using canonical moments. On the other hand, integrable systems are dynamical systems whose solutions can be written…

Methodology · Statistics 2012-11-06 Hiroto Sekido

In this paper, we study the quantum-state estimation problem in the framework of optimal design of experiments. We first find the optimal designs about arbitrary qubit models for popular optimality criteria such as A-, D-, and E-optimal…

Quantum Physics · Physics 2023-02-28 Jun Suzuki

We introduce a sketch-and-solve approach to speed up the Peng-Wei semidefinite relaxation of k-means clustering. When the data is appropriately separated we identify the k-means optimal clustering. Otherwise, our approach provides a…

Machine Learning · Computer Science 2022-11-30 Charles Clum , Dustin G. Mixon , Soledad Villar , Kaiying Xie

A typical problem in optimal design theory is finding an experimental design that is optimal with respect to some criteria in a class of designs. The most popular criteria include the A- and D-criteria. Regular graph designs occur in many…

Computation · Statistics 2015-04-20 Sera Aylin Cakiroglu

In this paper optimal designs for regression problems with spherical predictors of arbitrary dimension are considered. Our work is motivated by applications in material sciences, where crystallographic textures such as the missorientation…

Statistics Theory · Mathematics 2017-10-31 Holger Dette , Maria Konstantinou , Kirsten Schorning , Josua Gösmann

We construct supplementary difference sets (SDS) with parameters $(59;28,22;21)$, $(69;31,27;24)$, $(75;36,29;28)$, $(77;34,31;27)$ and $(87;38,36;31)$. These SDSs give D-optimal designs (DO-designs) of two-circulant type of orders…

Combinatorics · Mathematics 2017-10-12 Dragomir Z. Djokovic , Ilias S. Kotsireas

This work introduces a novel methodology based on finite mixtures of Student-t distributions to model the errors' distribution in linear regression models. The novelty lies on a particular hierarchical structure for the mixture distribution…

Methodology · Statistics 2017-11-15 Nívea B. da Silva , Marcos O. Prates , Flávio B. Gonçalves

Much of the work in the literature on optimal discrimination designs assumes that the models of interest are fully specified, apart from unknown parameters in some models. Recent work allows errors in the models to be non-normally…

Methodology · Statistics 2016-12-06 Holger Dette , Roman Guchenko , Viatcheslav Melas , Weng Kee Wong

For computing efficient approximate designs of multifactor experiments, we propose a simple algorithm based on adaptive exploration of the grid of all combinations of factor levels. We demonstrate that the algorithm significantly…

Computation · Statistics 2021-04-12 Radoslav Harman , Lenka Filová , Samuel Rosa

Finite mixture models have been widely used for the modelling and analysis of data from heterogeneous populations. Maximum likelihood estimation of the parameters is typically carried out via the Expectation-Maximization (EM) algorithm. The…

Computation · Statistics 2016-06-08 Sharon X Lee , Kaleb L Lee , Geoffrey J McLachlan

In a recent paper Dette et al. (2014) introduced optimal design problems for dose fnding studies with an active control. These authors concentrated on regression models with normal distributed errors (with known variance) and the problem of…

Methodology · Statistics 2014-11-03 Holger Dette , Katrin Kettelhake , Frank Bretz

In longitudinal studies, repeated measures are collected over time and hence they tend to be serially correlated. In this paper we consider an extension of skew-normal/independent linear mixed models introduced by Lachos et al. (2010),…

Methodology · Statistics 2021-01-19 Fernanda L. Schumacher , Victor H. Lachos , Larissa A. Matos

A mixture of common skew-t factor analyzers model is introduced for model-based clustering of high-dimensional data. By assuming common component factor loadings, this model allows clustering to be performed in the presence of a large…

Methodology · Statistics 2014-05-05 Paula M. Murray , Paul D. McNicholas , Ryan P. Browne

We give methods for the construction of designs for linear models, when the purpose of the investigation is the estimation of the conditional quantile function and the estimation method is quantile regression. The designs are robust against…

Methodology · Statistics 2014-12-01 Linglong Kong , Douglas P. Wiens

In a seminal paper \cite{studden1968} characterized $c$-optimal designs in regression models, where the regression functions form a Chebyshev system. He used these results to determine the optimal design for estimating the individual…

Statistics Theory · Mathematics 2019-06-21 Holger Dette , Viatcheslav B. Melas , Petr Shpilev

We consider the problem of designing experiments for the estimation of a target in regression analysis if there is uncertainty about the parametric form of the regression function. A new optimality criterion is proposed, which minimizes the…

Methodology · Statistics 2018-07-17 Kira Alhorn , Kirsten Schorning , Holger Dette

Under a generalised estimating equation analysis approach, approximate design theory is used to determine Bayesian D-optimal designs. For two examples, considering simple exchangeable and exponential decay correlation structures, we compare…

Methodology · Statistics 2024-02-16 Laura Etfer , James M. S. Wason , Michael J. Grayling

Mitscherlich's function is a well-known three-parameter non-linear regression function that quantifies the relation between a stimulus or a time variable and a response. Optimal designs for this function have been constructed only for…

Statistics Theory · Mathematics 2021-04-06 Maliheh Heidari , Md Abu Manju , Pieta C. IJzerman-Boon , Edwin R. van den Heuvel

The purpose of order-of-addition (OofA) experiments is to identify the best order in a sequence of m components in a system or treatment. Such experiments may be analysed by various regression models, the most popular ones being based on…

Methodology · Statistics 2021-01-27 Hans-Peter Piepho , Emlyn R. Williams
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