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We present a generally-applicable computational framework for the efficient and accurate characterization of molecular structural patterns and acid properties in explicit solvent using H$_2$O$_2$ and CH$_3$SO$_3$H in phenol as an example.…

One of the early weaknesses identified in deep neural networks trained for image classification tasks was their inability to provide low confidence predictions on out-of-distribution (OOD) data that was significantly different from the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Evelyn Mannix , Howard Bondell

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Out-of-distribution (OOD) detection is critical to ensuring the reliability of deep learning applications and has attracted significant attention in recent years. A rich body of literature has emerged to develop efficient score functions…

Machine Learning · Computer Science 2025-07-22 Yuhang Liu , Yuefei Wu , Bin Shi , Bo Dong

Neural networks are often utilised in critical domain applications (e.g. self-driving cars, financial markets, and aerospace engineering), even though they exhibit overconfident predictions for ambiguous inputs. This deficiency demonstrates…

Machine Learning · Computer Science 2023-01-03 John Mitros , Brian Mac Namee

Distributional data analysis, concerned with statistical analysis and modeling for data objects consisting of random probability density functions (PDFs) in the framework of functional data analysis (FDA), has received considerable interest…

Methodology · Statistics 2021-10-05 Xinyi Lei , Zhicheng Chen , Hui Li

Out of distribution (OOD) detection is a crucial part of making machine learning systems robust. The ImageNet-O dataset is an important tool in testing the robustness of ImageNet trained deep neural networks that are widely used across a…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Anugya Srivastava , Shriya Jain , Mugdha Thigle

Our goal is to perform out-of-distribution (OOD) detection, i.e., to detect when a robot is operating in environments drawn from a different distribution than the ones used to train the robot. We leverage Probably Approximately Correct…

Robotics · Computer Science 2023-11-08 Alec Farid , Sushant Veer , Divyanshu Pachisia , Anirudha Majumdar

Deep neural networks are often considered opaque systems, prompting the need for explainability methods to improve trust and accountability. Existing approaches typically attribute test-time predictions either to input features (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Aziz Bacha , Thomas George

Out-of-distribution (OOD) detection aims to identify test examples that do not belong to the training distribution and are thus unlikely to be predicted reliably. Despite a plethora of existing works, most of them focused only on the…

Machine Learning · Computer Science 2023-11-07 Reza Averly , Wei-Lun Chao

We show that the information gained in spectroscopic experiments regarding the number and distribution of atomic environments can be used as a valuable constraint in the refinement of the atomic-scale structures of nanostructured or…

Materials Science · Physics 2015-05-14 Matthew J Cliffe , Martin T. Dove , D. A. Drabold , Andrew L. Goodwin

Federated learning is a machine learning paradigm in which multiple devices collaboratively train a model under the supervision of a central server while ensuring data privacy. However, its performance is often hindered by redundant,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Emre Ardıç , Yakup Genç

In this paper, we consider the problem of extraction of most informative features from time series that are regarded as observed values of stochastic processes satisfying the It{\^{o}} stochastic differential equations with unknown random…

Two-dimensional (2D) materials and heterostructures exhibit unique physical properties, necessitating efficient and accurate characterization methods. Leveraging advancements in artificial intelligence, we introduce a deep learning-based…

Machine Learning · Computer Science 2025-03-04 Junqi He , Yujie Zhang , Jialu Wang , Tao Wang , Pan Zhang , Chengjie Cai , Jinxing Yang , Xiao Lin , Xiaohui Yang

Data outside the problem domain poses significant threats to the security of AI-based intelligent systems. Aiming to investigate the data domain and out-of-distribution (OOD) data in AI quality management (AIQM) study, this paper proposes…

Artificial Intelligence · Computer Science 2023-10-13 Tinghui Ouyang , Isao Echizen , Yoshiki Seo

Effectively modeling phenomena present in highly nonlinear dynamical systems whilst also accurately quantifying uncertainty is a challenging task, which often requires problem-specific techniques. We present a novel, domain-agnostic…

Machine Learning · Statistics 2021-10-26 Thomas M. McDonald , Mauricio A. Álvarez

For a machine learning model deployed in real world scenarios, the ability of detecting out-of-distribution (OOD) samples is indispensable and challenging. Most existing OOD detection methods focused on exploring advanced training skills or…

Machine Learning · Computer Science 2024-02-16 Chao Chen , Zhihang Fu , Kai Liu , Ze Chen , Mingyuan Tao , Jieping Ye

As language models become more general purpose, increased attention needs to be paid to detecting out-of-distribution (OOD) instances, i.e., those not belonging to any of the distributions seen during training. Existing methods for…

Machine Learning · Computer Science 2024-07-19 Aryan Gulati , Xingjian Dong , Carlos Hurtado , Sarath Shekkizhar , Swabha Swayamdipta , Antonio Ortega

We present a novel deep learning (DL) approach to produce highly accurate predictions of macroscopic physical properties of solid solution binary alloys and magnetic systems. The major idea is to make use of the correlations between…

Computational Physics · Physics 2021-01-29 Massimiliano Lupo Pasini , Ying Wai Li , Junqi Yin , Jiaxin Zhang , Kipton Barros , Markus Eisenbach

Inferring parameters of macro-kinetic growth models, typically represented by Ordinary Differential Equations (ODE), from the experimental data is a crucial step in bioprocess engineering. Conventionally, estimates of the parameters are…

Machine Learning · Computer Science 2023-12-07 Maxim Borisyak , Stefan Born , Peter Neubauer , Mariano Nicolas Cruz-Bournazou