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The classical approach to analyze time-to-event data, e.g. in clinical trials, is to fit Kaplan-Meier curves yielding the treatment effect as the hazard ratio between treatment groups. Afterwards commonly a log-rank test is performed in…

Methodology · Statistics 2020-09-16 Kathrin Möllenhoff , Achim Tresch

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

Machine Learning · Computer Science 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas

Censoring is the central problem in survival analysis where either the time-to-event (for instance, death), or the time-tocensoring (such as loss of follow-up) is observed for each sample. The majority of existing machine learning-based…

Machine Learning · Statistics 2024-07-22 Weijia Zhang , Chun Kai Ling , Xuanhui Zhang

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

In the development of stochastic integration and the theory of semimartingales, Markov processes have been a constant source of inspiration. Despite this historical interweaving, it turned out that semimartingales should be considered the…

Probability · Mathematics 2022-11-29 Sebastian Rickelhoff , Alexander Schnurr

This two-part paper presents a new approach to predictive analysis for social processes. In Part I, we begin by identifying a class of social processes which are simultaneously important in applications and difficult to predict using…

Adaptation and Self-Organizing Systems · Physics 2016-11-17 Richard Colbaugh , Kristin Glass

In survival analysis, traditional models assume all individuals will eventually experience the event of interest. However, advances in therapeutics have led to multiple clinical contexts with potentially curative therapies, and in these…

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

Machine Learning · Computer Science 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

World models have emerged as a unifying paradigm for learning latent dynamics, simulating counterfactual futures, and supporting planning under uncertainty. In this paper, we argue that computational epidemiology is a natural and…

Machine Learning · Computer Science 2026-04-14 Zeeshan Memon , Yiqi Su , Christo Kurisummoottil Thomas , Walid Saad , Liang Zhao , Naren Ramakrishnan

These notes provide a review of basic stochastic population models including branching processes and models of population genetics. Measure-valued population models including superprocesses and Fleming-Viot processes are also introduced…

Probability · Mathematics 2017-05-11 Donald A. Dawson

Data on count processes arise in a variety of applications, including longitudinal, spatial and imaging studies measuring count responses. The literature on statistical models for dependent count data is dominated by models built from…

Methodology · Statistics 2013-10-08 Antonio Canale , David B. Dunson

Data scientists and statisticians are often at odds when determining the best approach, machine learning or statistical modeling, to solve an analytics challenge. However, machine learning and statistical modeling are more cousins than…

Machine Learning · Computer Science 2022-01-10 Michele Bennett , Karin Hayes , Ewa J. Kleczyk , Rajesh Mehta

This study examines machine learning methods used in crisis management. Analyzing detected patterns from a crisis involves the collection and evaluation of historical or near-real-time datasets through automated means. This paper utilized…

Machine Learning · Computer Science 2025-02-11 Izunna Okpala , Shane Halse , Jess Kropczynski

We consider the problem of model building for rare events prediction in longitudinal follow-up studies. In this paper, we compare several resampling methods to improve standard regression models on a real life example. We evaluate the…

Methodology · Statistics 2023-06-21 Pierre Druilhet , Mathieu Berthe , Stéphanie Léger

SARS-COV-19 is the most prominent issue which many countries face today. The frequent changes in infections, recovered and deaths represents the dynamic nature of this pandemic. It is very crucial to predict the spreading rate of this virus…

Populations and Evolution · Quantitative Biology 2023-02-01 Sadhana Tiwari , Ritesh Chandra , Sonali Agarwal

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

Machine Learning · Computer Science 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

This report summarizes the discussions and conclusions of a 2-day multidisciplinary workshop that brought together researchers and practitioners in healthcare, computer science, and social sciences to explore what lessons were learned and…

Computers and Society · Computer Science 2024-03-04 David Danks , Rada Mihalcea , Katie Siek , Mona Singh , Brian Dixon , Haley Griffin

We consider a parametric modelling approach for survival data where covariates are allowed to enter the model through multiple distributional parameters, i.e., scale and shape. This is in contrast with the standard convention of having a…

Methodology · Statistics 2021-11-17 Fatima-Zahra Jaouimaa , Il Do Ha , Kevin Burke