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Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Quantum machine learning algorithms, the extensions of machine learning to quantum regimes, are believed to be more powerful as they leverage the power of quantum properties. Quantum machine learning methods have been employed to solve…

Computational Physics · Physics 2021-06-01 Shree Hari Sureshbabu , Manas Sajjan , Sangchul Oh , Sabre Kais

We have developed two quantum classifier models for the $t\bar{t}H(b\bar{b})$ classification problem, both of which fall into the category of hybrid quantum-classical algorithms for Noisy Intermediate Scale Quantum devices (NISQ). Our…

Kernel function plays a crucial role in machine learning algorithms such as classifiers. In this paper, we aim to improve the classification performance and reduce the reading out burden of quantum classifiers. We devise a universally…

Quantum Physics · Physics 2025-05-08 Li Xu , Xiao-yu Zhang , Ming Li , Shu-qian Shen

Quantum computers can theoretically have significant acceleration over classical computers; but, the near-future era of quantum computing is limited due to small number of qubits that are also error prone. Quilt is a framework for…

Quantum Physics · Physics 2023-09-27 Daniel Silver , Tirthak Patel , Devesh Tiwari

To accelerate learning process with few samples, meta-learning resorts to prior knowledge from previous tasks. However, the inconsistent task distribution and heterogeneity is hard to be handled through a global sharing model…

Machine Learning · Computer Science 2022-06-22 Geng Li , Boyuan Ren , Hongzhi Wang

The field of quantum machine learning is a promising way to lead to a revolution in intelligent data processing methods. In this way, a hybrid learning method based on classic kernel methods is proposed. This proposal also requires the…

Quantum Physics · Physics 2024-11-01 Jhordan Silveira de Borba , Jonas Maziero

Quantum embedding learning is an important step in the application of quantum machine learning to classical data. In this paper we propose a quantum few-shot embedding learning paradigm, which learns embeddings useful for training…

Quantum Physics · Physics 2023-01-31 Minzhao Liu , Junyu Liu , Rui Liu , Henry Makhanov , Danylo Lykov , Anuj Apte , Yuri Alexeev

The integration of quantum computing and machine learning has emerged as a promising frontier in computational science. We present a hybrid protocol which combines classical neural networks with non-equilibrium dynamics of a quantum…

Quantum Physics · Physics 2025-07-21 Ruiyang Zhou , Saubhik Sarkar , Sougato Bose , Abolfazl Bayat

Quantum machine learning, as an extension of classical machine learning that harnesses quantum mechanics, facilitates effiient learning from data encoded in quantum states. Training a quantum neural network typically demands a substantial…

Quantum Physics · Physics 2026-02-17 Yongcheng Ding , Yue Ban , Mikel Sanz , José D. Martín-Guerrero , Xi Chen

Classical machine learning theory and theory of quantum computations are among of the most rapidly developing scientific areas in our days. In recent years, researchers investigated if quantum computing can help to improve classical machine…

Quantum Physics · Physics 2019-06-26 D. V. Fastovets , Yu. I. Bogdanov , B. I. Bantysh , V. F. Lukichev

Quantum-enhanced machine learning is a rapidly evolving field that aims to leverage the unique properties of quantum mechanics to enhance classical machine learning. However, the practical applicability of these methods remains an open…

Quantum Physics · Physics 2025-02-18 Diego Alvarez-Estevez

We investigate ensemble methods for prediction in an online setting. Unlike all the literature in ensembling, for the first time, we introduce a new approach using a meta learner that effectively combines the base model predictions via…

Machine Learning · Computer Science 2022-12-01 Arda Fazla , Mustafa Enes Aydin , Orhun Tamyigit , Suleyman Serdar Kozat

Protein-ligand binding affinity is critical in drug discovery, but experimentally determining it is time-consuming and expensive. Artificial intelligence (AI) has been used to predict binding affinity, significantly accelerating this…

Emerging Technologies · Computer Science 2025-09-16 Seon-Geun Jeong , Kyeong-Hwan Moon , Won-Joo Hwang

Model selection is a strategy aimed at creating accurate and robust models. A key challenge in designing these algorithms is identifying the optimal model for classifying any particular input sample. This paper addresses this challenge and…

Machine Learning · Computer Science 2023-05-22 James Kotary , Vincenzo Di Vito , Ferdinando Fioretto

This research introduces a novel methodology for optimizing Bayesian Neural Networks (BNNs) by synergistically integrating them with traditional machine learning algorithms such as Random Forests (RF), Gradient Boosting (GB), and Support…

Machine Learning · Computer Science 2023-10-10 Peiwen Tan

Image classification, a pivotal task in multiple industries, faces computational challenges due to the burgeoning volume of visual data. This research addresses these challenges by introducing two quantum machine learning models that…

Quantum Physics · Physics 2024-03-29 Arsenii Senokosov , Alexandr Sedykh , Asel Sagingalieva , Basil Kyriacou , Alexey Melnikov

Due to the immense potential of quantum computers and the significant computing overhead required in machine learning applications, the variational quantum classifier (VQC) has received a lot of interest recently for image classification.…

Quantum Physics · Physics 2022-12-20 Ruiyang Qin , Zhiding Liang , Jinglei Cheng , Peter Kogge , Yiyu Shi

In recent years, advanced deep neural networks have required a large number of parameters for training. Therefore, finding a method to reduce the number of parameters has become crucial for achieving efficient training. This work proposes a…

A central challenge in quantum computing is to identify more computational problems for which utilization of quantum resources can offer significant speedup. Here, we propose a hybrid quantum-classical scheme to tackle the quantum optimal…

Quantum Physics · Physics 2017-04-19 Jun Li , Xiaodong Yang , Xinhua Peng , Chang-Pu Sun
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