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Despite much recent work, the true promise and limitations of the Quantum Alternating Operator Ansatz (QAOA) are unclear. A critical question regarding QAOA is to what extent its performance scales with the input size of the problem…

Quantum Physics · Physics 2023-12-07 John Golden , Andreas Bärtschi , Stephan Eidenbenz , Daniel O'Malley

Applications such as simulating complicated quantum systems or solving large-scale linear algebra problems are very challenging for classical computers due to the extremely high computational cost. Quantum computers promise a solution,…

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

The study of quantum computation has been motivated by the hope of finding efficient quantum algorithms for solving classically hard problems. In this context, quantum algorithms by local adiabatic evolution have been shown to solve an…

Quantum Physics · Physics 2009-11-10 Jérémie Roland , Nicolas J. Cerf

This paper introduces the use of tailored variational forms for variational quantum eigensolver that have properties of representing certain constraints on the search domain of a linear constrained quadratic binary optimization problem…

Quantum Physics · Physics 2020-11-30 Miguel Paredes Quinones , Catarina Junqueira

Optimization problems are ubiquitous in various industrial settings, and multi-knapsack optimization is one recurrent task faced daily by several industries. The advent of quantum computing has opened a new paradigm for computationally…

Variational quantum algorithms offer fascinating prospects for the solution of combinatorial optimization problems using digital quantum computers. However, the achievable performance in such algorithms and the role of quantum correlations…

Quantum Physics · Physics 2024-01-10 Gopal Chandra Santra , Fred Jendrzejewski , Philipp Hauke , Daniel J. Egger

Quantum computers are expected to accelerate solving combinatorial optimization problems, including algorithms such as Grover adaptive search and quantum approximate optimization algorithm (QAOA). However, many combinatorial optimization…

Quantum Physics · Physics 2023-05-05 Takuya Yoshioka , Keita Sasada , Yuichiro Nakano , Keisuke Fujii

The Quantum Approximate Optimization Algorithm (QAOA) is a hybrid quantum-classical variational algorithm designed to tackle combinatorial optimization problems. Despite its promise for near-term quantum applications, not much is currently…

Quantum Physics · Physics 2020-06-26 Leo Zhou , Sheng-Tao Wang , Soonwon Choi , Hannes Pichler , Mikhail D. Lukin

Optimization problems become fundamentally challenging as the number of variables increases. Because the volume of the search space grows exponentially, classical algorithms frequently fail to locate the global minimum of non-convex…

Quantum Physics · Physics 2026-04-23 Dominik Soós , Marc Paterno , John Stenger , Nikos Chrisochoides

Given their potential to demonstrate near-term quantum advantage, variational quantum algorithms (VQAs) have been extensively studied. Although numerous techniques have been developed for VQA parameter optimization, it remains a significant…

Quantum Physics · Physics 2024-06-05 Zichang He , Bo Peng , Yuri Alexeev , Zheng Zhang

Quantum enhanced optimization of classical cost functions is a central theme of quantum computing due to its high potential value in science and technology. The variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2024-11-27 Giuseppe Scriva , Nikita Astrakhantsev , Sebastiano Pilati , Guglielmo Mazzola

Quadratic Unconstrained Binary Optimization (QUBO) is a broad class of optimization problems with many practical applications. To solve its hard instances in an exact way, known classical algorithms require exponential time and several…

Quantum Physics · Physics 2021-01-21 Gian Giacomo Guerreschi

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

The efficient management of energy communities relies on the solution of the "prosumer problem", i.e., the problem of scheduling the household loads on the basis of the user needs, the electricity prices, and the availability of local…

Quantum Physics · Physics 2023-11-20 Carlo Mastroianni , Francesco Plastina , Luigi Scarcello , Jacopo Settino , Andrea Vinci

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithmic framework for finding approximate solutions to combinatorial optimization problems, derived from an approximation to the Quantum Adiabatic Algorithm (QAA). In solving…

Quantum Physics · Physics 2020-02-05 Yue Ruan , Samuel Marsh , Xilin Xue , Xi Li , Zhihao Liu , Jingbo Wang

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

Quantum Physics · Physics 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

As power systems expand, solving the Unit Commitment Problem (UCP) becomes increasingly challenging due to the dimensional catastrophe, and traditional methods often struggle to balance computational efficiency and solution quality. To…

Systems and Control · Electrical Eng. & Systems 2025-03-27 Jingxian Zhou , Ziqing Zhu , Linghua Zhu , Siqi Bu

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

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