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Deep generative models of 3D shapes have received a great deal of research interest. Yet, almost all of them generate discrete shape representations, such as voxels, point clouds, and polygon meshes. We present the first 3D generative model…

Computer Vision and Pattern Recognition · Computer Science 2021-08-17 Rundi Wu , Chang Xiao , Changxi Zheng

Data-driven generative modeling has made remarkable progress by leveraging the power of deep neural networks. A reoccurring challenge is how to enable a model to generate a rich variety of samples from the entire target distribution, rather…

Graphics · Computer Science 2019-09-04 Nadav Schor , Oren Katzir , Hao Zhang , Daniel Cohen-Or

One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Steve Kommrusch , Louis-Noël Pouchet

Understanding the structure and motion of the heart is crucial for diagnosing and managing cardiovascular diseases, the leading cause of global death. There is wide variation in cardiac shape and motion patterns, influenced by demographic,…

Artificial Intelligence · Computer Science 2025-06-03 Mengyun Qiao , Kathryn A McGurk , Shuo Wang , Paul M. Matthews , Declan P O Regan , Wenjia Bai

Machine learning in drug discovery has been focused on virtual screening of molecular libraries using discriminative models. Generative models are an entirely different approach that learn to represent and optimize molecules in a continuous…

Quantitative Methods · Quantitative Biology 2020-11-17 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Surgical planning and training based on machine learning requires a large amount of 3D anatomical models reconstructed from medical imaging, which is currently one of the major bottlenecks. Obtaining these data from real patients and during…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Ann-Sophia Müller , Moonkwang Jeong , Meng Zhang , Jiyuan Tian , Arkadiusz Miernik , Stefanie Speidel , Tian Qiu

This survey provides a comprehensive review on recent advancements of generative learning models in robotic manipulation, addressing key challenges in the field. Robotic manipulation faces critical bottlenecks, including significant…

One of the most promising developments in computer vision in recent years is the use of generative neural networks for functionality condition-based 3D design reconstruction and generation. Here, neural networks learn dependencies between…

Machine Learning · Computer Science 2023-11-08 Christoph Petroll , Sebastian Eilermann , Philipp Hoefer , Oliver Niggemann

Deep generative models have gained much attention given their ability to generate data for applications as varied as healthcare to financial technology to surveillance, and many more - the most popular models being generative adversarial…

Cryptography and Security · Computer Science 2021-12-02 Hui Sun , Tianqing Zhu , Zhiqiu Zhang , Dawei Jin. Ping Xiong , Wanlei Zhou

In medical imaging, generative models are increasingly relied upon for two distinct but equally critical tasks: reconstruction, where the goal is to restore medical imaging (usually inverse problems like inpainting or superresolution), and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Niklas Bubeck , Yundi Zhang , Suprosanna Shit , Daniel Rueckert , Jiazhen Pan

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

In recent years, deep learning based generative models, particularly Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), and Diffusion Models (DMs), have been instrumental in in generating diverse, high-quality content…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Shamim Yazdani , Akansha Singh , Nripsuta Saxena , Zichong Wang , Avash Palikhe , Deng Pan , Umapada Pal , Jie Yang , Wenbin Zhang

Neural generative models can be used to learn complex probability distributions from data, to sample from them, and to produce probability density estimates. We propose a computational framework for developing neural generative models…

Machine Learning · Computer Science 2022-01-06 Alexander Ororbia , Daniel Kifer

Learning 3D+t shape completion and generation from multi-view cardiac magnetic resonance (CMR) images requires a large amount of high-resolution 3D whole-heart segmentations (WHS) to capture shape priors. In this work, we leverage flow…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Qiang Ma , Qingjie Meng , Mengyun Qiao , Paul M. Matthews , Declan P. O'Regan , Wenjia Bai

Generative models using neural network have opened a door to large-scale studies for various application domains, especially for studies that suffer from lack of real samples to obtain statistically robust inference. Typically, these…

Computer Vision and Pattern Recognition · Computer Science 2018-12-12 Seong Jae Hwang , Zirui Tao , Won Hwa Kim , Vikas Singh

Advancements in 3D vision have increased the impact of blood vessel modeling on medical applications. However, accurately representing the complex geometry and topology of blood vessels remains a challenge due to their intricate branching…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Siqi Chen , Guoqing Zhang , Jiahao Lai , Bingzhi Shen , Sihong Zhang , Caixia Dong , Xuejin Chen , Yang Li

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

GenerateCT, the first approach to generating 3D medical imaging conditioned on free-form medical text prompts, incorporates a text encoder and three key components: a novel causal vision transformer for encoding 3D CT volumes, a text-image…

Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic. In clinical practice it is frequently common to acquire only sparse data (e.g. individual slices)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Benjamin Hou , Athanasios Vlontzos , Amir Alansary , Daniel Rueckert , Bernhard Kainz

The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Haoshen Wang , Zhentao Liu , Kaicong Sun , Xiaodong Wang , Dinggang Shen , Zhiming Cui