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The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Yunan Wu , Francisco M. Castro-Macías , Pablo Morales-Álvarez , Rafael Molina , Aggelos K. Katsaggelos

Deep learning has achieved remarkable success in medical image classification. However, its clinical application is often hindered by data heterogeneity caused by variations in scanner vendors, imaging protocols, and operators. Approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yaoyao Zhu , Xiuding Cai , Yingkai Wang , Yu Yao , Xu Luo , Zhongliang Fu

Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Krzysztof Maziarz , Anna Krason , Zbigniew Wojna

Automated retinal disease diagnosis is vital given the rising prevalence of conditions such as diabetic retinopathy and macular degeneration. Conventional deep learning approaches require large annotated datasets, which are costly and often…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Jasmaine Khale , Ravi Prakash Srivastava

Reliable automatic diagnosis of Diabetic Retinopathy (DR) and Macular Edema (ME) is an invaluable asset in improving the rate of monitored patients among at-risk populations and in enabling earlier treatments before the pathology progresses…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Gabriel Lepetit-Aimon , Clément Playout , Marie Carole Boucher , Renaud Duval , Michael H Brent , Farida Cheriet

Purpose: To demonstrate that retinal microvasculature per se is a reliable biomarker for Diabetic Retinopathy (DR) and, by extension, cardiovascular diseases. Methods: Deep Learning Convolutional Neural Networks (CNN) applied to color…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Anusua Trivedi , Jocelyn Desbiens , Ron Gross , Sunil Gupta , Rahul Dodhia , Juan Lavista Ferres

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Referring image segmentation (RIS) aims to segment a particular region based on a language expression prompt. Existing methods incorporate linguistic features into visual features and obtain multi-modal features for mask decoding. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Mengxi Zhang , Yiming Liu , Xiangjun Yin , Huanjing Yue , Jingyu Yang

In many review classification applications, a fine-grained analysis of the reviews is desirable, because different segments (e.g., sentences) of a review may focus on different aspects of the entity in question. However, training supervised…

Machine Learning · Computer Science 2019-10-02 Giannis Karamanolakis , Daniel Hsu , Luis Gravano

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

DRDr II is a hybrid of machine learning and deep learning worlds. It builds on the successes of its antecedent, namely, DRDr, that was trained to detect, locate, and create segmentation masks for two types of lesions (exudates and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , M. Hadi Amini , Hamid R. Arabnia

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

The application of Artificial Intelligence in the medical market brings up increasing concerns but aids in more timely diagnosis of silent progressing diseases like Diabetic Retinopathy. In order to diagnose Diabetic Retinopathy (DR),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Sharan Subramanian , Leilani H. Gilpin

Semi-supervised semantic segmentation aims to learn from a small amount of labeled data and plenty of unlabeled ones for the segmentation task. The most common approach is to generate pseudo-labels for unlabeled images to augment the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Rui Chen , Tao Chen , Qiong Wang , Yazhou Yao

Multi-instance learning (MIL) is a form of weakly supervised learning where a single class label is assigned to a bag of instances while the instance-level labels are not available. Training classifiers to accurately determine the bag label…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Bin Li , Kevin W. Eliceiri

Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology.…

Machine Learning · Computer Science 2019-02-13 Rony Gelman
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