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We discuss the possibility of multiple underlying etiologies of the condition currently labeled as schizophrenia. We support this hypothesis with a theoretical model of the prefrontal-limbic system. We show how the dynamical behavior of…

Neurons and Cognition · Quantitative Biology 2008-08-19 Anca Radulescu

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially…

For the early identification, diagnosis, and treatment of mental health illnesses, the integration of deep learning (DL) and machine learning (ML) has started playing a significant role. By evaluating complex data from imaging, genetics,…

Alzheimer's Disease (AD) is a neurodegenerative disease that is one of the significant causes of death in the elderly population. Many deep learning techniques have been proposed to diagnose AD using Magnetic Resonance Imaging (MRI) scans.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 A. H. Rashid , A. Gupta , J. Gupta , M. Tanveer

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

Image and Video Processing · Electrical Eng. & Systems 2019-01-30 GuruRaj Awate

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Finding the biomarkers associated with ASD is extremely helpful to understand the underlying roots of the disorder and can lead to earlier diagnosis and more targeted…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James S. Duncan

The advent of deep learning has significantly propelled the capabilities of automated medical image diagnosis, providing valuable tools and resources in the realm of healthcare and medical diagnostics. This research delves into the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Ryan Donghan Kwon , Dohyun Lim , Yoonha Lee , Seung Won Lee

Multimodal schizophrenia assessment systems have gained traction over the last few years. This work introduces a schizophrenia assessment system to discern between prominent symptom classes of schizophrenia and predict an overall…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-19 Gowtham Premananth , Carol Espy-Wilson

We investigate the generalizability of deep convolutional neural network (CNN) on the task of disease classification from chest x-rays collected over multiple sites. We systematically train the model using datasets from three independent…

Quantitative Methods · Quantitative Biology 2020-10-26 Nabit Bajwa , Kedar Bajwa , Atif Rana , M. Faique Shakeel , Kashif Haqqi , Suleiman Ali Khan

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

The accurate classification of mass lesions in the adrenal glands (adrenal masses), detected with computed tomography (CT), is important for diagnosis and patient management. Adrenal masses can be benign or malignant and benign masses have…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Lei Bi , Jinman Kim , Tingwei Su , Michael Fulham , David Dagan Feng , Guang Ning

This review systematizes the emerging literature for causal inference using deep neural networks under the potential outcomes framework. It provides an intuitive introduction on how deep learning can be used to estimate/predict…

Machine Learning · Computer Science 2023-11-30 Bernard Koch , Tim Sainburg , Pablo Geraldo , Song Jiang , Yizhou Sun , Jacob Gates Foster

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

Machine Learning · Computer Science 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that…

Machine Learning · Computer Science 2023-08-23 Nathan Zhong , Nikhil Yadav

Social media has become an important source for understanding mental health, providing researchers with a way to detect conditions like depression from user-generated posts. This tutorial provides practical guidance to address common…

Computation and Language · Computer Science 2025-08-06 Yeyubei Zhang , Zhongyan Wang , Zhanyi Ding , Yexin Tian , Jianglai Dai , Xiaorui Shen , Yunchong Liu , Yuchen Cao

Digital phenotyping in mental health often consists of collecting behavioral and experience-based information through sensory and self-reported data from devices such as smartphones. Such rich and comprehensive data could be used to develop…

Social and Information Networks · Computer Science 2023-12-05 Andy Davies , Eiko Fried , Hane Aung , Omar Costilla-Reyes

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Single-subject mapping of resting-state brain functional activity to non-imaging phenotypes is a major goal of neuroimaging. The large majority of learning approaches applied today rely either on static representations or on short-term…

Machine Learning · Computer Science 2022-08-09 Ahmed El-Gazzar , Rajat Mani Thomas , Guido Van Wingen