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Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Schizophrenia is a severe yet treatable mental disorder, it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms, therefore there is a need for…

Human-Computer Interaction · Computer Science 2023-10-26 Niki Maria Foteinopoulou , Ioannis Patras

Schizophrenia is a debilitating, chronic mental disorder that significantly impacts an individual's cognitive abilities, behavior, and social interactions. It is characterized by subtle morphological changes in the brain, particularly in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince Calhoun , Dong Hye Ye

Schizophrenia is a severe mental health condition that requires a long and complicated diagnostic process. However, early diagnosis is vital to control symptoms. Deep learning has recently become a popular way to analyse and interpret…

Machine Learning · Computer Science 2022-04-01 Daniel Organisciak , Hubert P. H. Shum , Ephraim Nwoye , Wai Lok Woo

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner

Machine learning is employed in healthcare to draw approximate conclusions regarding human diseases and mental health problems. Compared to older traditional methods, it can help to analyze data more efficiently and produce better and more…

Neurons and Cognition · Quantitative Biology 2023-05-25 Narges Ramesh , Yasmin Ghodsi , Hamidreza Bolhasani

Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Mengjiao Hu , Kang Sim , Juan Helen Zhou , Xudong Jiang , Cuntai Guan

Schizophrenia (SCZ) is a brain disorder where different people experience different symptoms, such as hallucination, delusion, flat-talk, disorganized thinking, etc. In the long term, this can cause severe effects and diminish life…

Machine Learning · Computer Science 2023-01-19 Shradha Verma , Tripti Goel , M Tanveer , Weiping Ding , Rahul Sharma , R Murugan

Deep reinforcement learning (DRL) algorithms have the potential to provide new insights into psychiatric disorders. Here we create a DRL model of schizophrenia: a complex psychotic disorder characterized by anhedonia, avoidance, temporal…

Neurons and Cognition · Quantitative Biology 2025-10-30 Xena Al-Hejji , Santina Duarte , Jose Guillermo Gomez Castro , Edgar Bermudez Contreras , Eric Chalmers

Schizophrenia is a complex psychiatric disorder involving changes in thought patterns, perception, mood, and behavior. The diagnosis of schizophrenia is challenging and requires that patients show two or more positive symptoms for at least…

Machine Learning · Computer Science 2021-02-17 Maritza Tynes , Mahboobeh Parsapoor

Studies on schizophrenia assessments using deep learning typically treat it as a classification task to detect the presence or absence of the disorder, oversimplifying the condition and reducing its clinical applicability. This traditional…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-29 Gowtham Premananth , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Deep learning has been successfully applied to recognizing both natural images and medical images. However, there remains a gap in recognizing 3D neuroimaging data, especially for psychiatric diseases such as schizophrenia and depression…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Mengjiao Hu , Xudong Jiang , Kang Sim , Juan Helen Zhou , Cuntai Guan

In this study, we leverage a deep learning-based method for the automatic diagnosis of schizophrenia using EEG brain recordings. This approach utilizes generative data augmentation, a powerful technique that enhances the accuracy of the…

Machine Learning · Computer Science 2024-07-18 Mehrshad Saadatinia , Armin Salimi-Badr

Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Rafael Castro , Ishaan Patel , Tarun Patanjali , Priya Iyer

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Yuhong Jiao , Jiaqing Miao , Jinnan Gong , Hui He , Ping Liang , Cheng Luo , Ying Tan

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Mental disorders are among the leading causes of disability worldwide. The first step in treating these conditions is to obtain an accurate diagnosis, but the absence of established clinical tests makes this task challenging. Machine…

Signal Processing · Electrical Eng. & Systems 2021-10-13 Caroline L. Alves , Aruane M. Pineda , Kirstin Roster , Christiane Thielemann , Francisco A. Rodrigues

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Objective: Schizophrenia seriously affects the quality of life. To date, both simple (linear discriminant analysis) and complex (deep neural network) machine learning methods have been utilized to identify schizophrenia based on functional…

Machine Learning · Computer Science 2021-05-11 Tian Wang , Anastasios Bezerianos , Andrzej Cichocki , Junhua Li

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This…

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