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Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Alain Jungo , Raphael Meier , Ekin Ermis , Marcela Blatti-Moreno , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

High-quality data is necessary for modern machine learning. However, the acquisition of such data is difficult due to noisy and ambiguous annotations of humans. The aggregation of such annotations to determine the label of an image leads to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Lars Schmarje , Vasco Grossmann , Claudius Zelenka , Sabine Dippel , Rainer Kiko , Mariusz Oszust , Matti Pastell , Jenny Stracke , Anna Valros , Nina Volkmann , Reinhard Koch

Accurate cell segmentation in pathology images typically requires dense pixel-wise annotations, which are costly and time-consuming to obtain. This challenge is especially important for emerging biological imaging modalities and multiplexed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gunjan Shrivastava , Saad Nadeem

Medical image segmentation annotations suffer from inter- and intra-observer variations even among experts due to intrinsic differences in human annotators and ambiguous boundaries. Leveraging a collection of annotators' opinions for an…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Zahra Mirikharaji , Kumar Abhishek , Saeed Izadi , Ghassan Hamarneh

Studies of writing revisions rarely focus on revision quality. To address this issue, we introduce a corpus of between-draft revisions of student argumentative essays, annotated as to whether each revision improves essay quality. We…

Computation and Language · Computer Science 2019-09-13 Tazin Afrin , Diane Litman

Obtaining annotations for complex computer vision tasks such as object detection is an expensive and time-intense endeavor involving a large number of human workers or expert opinions. Reducing the amount of annotations required while…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Marius Schubert , Tobias Riedlinger , Karsten Kahl , Matthias Rottmann

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Interactive segmentation plays a crucial role in accelerating the annotation, particularly in domains requiring specialized expertise such as nuclear medicine. For example, annotating lesions in whole-body Positron Emission Tomography (PET)…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Zdravko Marinov , Moon Kim , Jens Kleesiek , Rainer Stiefelhagen

We analyze the variability among segmentations of cranial blood vessels in 2D DSA performed by multiple annotators in order to characterize and quantify segmentation uncertainty. We use this analysis to quantify segmentation uncertainty and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-15 M. Geshvadi , G. So , D. D. Chlorogiannis , C. Galvin , E. Torio , A. Azimi , Y. Tachie-Baffour , N. Haouchine , A. Golby , M. Vangel , W. M. Wells , Y. Epelboym , R. Du , F. Durupinar , S. Frisken

Two of the most common tasks in medical imaging are classification and segmentation. Either task requires labeled data annotated by experts, which is scarce and expensive to collect. Annotating data for segmentation is generally considered…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Ozan Ciga , Anne L. Martel

Classification and differentiation of small pathological objects may greatly vary among human raters due to differences in training, expertise and their consistency over time. In a radiological setting, objects commonly have high…

Many machine learning systems today are trained on large amounts of human-annotated data. Data annotation tasks that require a high level of competency make data acquisition expensive, while the resulting labels are often subjective,…

Machine Learning · Computer Science 2020-04-08 Emmanouil Antonios Platanios , Maruan Al-Shedivat , Eric Xing , Tom Mitchell

Annotated datasets are an essential ingredient to train, evaluate, compare and productionalize supervised machine learning models. It is therefore imperative that annotations are of high quality. For their creation, good quality management…

Machine Learning · Computer Science 2024-05-30 Jan-Christoph Klie , Juan Haladjian , Marc Kirchner , Rahul Nair

Supervised Deep Learning has been highly successful in recent years, achieving state-of-the-art results in most tasks. However, with the ongoing uptake of such methods in industrial applications, the requirement for large amounts of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-18 Fabio De Sousa Ribeiro , Francesco Caliva , Mark Swainson , Kjartan Gudmundsson , Georgios Leontidis , Stefanos Kollias

Majority voting and averaging are common approaches employed to resolve annotator disagreements and derive single ground truth labels from multiple annotations. However, annotators may systematically disagree with one another, often…

Computation and Language · Computer Science 2021-10-13 Aida Mostafazadeh Davani , Mark Díaz , Vinodkumar Prabhakaran

Aggregating multiple annotations into a single ground truth label may hide valuable insights into annotator disagreement, particularly in tasks where subjectivity plays a crucial role. In this work, we explore methods for identifying…

Computation and Language · Computer Science 2025-09-09 Amir Homayounirad , Enrico Liscio , Tong Wang , Catholijn M. Jonker , Luciano C. Siebert

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Segmentation of anatomical structures is a fundamental image analysis task for many applications in the medical field. Deep learning methods have been shown to perform well, but for this purpose large numbers of manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Firat Ozdemir , Zixuan Peng , Philipp Fuernstahl , Christine Tanner , Orcun Goksel

The advancement of machine learning algorithms in medical image analysis requires the expansion of training datasets. A popular and cost-effective approach is automated annotation extraction from free-text medical reports, primarily due to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Veronika Cheplygina , Cathrine Damgaard , Trine Naja Eriksen , Dovile Juodelyte , Amelia Jiménez-Sánchez

Despite the remarkable performance of deep learning methods on various tasks, most cutting-edge models rely heavily on large-scale annotated training examples, which are often unavailable for clinical and health care tasks. The labeling…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Jialin Peng , Ye Wang
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