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Computed tomography (CT) samples with pathological annotations are difficult to obtain. As a result, the computer-aided diagnosis (CAD) algorithms are trained on small datasets (e.g., LIDC-IDRI with 1,018 samples), limiting their accuracies…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Penghua Zhai , Enwei Zhu , Baolian Qi , Xin Wei , Jinpeng Li

Algorithmic decision support is rapidly becoming a staple of personalized medicine, especially for high-stakes recommendations in which access to certain information can drastically alter the course of treatment, and thus, patient outcome;…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Haomin Chen , T. Y. Alvin Liu , Catalina Gomez , Zelia Correa , Mathias Unberath

Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring good feature representation from a limited number of data samples. In this paper, we applied CL to…

Machine Learning · Computer Science 2024-10-22 Anchen Sun , Elizabeth J. Franzmann , Zhibin Chen , Xiaodong Cai

Malignant melanoma is a common skin cancer that is mostly curable before metastasis -when growths spawn in organs away from the original site. Melanoma is the most dangerous type of skin cancer if left untreated due to the high risk of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Vidushi Meel , Asritha Bodepudi

Convolutional Neural Networks have demonstrated human-level performance in the classification of melanoma and other skin lesions, but evident performance disparities between differing skin tones should be addressed before widespread…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Peter J. Bevan , Amir Atapour-Abarghouei

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

Machine Learning · Computer Science 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

This study focuses on automatic skin cancer detection using a Meta-learning approach for dermoscopic images. The aim of this study is to explore the benefits of the generalization of the knowledge extracted from non-medical data in the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Sara I. Garcia

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2017-03-13 Wenhao Zhang , Liangcai Gao , Runtao Liu

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Mohs micrographic surgery (MMS) is the gold standard technique for removing high risk nonmelanoma skin cancer however, intraoperative histopathological examination demands significant time, effort, and professionality. The objective of this…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Abdurrahim Yilmaz , Serra Atilla Aydin , Deniz Temur , Furkan Yuceyalcin , Berkin Deniz Kahya , Rahmetullah Varol , Ozay Gokoz , Gulsum Gencoglan , Huseyin Uvet , Gonca Elcin

While skin cancer detection has been a valuable deep learning application for years, its evaluation has often neglected the context in which testing images are assessed. Traditional melanoma classifiers assume that their testing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nick DiSanto , Gavin Harding , Ethan Martinez , Benjamin Sanders

Cell identification within the H&E slides is an essential prerequisite that can pave the way towards further pathology analyses including tissue classification, cancer grading, and phenotype prediction. However, performing such a task using…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Ramin Nakhli , Amirali Darbandsari , Hossein Farahani , Ali Bashashati

Melanoma, the deadliest form of skin cancer, has seen a steady increase in incidence rates worldwide, posing a significant challenge to dermatologists. Early detection is crucial for improving patient survival rates. However, performing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Vullnet Useini , Stephanie Tanadini-Lang , Quentin Lohmeyer , Mirko Meboldt , Nicolaus Andratschke , Ralph P. Braun , Javier Barranco García

Skin cancer is a serious and potentially fatal disease caused by DNA damage. Early detection significantly increases survival rates, making accurate diagnosis crucial. In this groundbreaking study, we present a hybrid framework based on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Maksuda Akter , Rabea Khatun , Md. Alamin Talukder , Md. Manowarul Islam , Md. Ashraf Uddin

The spectacular response observed in clinical trials of immunotherapy in patients with previously uncurable Melanoma, a highly aggressive form of skin cancer, calls for a better understanding of the cancer-immune interface. Computational…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Konstantinos Zormpas-Petridis , Henrik Failmezger , Ioannis Roxanis , Matthew Blackledge , Yann Jamin , Yinyin Yuan