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Our goal is to bridge human and machine intelligence in melanoma detection. We develop a classification system exploiting a combination of visual pre-processing, deep learning, and ensembling for providing explanations to experts and to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Ellák Somfai , Benjámin Baffy , Kristian Fenech , Changlu Guo , Rita Hosszú , Dorina Korózs , Fabrizio Nunnari , Marcell Pólik , Daniel Sonntag , Attila Ulbert , András Lőrincz

Representation learning of pathology whole-slide images (WSIs) has primarily relied on weak supervision with Multiple Instance Learning (MIL). This approach leads to slide representations highly tailored to a specific clinical task.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Tim Lenz , Peter Neidlinger , Marta Ligero , Georg Wölflein , Marko van Treeck , Jakob Nikolas Kather

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Malignant melanoma is the deadliest form of skin cancer and, in recent years, is rapidly growing in terms of the incidence worldwide rate. The most effective approach to targeted treatment is early diagnosis. Deep learning algorithms,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 Mario Manzo , Simone Pellino

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ciro Listone , Aniello Murano

As the application of deep learning in dermatology continues to grow, the recognition of melanoma has garnered significant attention, demonstrating potential for improving diagnostic accuracy. Despite advancements in image classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rujosh Polma , Krishnan Menon Iyer

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 M Rita Verdelho , Alexandre Bernardino , Catarina Barata

The incidence of malignant melanoma continues to increase worldwide. This cancer can strike at any age; it is one of the leading causes of loss of life in young persons. Since this cancer is visible on the skin, it is potentially detectable…

Computer Vision and Pattern Recognition · Computer Science 2016-01-29 Nabin K. Mishra , M. Emre Celebi

This work seeks to determine how modern machine learning techniques may be applied to the previously unexplored topic of melanoma diagnostics using digital pathology. We curated a new dataset of 50 patient cases of cutaneous melanoma using…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Adon Phillips , Iris Teo , Jochen Lang

Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Hanadi El Achi , Tatiana Belousova , Lei Chen , Amer Wahed , Iris Wang , Zhihong Hu , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Convolutional Neural Networks have demonstrated dermatologist-level performance in the classification of melanoma from skin lesion images, but prediction irregularities due to biases seen within the training data are an issue that should be…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Peter J. Bevan , Amir Atapour-Abarghouei

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

The initial assessment of skin lesions is typically based on dermoscopic images. As this is a difficult and time-consuming task, machine learning methods using dermoscopic images have been proposed to assist human experts. Other approaches…

Computer Vision and Pattern Recognition · Computer Science 2020-02-06 Nils Gessert , Marcel Bengs , Alexander Schlaefer

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology help us to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Yi Cui , Yao Li , Jayson R. Miedema , Sherif Farag , J. S. Marron , Nancy E. Thomas

Deep learning has been a prevalence in computational chemistry and widely implemented in molecule property predictions. Recently, self-supervised learning (SSL), especially contrastive learning (CL), gathers growing attention for the…

Machine Learning · Computer Science 2022-06-01 Yuyang Wang , Rishikesh Magar , Chen Liang , Amir Barati Farimani

Whole Slide Image (WSI) representation is critical for cancer subtyping, cancer recognition and mutation prediction.Training an end-to-end WSI representation model poses significant challenges, as a standard gigapixel slide can contain tens…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Jing Jin , Xu Liu , Te Gao , Zhihong Shi , Yixiong Liang , Ruiqing Zheng , Hulin Kuang , Min Zeng , Shichao Kan