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The description of a conducting medium in thermal equilibrium, such as an electrolyte solution or a plasma, involves nonlinear electrostatics, a subject rarely discussed in the standard electricity and magnetism textbooks. We consider in…

Chemical Physics · Physics 2018-08-01 C. G. Gray , P. J. Stiles

We consider the nonlinear Poisson-Boltzmann equation in the context of electrostatic models for a biological macromolecule, embedded in a bounded domain containing a solution of an arbitrary number of ionic species which is not necessarily…

Analysis of PDEs · Mathematics 2022-04-26 José A. Iglesias , Svetoslav Nakov

Electrostatics is of paramount importance to chemistry, physics, biology, and medicine. The Poisson-Boltzmann (PB) theory is a primary model for electrostatic analysis. However, it is highly challenging to compute accurate PB electrostatic…

Chemical Physics · Physics 2023-12-20 Jiahui Chen , Yongjia Xu , Xin Yang , Zixuan Cang , Weihua Geng , Guo-Wei Wei

Thermodynamic properties of charge-stabilised colloidal suspensions are commonly modeled by implementing the mean-field Poisson-Boltzmann (PB) theory within a cell model. This approach models a bulk system by a single macroion, together…

Soft Condensed Matter · Physics 2015-05-18 Alan R. Denton

In this paper, we apply the range-separated (RS) tensor format [6] for the construction of new regularization scheme for the Poisson-Boltzmann equation (PBE) describing the electrostatic potential in biomolecules. In our approach, we use…

Numerical Analysis · Mathematics 2024-12-20 Peter Benner , Venera Khoromskaia , Boris Khoromskij , Cleophas Kweyu , Matthias Stein

The classical problem of two uniformly charged infinite planes in electrochemical equilibrium with an infinite monovalent salt reservoir is solved exactly at the mean-field nonlinear Poisson-Boltzmann (PB) level, including an explicit…

Soft Condensed Matter · Physics 2009-11-07 M. N. Tamashiro , H. Schiessel

It is well known that the number of particles should be scaled up to enable industrial scale simulation. The calculations are more computationally intensive when the motion of the surrounding fluid is considered. Besides the advances in…

Computational Physics · Physics 2014-07-28 Hao Zhang , F. Xavier Trias , Assensi Oliva , Dongmin Yang , Yuanqiang Tan , Shi Shu , Yong Sheng

We develop an immersed boundary (IB) method for modeling flows around fixed or moving rigid bodies that is suitable for a broad range of Reynolds numbers, including steady Stokes flow. The spatio-temporal discretization of the fluid…

Numerical Analysis · Mathematics 2016-03-02 B. Kallemov , A. Pal Singh Bhalla , B. E. Griffith , A. Donev

The mathematical theory of integrable Painleve/Toda type systems sheds new light on the behavior of solutions to the Poisson-Boltzmann equation for the potential due to a long rod-like macroion. We investigate here the case of symmetric…

Soft Condensed Matter · Physics 2009-11-11 G. Tellez , E. Trizac

We study theoretically the osmotic pressure of a suspension of charged objects (e.g., colloids, polyelectrolytes, clay platelets, etc.) dialyzed against an electrolyte solution using the cell model and linear Poisson-Boltzmann (PB) theory.…

Soft Condensed Matter · Physics 2009-11-07 Markus Deserno , Hans-Hennig von Grunberg

The behavior of electrolyte solutions close to a charged surface is studied theoretically. A modified Poisson-Boltzmann equation which takes into account the volume excluded by the ions in addition to the electrostatic interactions is…

Soft Condensed Matter · Physics 2007-05-23 I. Borukhov , D. Andelman , H. Orland

A widely used electrostatics model in the biomolecular modeling community, the nonlinear Poisson-Boltzmann equation, along with its finite element approximation, are analyzed in this paper. A regularized Poisson-Boltzmann equation is…

Numerical Analysis · Mathematics 2010-01-12 Long Chen , Michael Holst , Jinchao Xu

In this paper we propose a nonlinear elasticity model of macromolecular conformational change (deformation) induced by electrostatic forces generated by an implicit solvation model. The Poisson-Boltzmann equation for the electrostatic…

Analysis of PDEs · Mathematics 2010-01-12 Yongcheng Zhou , Michael Holst , James Andrew McCammon

Fluid-structure interactions are central to many bio-molecular processes, and they impose a great challenge for computational and modeling methods. In this paper, we consider the immersed boundary method (IBM) for biofluid systems, and to…

Numerical Analysis · Mathematics 2021-10-13 Yushuang Luo , Xiantao Li , Wenrui Hao

By identifying a norm capturing the effect of the forcing governed by the Poisson equation, we give a detailed spectrum analysis on the linearized Vlasov-Poisson-Boltzmann system around a global Maxwellian. It is shown that the electric…

Analysis of PDEs · Mathematics 2014-02-18 Hailiang Li , Tong Yang , Mingying Zhong

Wereportonanewmultiscalemethodapproachforthestudyofsystemswith wide separation of short-range forces acting on short time scales and long-range forces acting on much slower scales. We consider the case of the Poisson-Boltzmann equation that…

Computational Physics · Physics 2018-10-22 Giovanni Lapenta , Wei Jiang

Implicit-solvent models are widely used to study the electrostatics in dissolved biomolecules, which are parameterized using force fields. Standard force fields treat the charge distribution with point charges, however, other force fields…

Computational Physics · Physics 2018-10-10 Christopher D. Cooper

We formulate and analyze an adaptive algorithm for isogeometric analysis with hierarchical B-splines for weakly-singular boundary integral equations. We prove that the employed weighted-residual error estimator is reliable and converges at…

Numerical Analysis · Mathematics 2022-08-24 Gregor Gantner , Dirk Praetorius

We propose an immersed boundary scheme for the numerical resolution of the Complete Electrode Model in Electrical Impedance Tomography, that we use as a main ingredient in the resolution of inverse problems in medical imaging. Such method…

Numerical Analysis · Mathematics 2023-05-24 Jérémi Dardé , Niami Nasr , Lisl Weynans

The Linearized Poisson--Boltzmann (LPB) equation is a popular and widely accepted model for accounting solvent effects in computational (bio-) chemistry. In the present article we derive the analytical forces of the…

Numerical Analysis · Mathematics 2023-09-14 Abhinav Jha , Michele Nottoli , Aleksandr Mikhalev , Chaoyu Quan , Benjamin Stamm