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The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

The human brain is composed of distinct regions that are each associated with particular functions and distinct propensities for the control of neural dynamics. However, the relation between these functions and control profiles is poorly…

Neurons and Cognition · Quantitative Biology 2020-06-02 Evelyn Tang , Harang Ju , Graham L. Baum , David R. Roalf , Theodore D. Satterthwaite , Fabio Pasqualetti , Danielle S. Bassett

Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

Neurons and Cognition · Quantitative Biology 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner

Vehicle-centric perception plays a crucial role in many intelligent systems, including large-scale surveillance systems, intelligent transportation, and autonomous driving. Existing approaches lack effective learning of vehicle-related…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Wentao Wu , Xiao Wang , Chenglong Li , Jin Tang , Bin Luo

Accurately characterizing higher-order interactions of brain regions and extracting interpretable organizational patterns from Functional Magnetic Resonance Imaging data is crucial for brain disease diagnosis. Current graph-based deep…

Neurons and Cognition · Quantitative Biology 2026-03-16 Dengyi Zhao , Zhiheng Zhou , Guiying Yan , Dongxiao Yu , Xingqin Qi

The shape of the brain's white matter connections is relatively unexplored in diffusion MRI tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if the variability in…

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Neurons and Cognition · Quantitative Biology 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton

Computer-supported simulation enables a practical alternative for medical training purposes. This study investigates the co-occurrence of facial-recognition-derived emotions and socially shared regulation of learning (SSRL) interactions in…

Human-Computer Interaction · Computer Science 2025-10-21 Xiaoshan Huang , Tianlong Zhong , Haolun Wu , Yeyu Wang , Ethan Churchill , Xue Liu , David Williamson Shaffer

The development of robust and generalisable models for encoding the spatio-temporal dynamics of human brain activity is crucial for advancing neuroscientific discoveries. However, significant individual variation in the organisation of the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Simon Dahan , Logan Z. J. Williams , Yourong Guo , Daniel Rueckert , Emma C. Robinson

Brain activation and connectivity analyses in task-based functional magnetic resonance imaging (fMRI) experiments with multiple subjects are currently at the forefront of data-driven neuroscience. In such experiments, interest often lies in…

Applications · Statistics 2019-04-02 Daniel Spencer , Rajarshi Guhaniyogi , Raquel Prado

Machine learning head models (MLHMs) are developed to estimate brain deformation for early detection of traumatic brain injury (TBI). However, the overfitting to simulated impacts and the lack of generalizability caused by distributional…

People with Multiple Sclerosis (MS) complain of problems with hand dexterity and cognitive fatigue. However, in many cases, impairments are subtle and difficult to detect. Functional near-infrared spectroscopy (fNIRS) is a non-invasive…

Machine Learning · Computer Science 2025-09-29 Sadman Saumik Islam , Bruna Dalcin Baldasso , Davide Cattaneo , Xianta Jiang , Michelle Ploughman

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

Neurons and Cognition · Quantitative Biology 2015-05-01 Ibai Diez , Paolo Bonifazi , Iñaki Escudero , Beatriz Mateos , Miguel A. Muñoz , Sebastiano Stramaglia , Jesus M. Cortes

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

Methodology · Statistics 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

In recent years, network analyses have been used to evaluate brain reorganization following stroke. However, many studies have often focused on single topological scales, leading to an incomplete model of how focal brain lesions affect…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Floriana Pichiorri , Giovanni Morone , Marco Molinari , Fabio Babiloni , Febo Cincotti , Donatella Mattia

Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However…

Emerging Technologies · Computer Science 2013-01-03 Nivedita Daimiwal , M. Sundhararajan , Revati Shriram

The advancement of machine learning algorithms has opened a wide scope for vibration-based SHM (Structural Health Monitoring). Vibration-based SHM is based on the fact that damage will alter the dynamic properties viz., structural response,…

Machine Learning · Computer Science 2019-08-20 Rahul Vashisht , H. Viji , T. Sundararajan , D. Mohankumar , S. Sumitra

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always…

Quantitative Methods · Quantitative Biology 2024-05-14 Anton Orlichenko , Gang Qu , Ziyu Zhou , Anqi Liu , Hong-Wen Deng , Zhengming Ding , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia
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