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We propose a Bayesian vector autoregressive (VAR) model for mixed-frequency data. Our model is based on the mean-adjusted parametrization of the VAR and allows for an explicit prior on the 'steady states' (unconditional means) of the…

Econometrics · Economics 2019-11-22 Sebastian Ankargren , Måns Unosson , Yukai Yang

Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective connectivity, which summarizes the directional neural…

Methodology · Statistics 2026-04-02 Haiyue Song , Ani Eloyan , Youjin Lee

Motivated by spectral analysis of replicated brain signal time series, we propose a functional mixed effects approach to model replicate-specific spectral densities as random curves varying about a deterministic population-mean spectrum. In…

Methodology · Statistics 2016-09-14 Joris Chau , Rainer von Sachs

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and behavioral patterns. Eye movement data offers a non-invasive diagnostic tool for ASD detection, as it is inherently…

Machine Learning · Computer Science 2026-01-12 Zhanpei Huang , Taochen chen , Fangqing Gu , Yiqun Zhang

Autism Spectrum Disorder (ASD) is a neuro-developmental syndrome resulting from alterations in the embryological brain before birth. This disorder distinguishes its patients by special socially restricted and repetitive behavior in addition…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hala Shamseddine , Safa Otoum , Azzam Mourad

Most brain disorders including Alzheimer's disease (AD) are related to alterations in the normal brain network organization and function. Exploring these network alterations using non-invasive and easy to use technique is a topic of great…

Neurons and Cognition · Quantitative Biology 2017-06-14 Aya Kabbara , Mahmoud Hassan , Mohamad Khalil , Wassim El Falou , Hassan Eid

Several methods have been developed to extract information from electroencephalograms (EEG). One of them is Phase-Amplitude Coupling (PAC) which is a type of Cross-Frequency Coupling (CFC) method, consisting in measure the synchronization…

Neurons and Cognition · Quantitative Biology 2021-04-13 Marco A. Formoso , Andrés Ortiz , Francisco J. Martínez-Murcia , Nicolás Gallego-Molina , Juan L. Luque

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

Self-initiated attention shifts play a critical role in voluntary behavior but are difficult to study due to the absence of explicit temporal markers. While previous studies have examined their neural correlates, it remains unclear how…

Signal Processing · Electrical Eng. & Systems 2026-05-19 Yuwen Zeng , Dengzhe Hou , Zhang Zhang , Sai Sun , Yongsong Huang , Chia-huei Tseng , Satoshi Shioiri

Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

In this paper we utilized the concept of stable phase synchronization topography - synchrostates - over the scalp derived from EEG recording for formulating brain connectivity network in Autism Spectrum Disorder (ASD) and typically-growing…

We present a didactic introduction to spectral Dynamic Causal Modelling (DCM), a Bayesian state-space modelling approach used to infer effective connectivity from non-invasive neuroimaging data. Spectral DCM is currently the most widely…

Neurons and Cognition · Quantitative Biology 2023-09-07 Leonardo Novelli , Karl Friston , Adeel Razi

Electroencephalograms (EEG) are noninvasive measurement signals of electrical neuronal activity in the brain. One of the current major statistical challenges is formally measuring functional dependency between those complex signals. This…

Methodology · Statistics 2021-05-14 Marco Antonio Pinto-Orellana , Peyman Mirtaheri , Hugo L. Hammer , Hernando Ombao

While graph convolution based methods have become the de-facto standard for graph representation learning, their applications to disease prediction tasks remain quite limited, particularly in the classification of neurodevelopmental and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Ibrahim Salim , A. Ben Hamza

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Brain connectivity analysis is crucial for understanding brain structure and neurological function, shedding light on the mechanisms of mental illness. To study the association between individual brain connectivity networks and the clinical…

In contemporary neuroscience, a key area of interest is dynamic effective connectivity, which is crucial for understanding the dynamic interactions and causal relationships between different brain regions. Dynamic effective connectivity can…

Methodology · Statistics 2024-05-30 Wei Zhang , Ivor Cribben , sonia Petrone , Michele Guindani

Depression and post-traumatic stress disorder (PTSD) are psychiatric conditions commonly associated with experiencing a traumatic event. Estimating mental health status through non-invasive techniques such as activity-based algorithms can…

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